Stroma Vascular Fraction- GO Cellular Component Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Cellular Component)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Cellular Component)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.05E-05 2 30 1232 85 8650 8.78E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005764 lysosome 1 30 1232 85 8650 8.78E-07
GO:0000323 lytic vacuole 2 28 1232 80 8650 2.45E-06
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.73E-04 2 14 1232 32 8650 5.00E-05
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0016283 eukaryotic 48S initiation complex 4 9 1232 13 8650 9.76E-06
GO:0005830 cytosolic ribosome (sensu Eukarya) 8 14 1232 32 8650 5.00E-05
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.73E-04 3 13 1232 29 8650 6.83E-05
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005843 cytosolic small ribosomal subunit (sensu Eukarya) 3 9 1232 13 8650 9.76E-06
GO:0016282 eukaryotic 43S preinitiation complex 6 12 1232 24 8650 3.39E-05
GO:0015935 small ribosomal subunit 7 10 1232 18 8650 4.87E-05
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
7.39E-04 4 151 1232 817 8650 2.46E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005578 extracellular matrix 5 53 1232 216 8650 3.31E-05
GO:0005615 extracellular space 11 61 1232 284 8650 5.02E-04
GO:0005576 extracellular 12 137 1232 749 8650 7.61E-04
GO:0001527 microfibril 14 3 1232 3 8650 2.88E-03
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.16E-02 2 4 1232 6 8650 4.83E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005637 nuclear inner membrane 16 4 1232 6 8650 4.83E-03
GO:0005639 integral to nuclear inner membrane 21 3 1232 4 8650 1.03E-02
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.28E-02 4 425 1232 2721 8650 7.45E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0008305 integrin complex 9 14 1232 32 8650 5.00E-05
GO:0005886 plasma membrane 10 202 1232 1137 8650 2.19E-04
GO:0005887 integral to plasma membrane 15 175 1232 1029 8650 4.56E-03
GO:0016021 integral to membrane 30 384 1232 2520 8650 4.86E-02
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.28E-02 3 32 1232 146 8650 7.46E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005885 Arp2/3 protein complex 13 4 1232 5 8650 1.82E-03
GO:0015629 actin cytoskeleton 17 32 1232 146 8650 7.46E-03
GO:0008290 F-actin capping protein complex 22 3 1232 4 8650 1.03E-02
 
 
 
Cluster 8 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.33E-02 2 95 1232 531 8650 9.12E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0000267 cell fraction 18 95 1232 531 8650 9.12E-03
GO:0005625 soluble fraction 29 33 1232 173 8650 4.60E-02
 
 
 
Cluster 9 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.33E-02 2 4 1232 7 8650 1.00E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0042101 T-cell receptor complex 20 4 1232 7 8650 1.00E-02
GO:0001772 immunological synapse 19 4 1232 7 8650 1.00E-02
 
 
 
Cluster 10 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.13E-02 2 4 1232 8 8650 1.78E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005583 fibrillar collagen 24 4 1232 8 8650 1.78E-02
GO:0005584 collagen type I 25 2 1232 2 8650 2.03E-02
 
 
 
Cluster 11 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.27E-02 3 10 1232 35 8650 2.08E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030173 integral to Golgi membrane 23 6 1232 15 8650 1.31E-02
GO:0042824 MHC class I peptide loading complex 26 2 1232 2 8650 2.03E-02
GO:0000139 Golgi membrane 28 9 1232 34 8650 4.40E-02
 
 
 
Cluster 12 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.86E-02 1 17 1232 74 8650 2.86E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005654 nucleoplasm 27 17 1232 74 8650 2.86E-02