|
UG Cluster |
LLID |
Symbol |
Name |
SVF Mean |
SVF q-val (%) |
ByP Mean |
ByP q-val (%) |
GO Biological Process Annotation |
||
| IMAGE:2013515 | Hs.296323 | 6446 | SGK | serum/glucocorticoid regulated kinase | -2.099 | 0.015 | -1.645 | 0.142 | protein modification; protein amino acid phosphorylation; sodium ion transport; apoptosis; response to stress; physiological process; programmed cell death; monovalent inorganic cation transport; phosphorylation; metal ion transport; | |
| IMAGE:325117 | Hs.412416 | 3091 | HIF1A | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.393 | 0.015 | -0.571 | 0.142 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; response to stress; cell communication; signal transduction; physiological process; regulation of transcription; | |
| IMAGE:412999 | Hs.272410 | 51311 | TLR8 | toll-like receptor 8 | -0.401 | 0.632 | -0.521 | 0.142 | inflammatory response; protein kinase cascade; NIK-I-kappaB/NF-kappaB cascade; detection of pest/pathogen/parasite; detection of viruses; response to wounding; response to pest/pathogen/parasite; response to virus; innate immune response; | |
| IMAGE:1894535 | Hs.77424 | 2209 | FCGR1A | Fc fragment of IgG, high affinity Ia, receptor for (CD64) | -0.227 | 0.083 | -0.292 | 0.142 | phagocytosis; phagocytosis\, engulfment; defense response; immune response; cell communication; signal transduction; | |
| IMAGE:108837 | Hs.303649 | 6347 | CCL2 | chemokine (C-C motif) ligand 2 | -1.474 | 0.015 | -2.279 | 0.180 | protein modification; protein amino acid phosphorylation; calcium ion homeostasis; metal ion homeostasis; anti-apoptosis; chemotaxis; inflammatory response; immune response; humoral immune response; cell communication; cell adhesion; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to cyclic nucleotide second messenger; protein kinase cascade; JAK-STAT cascade; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; response to bacteria; response to pathogenic bacteria; morphogenesis; organogenesis; phosphorylation; viral infectious cycle; viral genome replication; cyclic-nucleotide-mediated signaling; di-\, tri-valent inorganic cation homeostasis; response to chemical substance; taxis; negative regulation of apoptosis; innate immune response; | |
| IMAGE:323238 | Hs.789 | 2919 | CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -1.656 | 0.015 | -1.751 | 0.180 | chemotaxis; defense response; inflammatory response; immune response; signal transduction; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; intracellular signaling cascade; neurogenesis; pan-neural process; cell growth and/or maintenance; cell proliferation; negative regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; actin filament-based process; actin cytoskeleton organization and biogenesis; regulation of cell proliferation; response to chemical substance; taxis; innate immune response; | |
| IMAGE:324437 | Hs.789 | 2919 | CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -1.785 | 0.015 | -1.566 | 0.208 | chemotaxis; defense response; inflammatory response; immune response; signal transduction; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; intracellular signaling cascade; neurogenesis; pan-neural process; cell growth and/or maintenance; cell proliferation; negative regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; actin filament-based process; actin cytoskeleton organization and biogenesis; regulation of cell proliferation; response to chemical substance; taxis; innate immune response; | |
| IMAGE:72003 | Hs.193400 | 3570 | IL6R | interleukin 6 receptor | -0.729 | 0.034 | -0.840 | 0.208 | skeletal development; defense response; immune response; signal transduction; cell surface receptor linked signal transduction; development; biological_process; cell growth and/or maintenance; cell proliferation; organogenesis; | |
| IMAGE:1552481 | Hs.2488 | 3937 | LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -0.841 | 0.015 | -0.392 | 0.208 | defense response; immune response; signal transduction; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; intracellular signaling cascade; | |
| IMAGE:310406 | Hs.512234 | 3569 | IL6 | interleukin 6 (interferon, beta 2) | -0.625 | 0.026 | -0.763 | 0.238 | skeletal development; acute-phase response; immune response; humoral immune response; cell communication; signal transduction; cell surface receptor linked signal transduction; cell-cell signaling; development; biological_process; cell growth and/or maintenance; cell proliferation; positive regulation of cell proliferation; negative regulation of cell proliferation; response to pest/pathogen/parasite; organogenesis; regulation of cell proliferation; | |
| IMAGE:147050 | Hs.196384 | 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -1.167 | 0.015 | -0.586 | 0.238 | prostaglandin biosynthesis; cell motility; inflammatory response; physiological process; biological_process; cellular process; arachidonic acid metabolism; cyclooxygenase pathway; regulation of innate immune response; regulation of inflammatory response; | |
| IMAGE:1593311 | Hs.12013 | 6059 | ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | -0.203 | 0.374 | -0.343 | 0.238 | electron transport; transport; cell growth and/or maintenance; metabolism; viral assembly; viral capsid assembly; | |
| IMAGE:704407 | Hs.438040 | 931 | MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.357 | 0.503 | -0.438 | 0.312 | defense response; immune response; B-cell activation; lymphocyte activation; | |
| IMAGE:2315207 | Hs.164021 | 6372 | CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | -0.509 | 0.034 | -0.420 | 0.361 | chemotaxis; defense response; inflammatory response; immune response; cell communication; signal transduction; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; response to chemical substance; taxis; innate immune response; | |
| IMAGE:78148 | Hs.384944 | 6648 | SOD2 | superoxide dismutase 2, mitochondrial | -0.589 | 0.026 | -0.920 | 0.426 | oxygen and reactive oxygen species metabolism; superoxide metabolism; response to stress; response to oxidative stress; response to biotic stimulus; | |
| IMAGE:1667001 | Hs.2233 | 1440 | CSF3 | colony stimulating factor 3 (granulocyte) | -0.688 | 0.015 | -2.407 | 0.446 | defense response; immune response; cellular defense response; cell communication; signal transduction; cell surface receptor linked signal transduction; cell-cell signaling; development; biological_process; positive regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; regulation of cell proliferation; | |
| IMAGE:897806 | Hs.412416 | 3091 | HIF1A | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.373 | 0.034 | -0.543 | 0.446 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; response to stress; cell communication; signal transduction; physiological process; regulation of transcription; | |
| IMAGE:346860 | Hs.384944 | 6648 | SOD2 | superoxide dismutase 2, mitochondrial | -0.857 | 0.015 | -0.848 | 0.542 | oxygen and reactive oxygen species metabolism; superoxide metabolism; response to stress; response to oxidative stress; response to biotic stimulus; | |
| IMAGE:67759 | Hs.100194 | 241 | ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -1.243 | 0.015 | -0.843 | 0.542 | leukotriene metabolism; inflammatory response; response to wounding; response to pest/pathogen/parasite; leukotriene biosynthesis; innate immune response; icosanoid biosynthesis; | |
| IMAGE:840708 | Hs.384944 | 6648 | SOD2 | superoxide dismutase 2, mitochondrial | -0.710 | 0.015 | -0.824 | 0.619 | oxygen and reactive oxygen species metabolism; superoxide metabolism; response to stress; response to oxidative stress; response to biotic stimulus; | |
| IMAGE:1470886 | Hs.14155 | 23308 | ICOSL | inducible T-cell co-stimulator ligand | -0.580 | 0.632 | -0.600 | 0.619 | defense response; immune response; response to osmotic stress; hyperosmotic response; cell communication; signal transduction; positive regulation of T-cell proliferation; positive regulation of activated T-cell proliferation; T-cell activation; B-cell activation; regulation of activated T-cell proliferation; lymphocyte activation; | |
| IMAGE:950445 | Hs.91773 | 5515 | PPP2CA | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | -0.424 | 0.234 | -0.382 | 0.619 | regulation of cell cycle; MAPKKK cascade; inactivation of MAPK; regulation of cell growth; DNA dependent DNA replication; regulation of DNA replication; transcription; RNA processing; regulation of translation; protein modification; protein amino acid dephosphorylation; ceramide metabolism; induction of apoptosis; cell cycle; cell adhesion; intracellular signaling cascade; RNA splicing; response to organic substance; induction of programmed cell death; Wnt receptor signaling pathway; dephosphorylation; second-messenger-mediated signaling; regulation of Wnt receptor signaling pathway; cell differentiation; regulation of cell adhesion; negative regulation of cell growth; growth; regulation of growth; response to chemical substance; regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of tyrosine phosphorylation of STAT protein; translation; positive regulation of apoptosis; regulation of transcription; regulation of cell differentiation; sphingoid metabolism; | |
| IMAGE:2010404 | Hs.153837 | 4332 | MNDA | myeloid cell nuclear differentiation antigen | -0.323 | 0.053 | -0.222 | 0.619 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; immune response; cellular defense response; response to wounding; response to pest/pathogen/parasite; regulation of transcription; | |
| IMAGE:788088 | Hs.445864 | 5599 | MAPK8 | mitogen-activated protein kinase 8 | -0.314 | 2.344 | -0.427 | 0.632 | protein modification; protein amino acid phosphorylation; cell motility; response to stress; cell communication; signal transduction; protein kinase cascade; JNK cascade; physiological process; cellular process; phosphorylation; | |
| IMAGE:141115 | Hs.285401 | 1439 | CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.184 | 0.632 | -0.293 | 0.664 | cell communication; signal transduction; physiological process; respiratory gaseous exchange; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:85195 | Hs.9701 | 10912 | GADD45G | growth arrest and DNA-damage-inducible, gamma | -0.865 | 0.015 | -0.705 | 0.741 | MAPKKK cascade; activation of MAPKKK; DNA metabolism; DNA repair; protein biosynthesis; apoptosis; response to stress; response to DNA damage stimulus; development; physiological process; macromolecule biosynthesis; cellular process; programmed cell death; protein metabolism; cell differentiation; | |
| IMAGE:79629 | Hs.421986 | 7852 | CXCR4 | chemokine (C-X-C motif) receptor 4 | -1.128 | 0.015 | -0.419 | 0.741 | MAPKKK cascade; activation of MAPK; apoptosis; chemotaxis; defense response; inflammatory response; immune response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; neurogenesis; response to wounding; response to pest/pathogen/parasite; response to virus; organogenesis; programmed cell death; response to chemical substance; taxis; innate immune response; | |
| IMAGE:2421798 | Hs.179657 | 5329 | PLAUR | plasminogen activator, urokinase receptor | -1.784 | 0.015 | -1.150 | 0.871 | chemotaxis; signal transduction; cell surface receptor linked signal transduction; blood coagulation; hemostasis; response to chemical substance; taxis; coagulation; | |
| IMAGE:1607039 | Hs.150580 | 10209 | SUI1 | putative translation initiation factor | -0.917 | 0.015 | -0.596 | 1.252 | protein biosynthesis; translational initiation; regulation of protein biosynthesis; regulation of translation; regulation of translational initiation; response to stress; physiological process; cell growth and/or maintenance; regulation of biosynthesis; cellular process; translation; | |
| IMAGE:491770 | Hs.97199 | 22918 | C1QR1 | complement component 1, q subcomponent, receptor 1 | -0.632 | 0.121 | -0.645 | 1.356 | inflammatory response; heterophilic cell adhesion; cell-cell adhesion; macrophage activation; immune cell activation; | |
| IMAGE:840776 | Hs.296323 | 6446 | SGK | serum/glucocorticoid regulated kinase | -0.772 | 0.121 | -0.561 | 1.356 | protein modification; protein amino acid phosphorylation; sodium ion transport; apoptosis; response to stress; physiological process; programmed cell death; monovalent inorganic cation transport; phosphorylation; metal ion transport; | |
| IMAGE:487513 | Hs.410037 | 1490 | CTGF | connective tissue growth factor | -0.837 | 0.015 | -0.515 | 1.356 | regulation of cell growth; nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; DNA metabolism; cell motility; response to stress; cell communication; cell adhesion; ectoderm development; physiological process; cell growth and/or maintenance; epidermal differentiation; response to external stimulus; response to wounding; cellular process; cell growth; regulation of cellular process; | |
| IMAGE:814841 | Hs.126384 | 9103 | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | -0.423 | 0.881 | -0.297 | 1.356 | defense response; immune response; | |
| IMAGE:814841 | Hs.126384 | 2213 | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | -0.423 | 0.881 | -0.297 | 1.356 | defense response; immune response; cell communication; signal transduction; physiological process; cell growth and/or maintenance; cellular process; | |
| IMAGE:841340 | Hs.352018 | 6890 | TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.875 | 0.015 | -0.474 | 1.465 | oligopeptide transport; defense response; immune response; peptide transport; | |
| IMAGE:725407 | Hs.436249 | 57154 | SMURF1 | E3 ubiquitin ligase SMURF1 | -0.401 | 0.015 | -0.446 | 1.465 | protein modification; ubiquitin-dependent protein catabolism; ubiquitin cycle; development; ectoderm development; histogenesis; cellular process; protein ubiquitination; cell differentiation; regulation of BMP signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of BMP signaling pathway; protein ubiquitination during ubiquitin-dependent protein catabolism; | |
| IMAGE:1874367 | Hs.75498 | 6364 | CCL20 | chemokine (C-C motif) ligand 20 | -1.230 | 0.015 | -0.503 | 1.591 | chemotaxis; defense response; inflammatory response; immune response; cell communication; signal transduction; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); response to chemical substance; taxis; innate immune response; | |
| IMAGE:256907 | Hs.102484 | 2940 | GSTA3 | glutathione S-transferase A3 | -0.234 | 0.881 | -0.500 | 1.591 | response to stress; physiological process; metabolism; | |
| IMAGE:80344 | Hs.362807 | 3575 | IL7R | interleukin 7 receptor | -0.832 | 0.026 | -0.360 | 1.591 | regulation of DNA recombination; DNA recombination; defense response; immune response; signal transduction; cell surface receptor linked signal transduction; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:251591 | Hs.283565 | 8061 | FOSL1 | FOS-like antigen 1 | -0.398 | 0.015 | -0.946 | 1.823 | regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; chemotaxis; immune response; cellular defense response; positive regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; response to virus; regulation of cell proliferation; response to chemical substance; taxis; | |
| IMAGE:1046484 | Hs.104624 | 366 | AQP9 | aquaporin 9 | -0.553 | 0.015 | -0.519 | 1.823 | transport; water transport; defense response; immune response; cell growth and/or maintenance; fluid transport; | |
| IMAGE:2345206 | Hs.1652 | 1236 | CCR7 | chemokine (C-C motif) receptor 7 | -0.725 | 1.412 | -0.396 | 2.070 | chemotaxis; inflammatory response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; response to wounding; response to pest/pathogen/parasite; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); response to chemical substance; taxis; innate immune response; | |
| IMAGE:898092 | Hs.410037 | 1490 | CTGF | connective tissue growth factor | -1.407 | 0.015 | -0.952 | 2.626 | regulation of cell growth; nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; DNA metabolism; cell motility; response to stress; cell communication; cell adhesion; ectoderm development; physiological process; cell growth and/or maintenance; epidermal differentiation; response to external stimulus; response to wounding; cellular process; cell growth; regulation of cellular process; | |
| IMAGE:1592021 | Hs.278568 | 3075 | HF1 | H factor 1 (complement) | -1.313 | 0.015 | -0.568 | 2.626 | complement activation; complement activation\, alternative pathway; | |
| IMAGE:511647 | Hs.17377 | 23603 | CORO1C | coronin, actin binding protein, 1C | -0.179 | 0.190 | -0.360 | 2.626 | endocytosis; phagocytosis; cell communication; signal transduction; | |
| IMAGE:488145 | Hs.445466 | 2359 | FPRL2 | formyl peptide receptor-like 2 | -0.831 | 0.015 | -0.299 | 3.091 | cell motility; chemotaxis; cell communication; signal transduction; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; cellular process; response to chemical substance; taxis; | |
| IMAGE:526657 | Hs.15535 | 6924 | TCEB3 | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | -1.320 | 0.015 | -1.006 | 4.221 | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; transcription; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; defense response; response to biotic stimulus; | |
| IMAGE:1572582 | Hs.196352 | 4689 | NCF4 | neutrophil cytosolic factor 4, 40kDa | -0.751 | 0.234 | -0.344 | 4.221 | electron transport; defense response; signal transduction; intracellular signaling cascade; metabolism; response to biotic stimulus; | |
| IMAGE:135247 | Hs.177574 | 5612 | PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) | -0.279 | 0.881 | -0.141 | 5.090 | regulation of translation; response to stress; cell communication; signal transduction; physiological process; negative regulation of cell proliferation; regulation of cell proliferation; translation; | |
| IMAGE:840783 | Hs.380627 | 54918 | CKLFSF6 | chemokine-like factor super family 6 | -1.214 | 0.015 | -0.425 | 6.151 | chemotaxis; response to chemical substance; taxis; | |
| IMAGE:868380 | Hs.352642 | 2212 | FCGR2A | Fc fragment of IgG, low affinity IIa, receptor for (CD32) | -0.811 | 0.015 | -0.254 | 6.151 | defense response; immune response; | |
| IMAGE:740117 | Hs.166120 | 3665 | IRF7 | interferon regulatory factor 7 | -0.654 | 0.015 | -0.406 | 7.605 | negative regulation of transcription from Pol II promoter; transcription\, DNA-dependent; transcription initiation; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; transcription initiation from Pol II promoter; response to stress; inflammatory response; response to DNA damage stimulus; response to wounding; response to pest/pathogen/parasite; response to virus; response to endogenous stimulus; innate immune response; regulation of transcription; negative regulation of transcription\, DNA-dependent; viral induction of host immune response; passive viral induction of host immune response; | |
| IMAGE:593690 | Hs.270737 | 10673 | TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.437 | 0.034 | -0.272 | 7.605 | defense response; immune response; cell communication; signal transduction; cell growth and/or maintenance; cell proliferation; positive regulation of cell proliferation; regulation of cell proliferation; | |
| IMAGE:360436 | Hs.285313 | 1316 | COPEB | core promoter element binding protein | -0.391 | 0.015 | -0.532 | 9.421 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; cell growth and/or maintenance; cell growth; lymphocyte differentiation; B-cell differentiation; B-cell activation; regulation of transcription; | |
| IMAGE:841226 | Hs.197298 | 10625 | IVNS1ABP | influenza virus NS1A binding protein | -0.552 | 0.015 | -0.293 | 9.421 | transcription\, DNA-dependent; transcription from Pol III promoter; RNA processing; RNA splicing; response to pest/pathogen/parasite; response to virus; | |
| IMAGE:704020 | Hs.285401 | 1439 | CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.415 | 0.632 | -0.221 | 9.421 | cell communication; signal transduction; physiological process; respiratory gaseous exchange; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:71101 | Hs.82353 | 10544 | PROCR | protein C receptor, endothelial (EPCR) | -0.458 | 0.015 | -0.202 | 9.421 | inflammatory response; blood coagulation; hemostasis; response to wounding; response to pest/pathogen/parasite; innate immune response; coagulation; | |
| IMAGE:146671 | Hs.82112 | 3554 | IL1R1 | interleukin 1 receptor, type I | -0.514 | 1.412 | -0.396 | 16.164 | defense response; inflammatory response; immune response; signal transduction; cell surface receptor linked signal transduction; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:417300 | Hs.296941 | 3078 | HFL1 | H factor (complement)-like 1 | -1.096 | 0.015 | -0.395 | 16.164 | complement activation; humoral defense mechanism (sensu Vertebrata); | |
| IMAGE:753931 | Hs.421986 | 7852 | CXCR4 | chemokine (C-X-C motif) receptor 4 | -1.389 | 0.015 | -0.350 | 16.164 | MAPKKK cascade; activation of MAPK; apoptosis; chemotaxis; defense response; inflammatory response; immune response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; neurogenesis; response to wounding; response to pest/pathogen/parasite; response to virus; organogenesis; programmed cell death; response to chemical substance; taxis; innate immune response; | |
| IMAGE:489729 | Hs.18063 | 2113 | ETS1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | -1.058 | 0.015 | -0.292 | 16.164 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; transcription from Pol II promoter; defense response; immune response; physiological process; cell growth and/or maintenance; negative regulation of cell proliferation; cellular process; regulation of cell proliferation; regulation of transcription; | |
| IMAGE:2568090 | Hs.458288 | 51495 | HSPC121 | butyrate-induced transcript 1 | -0.305 | 2.344 | -0.253 | 16.164 | intracellular signaling cascade; protein kinase cascade; NIK-I-kappaB/NF-kappaB cascade; JNK cascade; activation of JUNK; small GTPase mediated signal transduction; RAC protein signal transduction; | |
| IMAGE:148968 | Hs.370849 | 4092 | MADH7 | MAD, mothers against decapentaplegic homolog 7 (Drosophila) | -0.257 | 0.632 | -0.183 | 16.164 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; response to stress; transmembrane receptor protein serine/threonine kinase signaling pathway; transforming growth factor beta receptor signaling pathway; physiological process; regulation of transcription; | |
| IMAGE:1525461 | Hs.103755 | 8767 | RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.931 | 0.015 | -0.170 | 16.164 | protein modification; protein amino acid phosphorylation; apoptosis; inflammatory response; cell communication; signal transduction; response to wounding; response to pest/pathogen/parasite; phosphorylation; regulation of apoptosis; innate immune response; | |
| IMAGE:1517162 | Hs.387787 | 8302 | KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.280 | 1.412 | -0.167 | 16.164 | cell communication; heterophilic cell adhesion; signal transduction; humoral defense mechanism (sensu Vertebrata); cell-cell adhesion; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:1090339 | Hs.2605 | 10871 | CMRF35 | CMRF35 leukocyte immunoglobulin-like receptor | -0.319 | 2.344 | -0.144 | 16.164 | immune response; cellular defense response; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:1911099 | Hs.271387 | 6355 | CCL8 | chemokine (C-C motif) ligand 8 | -0.510 | 0.015 | -0.143 | 16.164 | calcium ion transport; exocytosis; chemotaxis; defense response; inflammatory response; immune response; cell communication; signal transduction; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; response to virus; di-\, tri-valent inorganic cation transport; siderochrome transport; vesicle-mediated transport; metal ion transport; response to chemical substance; taxis; secretory pathway; innate immune response; | |
| IMAGE:665674 | Hs.250882 | 624 | BDKRB2 | bradykinin receptor B2 | -0.439 | 0.079 | -0.137 | 16.164 | muscle contraction; smooth muscle contraction; inflammatory response; cell surface receptor linked signal transduction; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; physiological process; sensory perception; circulation; detection of external stimulus; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:1606261 | Hs.46348 | 623 | BDKRB1 | bradykinin receptor B1 | -0.362 | 0.154 | -0.124 | 16.164 | inflammatory response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:276714 | Hs.356838 | 9441 | CRSP7 | cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa | -0.234 | 0.034 | -0.109 | 16.164 | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; transcription; transcription initiation; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; transcription initiation from Pol II promoter; defense response; response to biotic stimulus; | |
| IMAGE:784179 | Hs.2563 | 6863 | TAC1 | tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) | -0.117 | 1.412 | -0.092 | 16.164 | cell communication; G-protein coupled receptor protein signaling pathway; tachykinin signaling pathway; neuropeptide signaling pathway; cell-cell signaling; synaptic transmission; development; insemination; detection of external stimulus; detection of abiotic stimulus; response to abiotic stimulus; transmission of nerve impulse; | |
| IMAGE:79782 | Hs.414455 | 7716 | ZNF161 | zinc finger protein 161 | -0.135 | 2.344 | -0.085 | 16.164 | regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; immune response; cellular defense response; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:460398 | Hs.73817 | 6348 | CCL3 | chemokine (C-C motif) ligand 3 | -2.263 | 0.015 | -0.435 | 24.193 | calcium ion homeostasis; metal ion homeostasis; exocytosis; cell motility; chemotaxis; defense response; inflammatory response; immune response; organelle organization and biogenesis; cytoskeleton organization and biogenesis; cell communication; signal transduction; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; cellular process; siderochrome transport; humoral defense mechanism (sensu Vertebrata); vesicle-mediated transport; viral genome replication; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); di-\, tri-valent inorganic cation homeostasis; response to chemical substance; taxis; secretory pathway; regulation of viral genome replication; innate immune response; regulation of viral life cycle; | |
| IMAGE:1536968 | Hs.3003 | 916 | CD3E | CD3E antigen, epsilon polypeptide (TiT3 complex) | -0.358 | 0.015 | -0.202 | 24.193 | protein complex assembly; apoptosis; cell surface receptor linked signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; signal complex formation; G-protein coupled receptor protein signaling pathway; protein metabolism; positive regulation of T-cell proliferation; T-cell activation; regulation of T-cell proliferation; regulation of apoptosis; lymphocyte activation; positive regulation of lymphocyte proliferation; | |
| IMAGE:133136 | Hs.110713 | 7913 | DEK | DEK oncogene (DNA binding) | -0.618 | 2.344 | -0.183 | 24.193 | regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; cotranslational membrane targeting; SRP-dependent cotranslational membrane targeting; cell communication; signal transduction; physiological process; cell growth and/or maintenance; cellular process; viral infectious cycle; viral genome replication; | |
| IMAGE:687875 | Hs.181301 | 1520 | CTSS | cathepsin S | -0.910 | 0.015 | -0.106 | 24.193 | proteolysis and peptidolysis; defense response; immune response; protein catabolism; | |
| IMAGE:753236 | Hs.502 | 6891 | TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | -0.356 | 0.015 | -0.090 | 24.193 | protein complex assembly; transport; intracellular protein transport; protein transport; peptide transport; protein metabolism; antigen presentation\, endogenous antigen; antigen processing\, endogenous antigen via MHC class I; antigen processing; intracellular transport; cytosol to ER transport; antigen presentation\, peptide antigen; antigen presentation\, endogenous peptide antigen; | |
| IMAGE:213502 | Hs.443057 | 963 | CD53 | CD53 antigen | -1.759 | 0.015 | -0.138 | 27.866 | cell communication; signal transduction; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:840753 | Hs.489044 | 6352 | CCL5 | chemokine (C-C motif) ligand 5 | -0.427 | 0.053 | -0.108 | 27.866 | oxygen and reactive oxygen species metabolism; calcium ion homeostasis; metal ion homeostasis; exocytosis; cell motility; chemotaxis; response to stress; inflammatory response; immune response; cellular defense response; response to oxidative stress; cell communication; cell adhesion; signal transduction; cell-cell signaling; response to biotic stimulus; response to wounding; response to pest/pathogen/parasite; response to virus; cellular process; siderochrome transport; vesicle-mediated transport; di-\, tri-valent inorganic cation homeostasis; response to chemical substance; taxis; secretory pathway; innate immune response; | |
| IMAGE:306013 | Hs.438040 | 931 | MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.309 | 1.412 | -0.102 | 27.866 | defense response; immune response; B-cell activation; lymphocyte activation; | |
| IMAGE:714453 | Hs.75545 | 3566 | IL4R | interleukin 4 receptor | -1.120 | 0.015 | -0.070 | 30.534 | defense response; immune response; cell communication; signal transduction; | |
| IMAGE:290230 | Hs.14453 | 3394 | ICSBP1 | interferon consensus sequence binding protein 1 | -0.630 | 0.034 | -0.136 | 32.645 | negative regulation of transcription from Pol II promoter; transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; defense response; immune response; regulation of transcription; negative regulation of transcription\, DNA-dependent; | |
| IMAGE:80948 | Hs.381568 | 3512 | IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | -0.488 | 0.026 | -0.127 | 32.645 | defense response; immune response; | |
| IMAGE:290724 | Hs.90598 | 4276 | MICA | MHC class I polypeptide-related sequence A | -0.777 | 0.015 | -0.101 | 32.645 | response to stress; defense response; immune response; cellular defense response; cell adhesion; physiological process; cell recognition; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:1637203 | Hs.9641 | 712 | C1QA | complement component 1, q subcomponent, alpha polypeptide | -1.066 | 0.234 | -0.095 | 32.645 | complement activation; complement activation\, classical pathway; cell communication; cell-cell signaling; | |
| IMAGE:1592837 | Hs.174195 | 10581 | IFITM2 | interferon induced transmembrane protein 2 (1-8D) | -0.706 | 0.015 | -0.136 | 34.583 | defense response; immune response; | |
| IMAGE:714213 | Hs.82359 | 355 | TNFRSF6 | tumor necrosis factor receptor superfamily, member 6 | -0.586 | 0.026 | -0.120 | 36.060 | protein complex assembly; apoptosis; anti-apoptosis; induction of apoptosis; defense response; immune response; cell communication; signal transduction; induction of programmed cell death; protein metabolism; regulation of apoptosis; positive regulation of apoptosis; negative regulation of apoptosis; | |
| IMAGE:784337 | Hs.436042 | 6387 | CXCL12 | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | -0.632 | 0.083 | -0.081 | 36.060 | calcium ion homeostasis; metal ion homeostasis; chemotaxis; defense response; inflammatory response; immune response; cell communication; cell adhesion; signal transduction; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; cell-cell signaling; physiological process; circulation; regulation of actin polymerization and/or depolymerization; actin polymerization and/or depolymerization; response to wounding; response to pest/pathogen/parasite; response to virus; di-\, tri-valent inorganic cation homeostasis; regulation of actin filament length; response to chemical substance; taxis; innate immune response; | |
| IMAGE:2314294 | Hs.897 | 2205 | FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -1.315 | 0.015 | -0.067 | 36.060 | defense response; immune response; | |
| IMAGE:502814 | Hs.421194 | 8460 | TPST1 | tyrosylprotein sulfotransferase 1 | -1.713 | 0.015 | -0.196 | 37.383 | protein amino acid sulfation; peptidyl-tyrosine sulfation; inflammatory response; response to wounding; response to pest/pathogen/parasite; peptidyl-tyrosine modification; innate immune response; | |
| IMAGE:1968136 | Hs.118651 | 3087 | HHEX | hematopoietically expressed homeobox | -0.613 | 0.034 | -0.124 | 37.383 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; development; biological_process; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); regulation of transcription; | |
| IMAGE:30470 | Hs.306230 | 10990 | LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | -0.357 | 0.632 | -0.074 | 37.383 | defense response; immune response; signal transduction; cell surface receptor linked signal transduction; | |
| IMAGE:30470 | Hs.306230 | 10288 | LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | -0.357 | 0.632 | -0.074 | 37.383 | defense response; immune response; | |
| IMAGE:897906 | Hs.2554 | 6480 | SIAT1 | sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase) | -0.463 | 0.298 | -0.071 | 38.650 | carbohydrate metabolism; protein modification; protein amino acid glycosylation; immune response; humoral immune response; development; glycoprotein biosynthesis; oligosaccharide metabolism; response to pest/pathogen/parasite; growth; | |
| IMAGE:950689 | Hs.446375 | 10982 | MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | -0.787 | 0.015 | -0.067 | 38.650 | immune response; cellular defense response; cell communication; signal transduction; cell growth and/or maintenance; cell proliferation; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:2566158 | Hs.182018 | 3654 | IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.167 | 2.344 | 0.877 | 0.142 | protein modification; protein amino acid phosphorylation; defense response; cell communication; signal transduction; enzyme linked receptor protein signaling pathway; transmembrane receptor protein serine/threonine kinase signaling pathway; NIK-I-kappaB/NF-kappaB cascade; activation of NF-kappaB-inducing kinase; response to biotic stimulus; phosphorylation; regulation of transcription; positive regulation of transcription; autophosphorylation; | |
| IMAGE:145932 | Hs.433300 | 2207 | FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -2.197 | 0.015 | 1.392 | 0.180 | defense response; immune response; signal transduction; cell surface receptor linked signal transduction; | |
| IMAGE:133518 | Hs.446375 | 10982 | MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | -0.919 | 0.015 | 0.914 | 0.361 | immune response; cellular defense response; cell communication; signal transduction; cell growth and/or maintenance; cell proliferation; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:343867 | Hs.76364 | 199 | AIF1 | allograft inflammatory factor 1 | -1.460 | 0.015 | 0.853 | 0.446 | regulation of cell cycle; response to stress; inflammatory response; cell cycle arrest; physiological process; negative regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; regulation of cell proliferation; innate immune response; | |
| IMAGE:244764 | Hs.77873 | 80381 | B7H3 | B7 homolog 3 | -0.994 | 0.015 | 1.076 | 0.446 | defense response; immune response; cell growth and/or maintenance; cell proliferation; | |
| IMAGE:82903 | Hs.370937 | 6892 | TAPBP | TAP binding protein (tapasin) | -0.376 | 0.026 | 1.117 | 0.475 | protein complex assembly; retrograde transport\, Golgi to ER; defense response; immune response; protein metabolism; antigen processing\, endogenous antigen via MHC class I; antigen processing; secretory pathway; Golgi vesicle transport; peptide stabilization; peptide antigen stabilization; | |
| IMAGE:431805 | Hs.2554 | 6480 | SIAT1 | sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase) | -0.682 | 0.015 | 1.463 | 0.475 | carbohydrate metabolism; protein modification; protein amino acid glycosylation; immune response; humoral immune response; development; glycoprotein biosynthesis; oligosaccharide metabolism; response to pest/pathogen/parasite; growth; | |
| IMAGE:855745 | Hs.103995 | 3503 | FLJ27099 | FLJ27099 protein | -1.997 | 0.015 | 1.387 | 0.513 | defense response; immune response; | |
| IMAGE:1325655 | Hs.489044 | 6352 | CCL5 | chemokine (C-C motif) ligand 5 | -0.287 | 0.298 | 0.462 | 0.542 | oxygen and reactive oxygen species metabolism; calcium ion homeostasis; metal ion homeostasis; exocytosis; cell motility; chemotaxis; response to stress; inflammatory response; immune response; cellular defense response; response to oxidative stress; cell communication; cell adhesion; signal transduction; cell-cell signaling; response to biotic stimulus; response to wounding; response to pest/pathogen/parasite; response to virus; cellular process; siderochrome transport; vesicle-mediated transport; di-\, tri-valent inorganic cation homeostasis; response to chemical substance; taxis; secretory pathway; innate immune response; | |
| IMAGE:713974 | Hs.174142 | 1436 | CSF1R | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | -1.796 | 0.015 | 1.469 | 0.619 | protein modification; protein amino acid phosphorylation; cell communication; signal transduction; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; development; biological_process; cell growth and/or maintenance; cell proliferation; humoral defense mechanism (sensu Vertebrata); phosphorylation; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:183337 | Hs.351279 | 3108 | HLA-DMA | major histocompatibility complex, class II, DM alpha | -1.297 | 0.015 | 0.872 | 0.741 | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:246703 | Hs.6483 | 8481 | OFD1 | oral-facial-digital syndrome 1 | -0.209 | 0.053 | 0.749 | 0.917 | defense response; response to biotic stimulus; | |
| IMAGE:110788 | Hs.56729 | 4046 | LSP1 | lymphocyte-specific protein 1 | -1.612 | 0.015 | 1.000 | 0.917 | cell motility; immune response; cellular defense response; cell communication; signal transduction; response to wounding; response to pest/pathogen/parasite; cellular process; | |
| IMAGE:841332 | Hs.292738 | 397 | ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.796 | 0.015 | 0.510 | 1.004 | defense response; immune response; negative regulation of cell adhesion; small GTPase mediated signal transduction; Rho protein signal transduction; development; biological_process; actin filament-based process; actin cytoskeleton organization and biogenesis; regulation of cell adhesion; | |
| IMAGE:811161 | Hs.9573 | 23 | ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -0.594 | 0.015 | 0.827 | 1.004 | protein biosynthesis; transport; inflammatory response; cell growth and/or maintenance; macromolecule biosynthesis; response to wounding; response to pest/pathogen/parasite; protein metabolism; innate immune response; | |
| IMAGE:1632252 | Hs.9641 | 712 | C1QA | complement component 1, q subcomponent, alpha polypeptide | -1.544 | 0.015 | 0.902 | 1.004 | complement activation; complement activation\, classical pathway; cell communication; cell-cell signaling; | |
| IMAGE:1876531 | Hs.421724 | 1511 | CTSG | cathepsin G | -1.826 | 0.015 | 1.087 | 1.004 | proteolysis and peptidolysis; defense response; immune response; protein catabolism; | |
| IMAGE:323506 | Hs.324473 | 5594 | MAPK1 | mitogen-activated protein kinase 1 | -0.274 | 1.412 | 0.989 | 1.252 | protein modification; protein amino acid phosphorylation; induction of apoptosis; chemotaxis; response to stress; cell cycle; cell communication; signal transduction; synaptic transmission; physiological process; cell proliferation; induction of programmed cell death; phosphorylation; transmission of nerve impulse; response to chemical substance; taxis; positive regulation of apoptosis; | |
| IMAGE:1154773 | Hs.111903 | 2217 | FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -1.494 | 0.015 | 0.508 | 1.356 | defense response; immune response; pregnancy; physiological process; | |
| IMAGE:770681 | Hs.17483 | 920 | CD4 | CD4 antigen (p55) | -1.112 | 0.015 | 0.848 | 1.356 | defense response; immune response; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; lymphocyte differentiation; T-cell differentiation; positive regulation of cytokine biosynthesis; T-cell activation; T-cell selection; regulation of interleukin-2 biosynthesis; positive regulation of interleukin-2 biosynthesis; | |
| IMAGE:841059 | Hs.82422 | 822 | CAPG | capping protein (actin filament), gelsolin-like | -0.623 | 0.015 | 1.191 | 1.356 | protein complex assembly; response to stress; response to biotic stimulus; response to pest/pathogen/parasite; protein metabolism; | |
| IMAGE:2572285 | Hs.111903 | 2217 | FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -1.327 | 0.015 | 0.717 | 1.465 | defense response; immune response; pregnancy; physiological process; | |
| IMAGE:68894 | Hs.111903 | 2217 | FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -1.083 | 0.015 | 0.990 | 1.465 | defense response; immune response; pregnancy; physiological process; | |
| IMAGE:148469 | Hs.9963 | 7305 | TYROBP | TYRO protein tyrosine kinase binding protein | -2.312 | 0.015 | 1.050 | 1.465 | immune response; cellular defense response; signal transduction; intracellular signaling cascade; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:359395 | Hs.370431 | 8774 | NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.572 | 0.034 | 1.063 | 1.465 | protein complex assembly; intracellular protein transport; intra-Golgi transport; membrane fusion; cellular process; protein transport; protein metabolism; secretory pathway; intracellular transport; Golgi vesicle transport; protein stabilization; | |
| IMAGE:2315876 | Hs.405479 | 7176 | TPS1 | tryptase, alpha | -2.113 | 0.015 | 1.580 | 1.465 | proteolysis and peptidolysis; defense response; response to biotic stimulus; protein catabolism; | |
| IMAGE:196282 | Hs.174142 | 1436 | CSF1R | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | -0.931 | 0.015 | 0.703 | 1.591 | protein modification; protein amino acid phosphorylation; cell communication; signal transduction; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; development; biological_process; cell growth and/or maintenance; cell proliferation; humoral defense mechanism (sensu Vertebrata); phosphorylation; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:511043 | Hs.434081 | 5721 | PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | -0.514 | 0.015 | 0.498 | 2.070 | defense response; immune response; | |
| IMAGE:868332 | Hs.914 | 3113 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -1.937 | 0.015 | 1.178 | 2.346 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:244044 | Hs.94953 | 714 | C1QG | complement component 1, q subcomponent, gamma polypeptide | -1.159 | 0.015 | 1.403 | 2.346 | defense response; immune response; complement activation; complement activation\, classical pathway; | |
| IMAGE:786308 | Hs.17483 | 920 | CD4 | CD4 antigen (p55) | -0.440 | 0.015 | 0.584 | 2.626 | defense response; immune response; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; lymphocyte differentiation; T-cell differentiation; positive regulation of cytokine biosynthesis; T-cell activation; T-cell selection; regulation of interleukin-2 biosynthesis; positive regulation of interleukin-2 biosynthesis; | |
| IMAGE:1915096 | Hs.67846 | 11006 | LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 | -0.446 | 0.015 | 0.484 | 3.091 | defense response; immune response; | |
| IMAGE:856447 | Hs.14623 | 10437 | IFI30 | interferon, gamma-inducible protein 30 | -1.979 | 0.015 | 1.104 | 3.091 | defense response; immune response; | |
| IMAGE:1912458 | Hs.673 | 3592 | IL12A | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | -0.602 | 0.015 | 0.677 | 3.593 | defense response; immune response; | |
| IMAGE:342647 | Hs.234521 | 7867 | MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -0.409 | 0.015 | 0.724 | 3.593 | protein modification; protein amino acid phosphorylation; response to stress; cell communication; signal transduction; physiological process; phosphorylation; | |
| IMAGE:324935 | Hs.370937 | 6892 | TAPBP | TAP binding protein (tapasin) | -0.421 | 0.015 | 0.830 | 3.593 | protein complex assembly; retrograde transport\, Golgi to ER; defense response; immune response; protein metabolism; antigen processing\, endogenous antigen via MHC class I; antigen processing; secretory pathway; Golgi vesicle transport; peptide stabilization; peptide antigen stabilization; | |
| IMAGE:795343 | Hs.77424 | 2209 | FCGR1A | Fc fragment of IgG, high affinity Ia, receptor for (CD64) | -0.444 | 0.154 | 0.551 | 4.221 | phagocytosis; phagocytosis\, engulfment; defense response; immune response; cell communication; signal transduction; | |
| IMAGE:85497 | Hs.2253 | 717 | C2 | complement component 2 | -0.532 | 0.015 | 0.812 | 4.221 | proteolysis and peptidolysis; complement activation; complement activation\, classical pathway; protein catabolism; | |
| IMAGE:2333826 | Hs.184018 | 9450 | LY86 | lymphocyte antigen 86 | -0.469 | 0.015 | 0.448 | 5.090 | apoptosis; inflammatory response; immune response; humoral immune response; cell communication; signal transduction; cell growth and/or maintenance; cell proliferation; response to wounding; response to pest/pathogen/parasite; programmed cell death; innate immune response; | |
| IMAGE:343987 | Hs.44926 | 1803 | DPP4 | dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2) | -0.598 | 0.374 | 0.699 | 5.090 | proteolysis and peptidolysis; defense response; immune response; protein catabolism; | |
| IMAGE:2028984 | Hs.436042 | 6387 | CXCL12 | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | -0.416 | 0.015 | 0.769 | 5.090 | calcium ion homeostasis; metal ion homeostasis; chemotaxis; defense response; inflammatory response; immune response; cell communication; cell adhesion; signal transduction; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; cell-cell signaling; physiological process; circulation; regulation of actin polymerization and/or depolymerization; actin polymerization and/or depolymerization; response to wounding; response to pest/pathogen/parasite; response to virus; di-\, tri-valent inorganic cation homeostasis; regulation of actin filament length; response to chemical substance; taxis; innate immune response; | |
| IMAGE:1606829 | Hs.222874 | 9759 | HDAC4 | histone deacetylase 4 | -0.280 | 0.015 | 0.254 | 6.151 | establishment and/or maintenance of chromatin architecture; transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; inflammatory response; cell cycle; development; neurogenesis; biological_process; cell proliferation; response to wounding; response to pest/pathogen/parasite; organogenesis; regulation of myogenesis; chromatin modification; lymphocyte differentiation; B-cell differentiation; B-cell activation; innate immune response; regulation of transcription; negative regulation of myogenesis; | |
| IMAGE:969636 | Hs.76691 | 8303 | SNN | stannin | -0.529 | 0.015 | 0.369 | 6.151 | response to stress; physiological process; response to external stimulus; response to abiotic stimulus; | |
| IMAGE:320393 | Hs.387679 | 3117 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.980 | 0.015 | 0.562 | 6.151 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; regulation of transcription; | |
| IMAGE:2555187 | Hs.512633 | 5553 | PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.618 | 0.034 | 0.565 | 6.151 | xenobiotic metabolism; defense response; inflammatory response; immune response; heterophilic cell adhesion; metabolism; response to xenobiotic stimulus; response to wounding; response to pest/pathogen/parasite; cell-cell adhesion; innate immune response; | |
| IMAGE:417018 | Hs.163867 | 929 | CD14 | CD14 antigen | -1.369 | 0.015 | 0.715 | 6.151 | endocytosis; phagocytosis; apoptosis; defense response; inflammatory response; immune response; signal transduction; cell surface receptor linked signal transduction; response to wounding; response to pest/pathogen/parasite; programmed cell death; innate immune response; | |
| IMAGE:1584411 | Hs.241535 | 80833 | APOL3 | apolipoprotein L, 3 | -0.442 | 0.053 | 0.903 | 6.151 | transport; lipid transport; inflammatory response; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:50503 | Hs.375957 | 3689 | ITGB2 | integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) | -1.997 | 0.015 | 1.017 | 6.151 | cell adhesion; cell-matrix adhesion; cell surface receptor linked signal transduction; integrin-mediated signaling pathway; development; biological_process; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:1055217 | Hs.162754 | 3982 | LIM2 | lens intrinsic membrane protein 2, 19kDa | -0.415 | 0.026 | 0.281 | 7.605 | calcium ion transport; intercellular junction assembly; di-\, tri-valent inorganic cation transport; metal ion transport; intercellular junction assembly and/or maintenance; | |
| IMAGE:435858 | Hs.23262 | 6039 | RNASE6 | ribonuclease, RNase A family, k6 | -0.589 | 0.015 | 0.307 | 7.605 | RNA catabolism; defense response; macromolecule catabolism; response to biotic stimulus; RNA metabolism; | |
| IMAGE:417249 | Hs.118631 | 8914 | TIMELESS | timeless homolog (Drosophila) | -0.307 | 0.034 | 0.480 | 7.605 | rhythmic behavior; circadian rhythm; detection of external stimulus; detection of abiotic stimulus; response to abiotic stimulus; | |
| IMAGE:1851134 | Hs.241570 | 7124 | TNF | tumor necrosis factor (TNF superfamily, member 2) | -1.907 | 0.015 | 0.562 | 7.605 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; apoptosis; anti-apoptosis; defense response; inflammatory response; immune response; cell communication; heterophilic cell adhesion; leukocyte cell adhesion; signal transduction; cell-cell signaling; necrosis; pathogenesis; response to wounding; response to pest/pathogen/parasite; response to virus; programmed cell death; negative regulation of apoptosis; innate immune response; regulation of transcription; | |
| IMAGE:1470048 | Hs.77667 | 4061 | LY6E | lymphocyte antigen 6 complex, locus E | -0.568 | 0.015 | 0.689 | 7.605 | defense response; signal transduction; cell surface receptor linked signal transduction; response to biotic stimulus; | |
| IMAGE:376416 | Hs.376414 | 715 | C1R | complement component 1, r subcomponent | -1.354 | 0.015 | 0.808 | 7.605 | proteolysis and peptidolysis; defense response; immune response; complement activation; complement activation\, classical pathway; protein catabolism; | |
| IMAGE:1552744 | Hs.89476 | 914 | CD2 | CD2 antigen (p50), sheep red blood cell receptor | -1.253 | 0.015 | 0.934 | 7.605 | lipid raft polarization; induction of apoptosis; plasma membrane organization and biogenesis; cell adhesion; signal transduction; cell surface receptor linked signal transduction; induction of programmed cell death; cell-cell adhesion; natural killer cell activation; T-cell differentiation; regulation of dendritic cell activation; positive regulation of dendritic cell activation; T-cell activation; positive regulation of apoptosis; regulation of T-cell differentiation; regulation of lymphocyte differentiation; lymphocyte activation; | |
| IMAGE:430465 | Hs.50002 | 6363 | CCL19 | chemokine (C-C motif) ligand 19 | -0.404 | 0.015 | 0.956 | 7.605 | calcium ion homeostasis; metal ion homeostasis; chemotaxis; defense response; inflammatory response; immune response; cell communication; signal transduction; response to wounding; response to pest/pathogen/parasite; response to virus; di-\, tri-valent inorganic cation homeostasis; response to chemical substance; taxis; innate immune response; | |
| IMAGE:2510979 | Hs.180062 | 5696 | PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) | -0.849 | 0.015 | 1.030 | 7.605 | proteolysis and peptidolysis; ubiquitin-dependent protein catabolism; defense response; immune response; modification-dependent protein catabolism; protein catabolism; | |
| IMAGE:156097 | Hs.409934 | 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | -1.859 | 0.015 | 0.646 | 9.421 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:121275 | Hs.375115 | 3120 | HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | -1.600 | 0.015 | 0.732 | 9.421 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:756556 | Hs.384598 | 710 | SERPING1 | serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | -0.207 | 0.053 | 0.745 | 9.421 | complement activation; complement activation\, classical pathway; physiological process; blood coagulation; hemostasis; circulation; coagulation; | |
| IMAGE:247081 | Hs.200063 | 51564 | HDAC7A | histone deacetylase 7A | -0.557 | 0.015 | 0.792 | 9.421 | regulation of cell cycle; establishment and/or maintenance of chromatin architecture; transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; inflammatory response; cell cycle; neurogenesis; response to wounding; response to pest/pathogen/parasite; organogenesis; regulation of myogenesis; chromatin modification; lymphocyte differentiation; B-cell differentiation; B-cell activation; innate immune response; regulation of transcription; negative regulation of myogenesis; | |
| IMAGE:461769 | Hs.308026 | 3125 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.651 | 0.015 | 0.851 | 9.421 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:461769 | Hs.308026 | 3127 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.651 | 0.015 | 0.851 | 9.421 | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:461769 | Hs.308026 | 3126 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.651 | 0.015 | 0.851 | 9.421 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:186767 | Hs.308026 | 3125 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.692 | 0.015 | 1.114 | 9.421 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:186767 | Hs.308026 | 3126 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.692 | 0.015 | 1.114 | 9.421 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:186767 | Hs.308026 | 3127 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.692 | 0.015 | 1.114 | 9.421 | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:71434 | Hs.75348 | 5720 | PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.681 | 0.015 | 0.342 | 16.164 | defense response; immune response; | |
| IMAGE:236282 | Hs.2157 | 7454 | WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | -0.600 | 0.026 | 0.361 | 16.164 | protein complex assembly; defense response; ectoderm development; blood coagulation; hemostasis; actin polymerization and/or depolymerization; epidermal differentiation; response to biotic stimulus; protein metabolism; actin cytoskeleton organization and biogenesis; coagulation; | |
| IMAGE:486683 | Hs.278573 | 966 | CD59 | CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) | -0.432 | 0.015 | 0.471 | 16.164 | defense response; immune response; signal transduction; cell surface receptor linked signal transduction; blood coagulation; hemostasis; coagulation; | |
| IMAGE:2009477 | Hs.436949 | 923 | CD6 | CD6 antigen | -0.669 | 0.015 | 0.645 | 16.164 | defense response; immune response; cell communication; cell adhesion; | |
| IMAGE:198453 | Hs.381008 | 3133 | HLA-E | major histocompatibility complex, class I, E | -0.950 | 0.015 | 0.702 | 16.164 | defense response; immune response; antigen presentation; antigen presentation\, endogenous antigen; antigen processing\, endogenous antigen via MHC class I; antigen processing; | |
| IMAGE:810142 | Hs.274485 | 3107 | HLA-C | major histocompatibility complex, class I, C | -0.984 | 0.015 | 0.702 | 16.164 | defense response; immune response; antigen presentation; antigen presentation\, endogenous antigen; antigen processing\, endogenous antigen via MHC class I; antigen processing; | |
| IMAGE:417711 | Hs.308026 | 3126 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.517 | 0.015 | 0.714 | 16.164 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:417711 | Hs.308026 | 3125 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.517 | 0.015 | 0.714 | 16.164 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:417711 | Hs.308026 | 3127 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.517 | 0.015 | 0.714 | 16.164 | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:381066 | Hs.384598 | 710 | SERPING1 | serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | -0.313 | 1.412 | 0.763 | 16.164 | complement activation; complement activation\, classical pathway; physiological process; blood coagulation; hemostasis; circulation; coagulation; | |
| IMAGE:854444 | Hs.409934 | 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | -1.459 | 0.015 | 0.792 | 16.164 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:1476320 | Hs.949 | 4688 | NCF2 | neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2) | -1.587 | 0.015 | 0.806 | 16.164 | oxygen and reactive oxygen species metabolism; superoxide metabolism; immune response; cellular defense response; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:2448698 | Hs.308026 | 3127 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.801 | 0.015 | 0.903 | 16.164 | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:2448698 | Hs.308026 | 3125 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.801 | 0.015 | 0.903 | 16.164 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:2448698 | Hs.308026 | 3126 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.801 | 0.015 | 0.903 | 16.164 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:811024 | Hs.118110 | 684 | BST2 | bone marrow stromal cell antigen 2 | -0.451 | 0.881 | 0.908 | 16.164 | immune response; humoral immune response; cell communication; cell-cell signaling; development; biological_process; cell growth and/or maintenance; cell proliferation; response to pest/pathogen/parasite; | |
| IMAGE:83549 | Hs.376414 | 715 | C1R | complement component 1, r subcomponent | -0.949 | 0.015 | 1.006 | 16.164 | proteolysis and peptidolysis; defense response; immune response; complement activation; complement activation\, classical pathway; protein catabolism; | |
| IMAGE:183811 | Hs.387871 | 8743 | TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -3.139 | 0.015 | 1.200 | 16.164 | apoptosis; induction of apoptosis; defense response; immune response; cell communication; signal transduction; cell-cell signaling; programmed cell death; induction of programmed cell death; positive regulation of apoptosis; | |
| IMAGE:824340 | Hs.458275 | 4687 | NCF1 | neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1) | -2.715 | 0.015 | 1.214 | 16.164 | electron transport; oxygen and reactive oxygen species metabolism; superoxide metabolism; immune response; cellular defense response; signal transduction; intracellular signaling cascade; metabolism; response to wounding; response to pest/pathogen/parasite; | |
| IMAGE:281003 | Hs.407442 | 6965 | TRGV9 | T cell receptor gamma variable 9 | -0.251 | 2.344 | 0.260 | 24.193 | defense response; immune response; | |
| IMAGE:2012135 | Hs.155935 | 719 | C3AR1 | complement component 3a receptor 1 | -0.583 | 0.015 | 0.320 | 24.193 | cell motility; chemotaxis; muscle contraction; smooth muscle contraction; inflammatory response; immune response; cellular defense response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; physiological process; circulation; response to wounding; response to pest/pathogen/parasite; cellular process; response to chemical substance; taxis; innate immune response; | |
| IMAGE:2015083 | Hs.46465 | 10312 | TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a isoform 3 | -0.589 | 0.015 | 0.387 | 24.193 | hydrogen transport; immune response; cellular defense response; positive regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; monovalent inorganic cation transport; proton transport; regulation of cell proliferation; | |
| IMAGE:624360 | Hs.180062 | 5696 | PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) | -0.646 | 0.015 | 0.389 | 24.193 | proteolysis and peptidolysis; ubiquitin-dependent protein catabolism; defense response; immune response; modification-dependent protein catabolism; protein catabolism; | |
| IMAGE:2028332 | Hs.409934 | 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | -1.896 | 0.015 | 0.446 | 24.193 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:504226 | Hs.443057 | 963 | CD53 | CD53 antigen | -2.033 | 0.015 | 0.485 | 24.193 | cell communication; signal transduction; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:725649 | Hs.77810 | 4776 | NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | -0.590 | 0.015 | 0.524 | 24.193 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; transcription from Pol II promoter; inflammatory response; response to wounding; response to pest/pathogen/parasite; innate immune response; regulation of transcription; | |
| IMAGE:855258 | Hs.308026 | 3127 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.684 | 0.015 | 0.570 | 24.193 | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:855258 | Hs.308026 | 3126 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.684 | 0.015 | 0.570 | 24.193 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:855258 | Hs.308026 | 3125 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.684 | 0.015 | 0.570 | 24.193 | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:510383 | Hs.458414 | 8519 | IFITM1 | interferon induced transmembrane protein 1 (9-27) | -1.131 | 0.015 | 0.595 | 24.193 | regulation of cell cycle; defense response; immune response; cell cycle; signal transduction; cell surface receptor linked signal transduction; negative regulation of cell proliferation; regulation of cell proliferation; | |
| IMAGE:2541441 | Hs.384598 | 710 | SERPING1 | serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | -0.430 | 0.083 | 0.596 | 24.193 | complement activation; complement activation\, classical pathway; physiological process; blood coagulation; hemostasis; circulation; coagulation; | |
| IMAGE:487988 | Hs.415067 | 11151 | CORO1A | coronin, actin binding protein, 1A | -0.553 | 0.015 | 0.604 | 24.193 | M phase of mitotic cell cycle; nuclear division; transport; phagocytosis; phagosome formation; cell motility; mitosis; cell growth and/or maintenance; cellular process; | |
| IMAGE:153411 | Hs.409805 | 3122 | HLA-DRA | major histocompatibility complex, class II, DR alpha | -1.421 | 0.015 | 0.624 | 24.193 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:449043 | Hs.325978 | 10068 | IL18BP | interleukin 18 binding protein | -0.204 | 0.374 | 0.174 | 27.866 | defense response; immune response; | |
| IMAGE:47481 | Hs.85201 | 9976 | CLECSF2 | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced) | -0.449 | 2.344 | 0.247 | 27.866 | heterophilic cell adhesion; humoral defense mechanism (sensu Vertebrata); cell-cell adhesion; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:417361 | Hs.59106 | 10668 | CGRRF1 | cell growth regulator with ring finger domain 1 | -0.857 | 0.015 | 0.322 | 27.866 | regulation of cell cycle; response to stress; cell cycle arrest; physiological process; negative regulation of cell proliferation; regulation of cell proliferation; | |
| IMAGE:755599 | Hs.458414 | 8519 | IFITM1 | interferon induced transmembrane protein 1 (9-27) | -1.289 | 0.015 | 0.446 | 27.866 | regulation of cell cycle; defense response; immune response; cell cycle; signal transduction; cell surface receptor linked signal transduction; negative regulation of cell proliferation; regulation of cell proliferation; | |
| IMAGE:1420842 | Hs.180566 | 10892 | MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | -1.627 | 0.015 | 0.554 | 27.866 | proteolysis and peptidolysis; defense response; cell communication; signal transduction; NIK-I-kappaB/NF-kappaB cascade; activation of NF-kappaB-inducing kinase; response to biotic stimulus; protein catabolism; | |
| IMAGE:701481 | Hs.926 | 4600 | MX2 | myxovirus (influenza virus) resistance 2 (mouse) | -0.828 | 0.015 | 0.154 | 30.534 | defense response; immune response; | |
| IMAGE:328889 | Hs.352898 | 4155 | HMBP | myelin A1 basic protein | -0.458 | 0.015 | 0.171 | 30.534 | defense response; immune response; synaptic transmission; neurogenesis; central nervous system development; nerve ensheathment; transmission of nerve impulse; nerve maturation; | |
| IMAGE:454296 | Hs.115515 | 50856 | CLECSF6 | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 | -0.679 | 0.298 | 0.242 | 30.534 | cell communication; cell adhesion; heterophilic cell adhesion; signal transduction; cell surface receptor linked signal transduction; humoral defense mechanism (sensu Vertebrata); cell-cell adhesion; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:746163 | Hs.414334 | 2936 | GSR | glutathione reductase | -0.344 | 1.412 | 0.251 | 30.534 | electron transport; coenzyme metabolism; glutathione metabolism; sulfur metabolism; response to stress; metabolism; response to biotic stimulus; response to pest/pathogen/parasite; | |
| IMAGE:428103 | Hs.1311 | 911 | CD1C | CD1C antigen, c polypeptide | -0.676 | 0.015 | 0.312 | 30.534 | humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:243741 | Hs.44532 | 10537 | UBD | ubiquitin D | -0.368 | 0.632 | 0.426 | 30.534 | protein modification; proteolysis and peptidolysis; humoral defense mechanism (sensu Vertebrata); protein metabolism; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); protein catabolism; | |
| IMAGE:385017 | Hs.42853 | 1388 | CREBL1 | cAMP responsive element binding protein-like 1 | -0.304 | 0.079 | 0.202 | 32.645 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; response to stress; response to unfolded protein; response to biotic stimulus; regulation of transcription; | |
| IMAGE:1324242 | Hs.99899 | 970 | TNFSF7 | tumor necrosis factor (ligand) superfamily, member 7 | -0.683 | 0.015 | 0.203 | 32.645 | apoptosis; defense response; immune response; cell communication; signal transduction; cell-cell signaling; cell growth and/or maintenance; cell proliferation; programmed cell death; | |
| IMAGE:2569884 | Hs.458355 | 716 | C1S | complement component 1, s subcomponent | -0.750 | 0.503 | 0.479 | 32.645 | proteolysis and peptidolysis; complement activation; complement activation\, classical pathway; protein catabolism; | |
| IMAGE:1558151 | Hs.41691 | 10538 | BATF | basic leucine zipper transcription factor, ATF-like | -1.974 | 0.015 | 0.179 | 34.583 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); regulation of transcription; | |
| IMAGE:814123 | Hs.196352 | 4689 | NCF4 | neutrophil cytosolic factor 4, 40kDa | -0.842 | 0.015 | 0.191 | 34.583 | electron transport; defense response; signal transduction; intracellular signaling cascade; metabolism; response to biotic stimulus; | |
| IMAGE:1571910 | Hs.110713 | 7913 | DEK | DEK oncogene (DNA binding) | -0.194 | 0.079 | 0.224 | 34.583 | regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; cotranslational membrane targeting; SRP-dependent cotranslational membrane targeting; cell communication; signal transduction; physiological process; cell growth and/or maintenance; cellular process; viral infectious cycle; viral genome replication; | |
| IMAGE:199663 | Hs.272493 | 6359 | CCL15 | chemokine (C-C motif) ligand 15 | -0.831 | 0.015 | 0.292 | 34.583 | calcium ion homeostasis; metal ion homeostasis; chemotaxis; defense response; immune response; cell communication; signal transduction; cell-cell signaling; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); di-\, tri-valent inorganic cation homeostasis; response to chemical substance; taxis; | |
| IMAGE:199663 | Hs.272493 | 6358 | CCL15 | chemokine (C-C motif) ligand 15 | -0.831 | 0.015 | 0.292 | 34.583 | calcium ion homeostasis; metal ion homeostasis; defense response; immune response; positive regulation of cell proliferation; di-\, tri-valent inorganic cation homeostasis; regulation of cell proliferation; | |
| IMAGE:1493160 | Hs.413924 | 3627 | CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.307 | 0.015 | 0.100 | 36.060 | cell motility; chemotaxis; defense response; inflammatory response; immune response; cell communication; signal transduction; cell surface receptor linked signal transduction; cell-cell signaling; muscle development; physiological process; circulation; positive regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; organogenesis; cellular process; regulation of cell proliferation; response to chemical substance; taxis; innate immune response; | |
| IMAGE:343320 | Hs.1976 | 5155 | PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | -0.841 | 0.015 | 0.243 | 36.060 | regulation of cell cycle; response to stress; cell cycle; cell growth and/or maintenance; cell proliferation; response to external stimulus; response to wounding; | |
| IMAGE:509641 | Hs.458414 | 8519 | IFITM1 | interferon induced transmembrane protein 1 (9-27) | -1.095 | 0.015 | 0.357 | 36.060 | regulation of cell cycle; defense response; immune response; cell cycle; signal transduction; cell surface receptor linked signal transduction; negative regulation of cell proliferation; regulation of cell proliferation; | |
| IMAGE:238821 | Hs.93304 | 7941 | PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.540 | 0.034 | 0.420 | 36.060 | lipid metabolism; inflammatory response; catabolism; response to wounding; response to pest/pathogen/parasite; lipid catabolism; innate immune response; | |
| IMAGE:1946534 | Hs.376208 | 4050 | LTB | lymphotoxin beta (TNF superfamily, member 3) | -1.094 | 0.015 | 0.427 | 36.060 | defense response; immune response; cell communication; signal transduction; cell-cell signaling; | |
| IMAGE:377346 | Hs.458355 | 716 | C1S | complement component 1, s subcomponent | -0.969 | 0.121 | 0.460 | 36.060 | proteolysis and peptidolysis; complement activation; complement activation\, classical pathway; protein catabolism; | |
| IMAGE:173309 | Hs.80338 | 9774 | BCLAF1 | BCL2-associated transcription factor 1 | -0.425 | 0.234 | 0.201 | 37.383 | induction of apoptosis; induction of programmed cell death; positive regulation of apoptosis; | |
| IMAGE:446927 | Hs.241570 | 7124 | TNF | tumor necrosis factor (TNF superfamily, member 2) | -2.392 | 0.015 | 0.119 | 38.650 | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; apoptosis; anti-apoptosis; defense response; inflammatory response; immune response; cell communication; heterophilic cell adhesion; leukocyte cell adhesion; signal transduction; cell-cell signaling; necrosis; pathogenesis; response to wounding; response to pest/pathogen/parasite; response to virus; programmed cell death; negative regulation of apoptosis; innate immune response; regulation of transcription; | |
| IMAGE:730149 | Hs.224397 | 6919 | TCEA2 | transcription elongation factor A (SII), 2 | -0.191 | 2.344 | 0.153 | 38.650 | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; transcription; transcription\, DNA-dependent; RNA elongation; regulation of transcription\, DNA-dependent; defense response; response to biotic stimulus; regulation of transcription; | |
| IMAGE:235155 | Hs.433300 | 2207 | FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -1.231 | 0.015 | 0.174 | 38.650 | defense response; immune response; signal transduction; cell surface receptor linked signal transduction; | |
| IMAGE:289337 | Hs.413826 | 3500 | IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) | -0.951 | 0.632 | 0.197 | 38.650 | defense response; immune response; | |
| IMAGE:289337 | Hs.413826 | 3502 | IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) | -0.951 | 0.632 | 0.197 | 38.650 | defense response; immune response; | |
| IMAGE:741977 | Hs.69771 | 629 | BF | B-factor, properdin | -1.279 | 0.015 | 0.438 | 38.650 | proteolysis and peptidolysis; complement activation; complement activation\, alternative pathway; protein catabolism; | |
| IMAGE:2514707 | Hs.197298 | 10625 | IVNS1ABP | influenza virus NS1A binding protein | -0.759 | 0.015 | 0.038 | 39.539 | transcription\, DNA-dependent; transcription from Pol III promoter; RNA processing; RNA splicing; response to pest/pathogen/parasite; response to virus; | |
| IMAGE:1527063 | Hs.169274 | 3433 | IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.934 | 0.015 | 0.146 | 39.539 | defense response; immune response; | |
| IMAGE:1870935 | Hs.418138 | 2335 | FN1 | fibronectin 1 | -1.797 | 0.015 | 0.418 | 40.492 | cell motility; response to stress; acute-phase response; immune response; cell communication; cell adhesion; response to external stimulus; response to wounding; response to pest/pathogen/parasite; cell migration; | |
| IMAGE:1422194 | Hs.511766 | 11025 | LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | -0.981 | 0.026 | 0.120 | 41.353 | defense response; immune response; | |
| IMAGE:190887 | Hs.82116 | 4615 | MYD88 | myeloid differentiation primary response gene (88) | -0.818 | 0.015 | 0.136 | 41.703 | defense response; inflammatory response; immune response; signal transduction; cell surface receptor linked signal transduction; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:703738 | Hs.914 | 3113 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -1.352 | 0.015 | 0.184 | 42.021 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:809910 | Hs.374650 | 10410 | IFITM3 | interferon induced transmembrane protein 3 (1-8U) | -0.815 | 0.034 | 0.208 | 42.021 | defense response; immune response; | |
| IMAGE:230376 | Hs.69771 | 629 | BF | B-factor, properdin | -1.402 | 0.015 | 0.317 | 42.284 | proteolysis and peptidolysis; complement activation; complement activation\, alternative pathway; protein catabolism; | |
| IMAGE:292524 | Hs.126384 | 2213 | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | -0.228 | 0.190 | 0.039 | 42.758 | defense response; immune response; cell communication; signal transduction; physiological process; cell growth and/or maintenance; cellular process; | |
| IMAGE:292524 | Hs.126384 | 9103 | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | -0.228 | 0.190 | 0.039 | 42.758 | defense response; immune response; | |
| IMAGE:487437 | Hs.110364 | 5480 | PPIC | peptidylprolyl isomerase C (cyclophilin C) | -0.165 | 0.190 | 0.144 | 42.758 | protein folding; cell communication; signal transduction; humoral defense mechanism (sensu Vertebrata); protein metabolism; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:878798 | Hs.48516 | 567 | B2M | beta-2-microglobulin | -0.903 | 0.121 | 0.187 | 42.758 | defense response; immune response; antigen presentation; antigen presentation\, endogenous antigen; antigen processing\, endogenous antigen via MHC class I; antigen processing; | |
| IMAGE:280950 | Hs.422340 | 6717 | SRI | sorcin | -0.259 | 0.234 | 0.090 | 43.039 | regulation of action potential; transport; iron ion homeostasis; intracellular iron ion storage; regulation of muscle contraction; striated muscle contraction; regulation of striated muscle contraction; intracellular signaling cascade; heart development; muscle development; circulation; regulation of heart rate; cell growth and/or maintenance; organogenesis; transmission of nerve impulse; | |
| IMAGE:855698 | Hs.351874 | 3111 | HLA-DOA | major histocompatibility complex, class II, DO alpha | -0.688 | 0.015 | 0.071 | 44.061 | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:809456 | Hs.166120 | 3665 | IRF7 | interferon regulatory factor 7 | -0.468 | 0.015 | 0.036 | 44.461 | negative regulation of transcription from Pol II promoter; transcription\, DNA-dependent; transcription initiation; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; transcription initiation from Pol II promoter; response to stress; inflammatory response; response to DNA damage stimulus; response to wounding; response to pest/pathogen/parasite; response to virus; response to endogenous stimulus; innate immune response; regulation of transcription; negative regulation of transcription\, DNA-dependent; viral induction of host immune response; passive viral induction of host immune response; | |
| IMAGE:768497 | Hs.16530 | 6362 | CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -1.506 | 0.015 | 0.210 | 44.603 | chemotaxis; defense response; inflammatory response; immune response; cell communication; signal transduction; cell-cell signaling; response to external stimulus; response to biotic stimulus; response to wounding; response to pest/pathogen/parasite; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); response to chemical substance; taxis; innate immune response; | |
| IMAGE:2239290 | Hs.436042 | 6387 | CXCL12 | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | -1.047 | 0.015 | 0.116 | 44.688 | calcium ion homeostasis; metal ion homeostasis; chemotaxis; defense response; inflammatory response; immune response; cell communication; cell adhesion; signal transduction; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; cell-cell signaling; physiological process; circulation; regulation of actin polymerization and/or depolymerization; actin polymerization and/or depolymerization; response to wounding; response to pest/pathogen/parasite; response to virus; di-\, tri-valent inorganic cation homeostasis; regulation of actin filament length; response to chemical substance; taxis; innate immune response; | |
| IMAGE:490961 | Hs.458485 | 9636 | G1P2 | interferon, alpha-inducible protein (clone IFI-15K) | -1.157 | 0.015 | 0.068 | 45.524 | defense response; immune response; cell communication; cell-cell signaling; | |
| IMAGE:77539 | Hs.10458 | 6360 | CCL16 | chemokine (C-C motif) ligand 16 | -0.268 | 0.234 | 0.048 | 45.574 | chemotaxis; defense response; inflammatory response; immune response; cell communication; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); response to chemical substance; taxis; innate immune response; | |
| IMAGE:845355 | Hs.128065 | 1075 | CTSC | cathepsin C | -0.658 | 0.015 | 0.055 | 45.659 | proteolysis and peptidolysis; defense response; immune response; protein catabolism; | |
| IMAGE:544502 | Hs.20315 | 3434 | IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.697 | 0.015 | 0.058 | 45.789 | defense response; immune response; | |
| IMAGE:269815 | Hs.727 | 3624 | INHBA | inhibin, beta A (activin A, activin AB alpha polypeptide) | -0.875 | 0.015 | 0.061 | 45.856 | regulation of cell cycle; skeletal development; ovarian follicle development; protein biosynthesis; induction of apoptosis; defense response; cell cycle arrest; cell communication; signal transduction; cell surface receptor linked signal transduction; cell-cell signaling; development; neurogenesis; mesoderm development; physiological process; cell growth and/or maintenance; female gonad development; response to external stimulus; response to biotic stimulus; organogenesis; histogenesis; cellular process; induction of programmed cell death; hemoglobin metabolism; myeloid blood cell differentiation; cell differentiation; erythrocyte differentiation; growth; negative regulation of cytokine biosynthesis; regulation of phosphorylation; negative regulation of phosphorylation; hemoglobin biosynthesis; menstrual cycle; positive regulation of apoptosis; regulation of interferon-gamma biosynthesis; negative regulation of interferon-gamma biosynthesis; regulation of B-cell differentiation; negative regulation of B-cell differentiation; negative regulation of lymphocyte differentiation; negative regulation of myeloid blood cell differentiation; regulation of macrophage differentiation; negative regulation of macrophage differentiation; negative regulation of cell cycle; negative regulation of phosphate metabolism; regulation of follicle-stimulating hormone secretion; positive regulation of follicle-stimulating hormone secretion; negative regulation of follicle-stimulating hormone secretion; positive regulation of hormone secretion; negative regulation of hormone secretion; | |
| IMAGE:2562279 | Hs.439852 | 3507 | IGHM | immunoglobulin heavy constant mu | -2.749 | 0.015 | - | - | defense response; immune response; | |
| IMAGE:344134 | Hs.348935 | 3543 | IGLL1 | immunoglobulin lambda-like polypeptide 1 | -2.572 | 0.015 | - | - | defense response; immune response; | |
| IMAGE:84295 | Hs.81134 | 3557 | IL1RN | interleukin 1 receptor antagonist | -2.058 | 0.015 | - | - | defense response; inflammatory response; immune response; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:2119876 | Hs.511796 | 1234 | CCR5 | chemokine (C-C motif) receptor 5 | -1.951 | 0.015 | - | - | chemotaxis; inflammatory response; immune response; cellular defense response; cell communication; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; response to chemical substance; taxis; innate immune response; | |
| IMAGE:855547 | Hs.308026 | 3127 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.765 | 0.015 | - | - | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:855547 | Hs.308026 | 3125 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.765 | 0.015 | - | - | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:855547 | Hs.308026 | 3126 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.765 | 0.015 | - | - | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:361323 | Hs.75256 | 5996 | RGS1 | regulator of G-protein signalling 1 | -1.763 | 0.015 | - | - | defense response; immune response; cell communication; signal transduction; G-protein signaling\, coupled to cAMP nucleotide second messenger; G-protein signaling\, adenylate cyclase inhibiting pathway; B-cell activation; lymphocyte activation; | |
| IMAGE:840942 | Hs.368409 | 3115 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | -1.761 | 0.015 | - | - | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:2443695 | Hs.308026 | 3127 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.696 | 0.015 | - | - | defense response; immune response; detection of biotic stimulus; detection of pest/pathogen/parasite; response to pest/pathogen/parasite; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:2443695 | Hs.308026 | 3125 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.696 | 0.015 | - | - | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:2443695 | Hs.308026 | 3126 | HLA-DRB3 | major histocompatibility complex, class II, DR beta 3 | -1.696 | 0.015 | - | - | defense response; immune response; cell communication; signal transduction; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:50214 | Hs.27954 | 942 | CD86 | CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) | -1.661 | 0.015 | - | - | defense response; immune response; cell communication; cell-cell signaling; positive regulation of cell proliferation; positive regulation of cytokine biosynthesis; T-cell activation; regulation of cell proliferation; regulation of tumor necrosis factor-beta biosynthesis; positive regulation of tumor necrosis factor-beta biosynthesis; regulation of interleukin-2 biosynthesis; positive regulation of interleukin-2 biosynthesis; regulation of interleukin-4 biosynthesis; positive regulation of interleukin-4 biosynthesis; regulation of transcription; positive regulation of T-helper cell differentiation; regulation of T-helper 2 cell differentiation; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription; lymphocyte activation; | |
| IMAGE:433567 | Hs.105806 | 10578 | GNLY | granulysin | -1.645 | 0.015 | - | - | xenobiotic metabolism; defense response; immune response; cellular defense response; metabolism; response to xenobiotic stimulus; response to wounding; response to pest/pathogen/parasite; response to fungi; defense response to fungi; | |
| IMAGE:377560 | Hs.95327 | 915 | CD3D | CD3D antigen, delta polypeptide (TiT3 complex) | -1.554 | 0.015 | - | - | protein complex assembly; signal transduction; cell surface receptor linked signal transduction; protein metabolism; T-cell activation; positive thymic T-cell selection; thymic T-cell selection; lymphocyte activation; | |
| IMAGE:2306953 | Hs.69328 | 23643 | LY96 | lymphocyte antigen 96 | -1.479 | 0.015 | - | - | inflammatory response; immune response; cellular defense response; signal transduction; cell surface receptor linked signal transduction; response to wounding; response to pest/pathogen/parasite; antibacterial humoral response; antibacterial humoral response (sensu Vertebrata); antimicrobial humoral response (sensu Vertebrata); innate immune response; | |
| IMAGE:1670188 | Hs.2200 | 5551 | PRF1 | perforin 1 (pore forming protein) | -1.417 | 0.015 | - | - | apoptosis; programmed cell death\, virus-infected cells; programmed cell death\, transformed cells; immune response; cellular defense response; pathogenesis; response to wounding; response to pest/pathogen/parasite; hemolysis; | |
| IMAGE:1459376 | Hs.112405 | 6280 | S100A9 | S100 calcium binding protein A9 (calgranulin B) | -1.404 | 0.015 | - | - | inflammatory response; cell communication; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:845477 | Hs.196384 | 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -1.384 | 0.015 | - | - | prostaglandin biosynthesis; cell motility; inflammatory response; physiological process; biological_process; cellular process; arachidonic acid metabolism; cyclooxygenase pathway; regulation of innate immune response; regulation of inflammatory response; | |
| IMAGE:562729 | Hs.416073 | 6279 | S100A8 | S100 calcium binding protein A8 (calgranulin A) | -1.366 | 0.015 | - | - | inflammatory response; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:742132 | Hs.458485 | 9636 | G1P2 | interferon, alpha-inducible protein (clone IFI-15K) | -1.288 | 0.015 | - | - | defense response; immune response; cell communication; cell-cell signaling; | |
| IMAGE:1689083 | Hs.1987 | 940 | CD28 | CD28 antigen (Tp44) | -1.250 | 0.015 | - | - | protein biosynthesis; regulation of protein biosynthesis; immune response; humoral immune response; signal transduction; cell surface receptor linked signal transduction; response to pest/pathogen/parasite; positive regulation of biosynthesis; cytokine biosynthesis; positive regulation of T-cell proliferation; cytokine metabolism; regulation of T-cell proliferation; regulation of viral genome replication; positive regulation of viral genome replication; positive regulation of protein biosynthesis; regulation of anti-apoptosis; positive regulation of anti-apoptosis; positive regulation of lymphocyte proliferation; | |
| IMAGE:153340 | Hs.75765 | 2920 | CXCL2 | chemokine (C-X-C motif) ligand 2 | -1.246 | 0.015 | - | - | chemotaxis; defense response; inflammatory response; immune response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; response to wounding; response to pest/pathogen/parasite; response to chemical substance; taxis; innate immune response; | |
| IMAGE:489794 | Hs.283022 | 54210 | TREM1 | triggering receptor expressed on myeloid cells 1 | -1.169 | 0.015 | - | - | immune response; humoral immune response; signal transduction; intracellular signaling cascade; response to pest/pathogen/parasite; | |
| IMAGE:713129 | Hs.90708 | 3001 | GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -1.119 | 0.015 | - | - | proteolysis and peptidolysis; apoptosis; defense response; immune response; cell death; programmed cell death; cytolysis; protein catabolism; | |
| IMAGE:590154 | Hs.179657 | 5329 | PLAUR | plasminogen activator, urokinase receptor | -1.080 | 0.015 | - | - | chemotaxis; signal transduction; cell surface receptor linked signal transduction; blood coagulation; hemostasis; response to chemical substance; taxis; coagulation; | |
| IMAGE:588915 | Hs.278613 | 3429 | IFI27 | interferon, alpha-inducible protein 27 | -1.053 | 0.015 | - | - | defense response; immune response; | |
| IMAGE:1486083 | Hs.1722 | 3552 | IL1A | interleukin 1, alpha | -1.050 | 0.015 | - | - | regulation of cell cycle; apoptosis; anti-apoptosis; chemotaxis; defense response; inflammatory response; immune response; cell cycle; cell communication; cell-cell signaling; cell growth and/or maintenance; cell proliferation; negative regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; programmed cell death; regulation of cell proliferation; response to chemical substance; taxis; negative regulation of apoptosis; innate immune response; | |
| IMAGE:681906 | Hs.1422 | 2268 | FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | -1.030 | 0.015 | - | - | protein modification; protein amino acid phosphorylation; signal transduction; intracellular signaling cascade; physiological process; cell growth and/or maintenance; response to pest/pathogen/parasite; response to virus; cellular process; phosphorylation; | |
| IMAGE:450060 | Hs.296941 | 3078 | HFL1 | H factor (complement)-like 1 | -1.025 | 0.015 | - | - | complement activation; humoral defense mechanism (sensu Vertebrata); | |
| IMAGE:472008 | Hs.301921 | 1230 | CCR1 | chemokine (C-C motif) receptor 1 | -0.980 | 0.015 | - | - | chemotaxis; defense response; inflammatory response; immune response; cell communication; cell adhesion; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to cyclic nucleotide second messenger; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; cyclic-nucleotide-mediated signaling; response to chemical substance; taxis; innate immune response; | |
| IMAGE:80633 | Hs.519033 | 7097 | TLR2 | toll-like receptor 2 | -0.946 | 0.015 | - | - | defense response; inflammatory response; immune response; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:809598 | Hs.409934 | 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | -0.935 | 0.015 | - | - | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:151201 | Hs.100194 | 241 | ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.884 | 0.015 | - | - | leukotriene metabolism; inflammatory response; response to wounding; response to pest/pathogen/parasite; leukotriene biosynthesis; innate immune response; icosanoid biosynthesis; | |
| IMAGE:1569006 | Hs.27954 | 942 | CD86 | CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) | -0.868 | 0.015 | - | - | defense response; immune response; cell communication; cell-cell signaling; positive regulation of cell proliferation; positive regulation of cytokine biosynthesis; T-cell activation; regulation of cell proliferation; regulation of tumor necrosis factor-beta biosynthesis; positive regulation of tumor necrosis factor-beta biosynthesis; regulation of interleukin-2 biosynthesis; positive regulation of interleukin-2 biosynthesis; regulation of interleukin-4 biosynthesis; positive regulation of interleukin-4 biosynthesis; regulation of transcription; positive regulation of T-helper cell differentiation; regulation of T-helper 2 cell differentiation; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription; lymphocyte activation; | |
| IMAGE:884663 | Hs.487662 | 9734 | HDAC9 | histone deacetylase 9 | -0.860 | 0.015 | - | - | regulation of cell cycle; establishment and/or maintenance of chromatin architecture; transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; protein amino acid deacetylation; inflammatory response; cell cycle; response to wounding; response to pest/pathogen/parasite; regulation of myogenesis; chromatin modification; histone modification; histone deacetylation; lymphocyte differentiation; B-cell differentiation; B-cell activation; innate immune response; regulation of transcription; negative regulation of myogenesis; | |
| IMAGE:814251 | Hs.32970 | 6504 | SLAMF1 | signaling lymphocytic activation molecule family member 1 | -0.842 | 0.015 | - | - | positive regulation of cell proliferation; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); regulation of cell proliferation; | |
| IMAGE:491763 | Hs.126256 | 3553 | IL1B | interleukin 1, beta | -0.754 | 0.015 | - | - | regulation of cell cycle; apoptosis; defense response; inflammatory response; immune response; cell cycle; cell communication; signal transduction; cell-cell signaling; cell growth and/or maintenance; cell proliferation; negative regulation of cell proliferation; response to wounding; response to pest/pathogen/parasite; programmed cell death; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); regulation of cell proliferation; innate immune response; | |
| IMAGE:505881 | Hs.407135 | 100 | ADA | adenosine deaminase | -0.754 | 0.015 | - | - | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; nucleotide metabolism; purine nucleoside monophosphate biosynthesis; purine ribonucleotide biosynthesis; ribonucleoside monophosphate biosynthesis; purine ribonucleoside monophosphate metabolism; purine ribonucleoside monophosphate biosynthesis; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:739094 | Hs.371264 | 25939 | SAMHD1 | SAM domain and HD domain 1 | -0.750 | 0.015 | - | - | defense response; immune response; response to pest/pathogen/parasite; response to virus; | |
| IMAGE:898221 | Hs.82120 | 4929 | NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.740 | 0.015 | - | - | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; cell communication; signal transduction; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); regulation of transcription; | |
| IMAGE:2516692 | Hs.416848 | 1521 | CTSW | cathepsin W (lymphopain) | -0.731 | 0.015 | - | - | proteolysis and peptidolysis; defense response; immune response; protein catabolism; | |
| IMAGE:1455976 | Hs.174195 | 10581 | IFITM2 | interferon induced transmembrane protein 2 (1-8D) | -0.681 | 0.015 | - | - | defense response; immune response; | |
| IMAGE:35503 | Hs.97199 | 22918 | C1QR1 | complement component 1, q subcomponent, receptor 1 | -0.672 | 0.015 | - | - | inflammatory response; heterophilic cell adhesion; cell-cell adhesion; macrophage activation; immune cell activation; | |
| IMAGE:756708 | Hs.10082 | 3783 | KCNN4 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | -0.659 | 0.015 | - | - | transport; ion transport; potassium ion transport; defense response; response to biotic stimulus; monovalent inorganic cation transport; metal ion transport; | |
| IMAGE:1475574 | Hs.173894 | 1435 | CSF1 | colony stimulating factor 1 (macrophage) | -0.655 | 0.015 | - | - | development; cell growth and/or maintenance; cell proliferation; positive regulation of cell proliferation; organogenesis; cellular process; hemopoiesis; myeloid blood cell differentiation; cell differentiation; macrophage differentiation; regulation of cell proliferation; | |
| IMAGE:346360 | Hs.498997 | 27040 | LAT | linker for activation of T cells | -0.600 | 0.015 | - | - | defense response; immune response; cell communication; signal transduction; | |
| IMAGE:117806 | Hs.381568 | 3512 | IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | -0.566 | 0.015 | - | - | defense response; immune response; | |
| IMAGE:1588600 | Hs.409934 | 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | -0.564 | 0.015 | - | - | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:2420963 | Hs.511766 | 11025 | LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | -0.558 | 0.015 | - | - | defense response; immune response; | |
| IMAGE:1591736 | Hs.386748 | 2206 | MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | -0.558 | 0.015 | - | - | immune response; humoral immune response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; cell growth and/or maintenance; cell proliferation; response to pest/pathogen/parasite; | |
| IMAGE:2576857 | Hs.150580 | 10209 | SUI1 | putative translation initiation factor | -0.548 | 0.015 | - | - | protein biosynthesis; translational initiation; regulation of protein biosynthesis; regulation of translation; regulation of translational initiation; response to stress; physiological process; cell growth and/or maintenance; regulation of biosynthesis; cellular process; translation; | |
| IMAGE:246120 | Hs.20521 | 3276 | HRMT1L2 | HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae) | -0.532 | 0.015 | - | - | protein amino acid methylation; defense response; signal transduction; cell surface receptor linked signal transduction; protein amino acid alkylation; response to biotic stimulus; | |
| IMAGE:187614 | Hs.388294 | 4086 | MADH1 | MAD, mothers against decapentaplegic homolog 1 (Drosophila) | -0.525 | 0.015 | - | - | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; cell communication; signal transduction; transmembrane receptor protein serine/threonine kinase signaling pathway; transforming growth factor beta receptor signaling pathway; regulation of transcription; | |
| IMAGE:215000 | Hs.348500 | 7433 | VIPR1 | vasoactive intestinal peptide receptor 1 | -0.479 | 0.015 | - | - | cell motility; muscle contraction; defense response; immune response; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to cyclic nucleotide second messenger; synaptic transmission; physiological process; digestion; positive regulation of cell proliferation; transmission of nerve impulse; cyclic-nucleotide-mediated signaling; regulation of cell proliferation; | |
| IMAGE:530185 | Hs.79197 | 9308 | CD83 | CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) | -0.350 | 0.015 | - | - | defense response; immune response; humoral immune response; cell communication; signal transduction; response to biotic stimulus; response to pest/pathogen/parasite; | |
| IMAGE:1636156 | Hs.377097 | 84166 | NOD27 | nucleotide-binding oligomerization domains 27 | -0.320 | 0.015 | - | - | defense response; response to biotic stimulus; response to pathogen; defense response to pathogen; | |
| IMAGE:2490680 | Hs.407442 | 6965 | TRGV9 | T cell receptor gamma variable 9 | -0.735 | 0.026 | - | - | defense response; immune response; | |
| IMAGE:810242 | Hs.155935 | 719 | C3AR1 | complement component 3a receptor 1 | -0.556 | 0.026 | - | - | cell motility; chemotaxis; muscle contraction; smooth muscle contraction; inflammatory response; immune response; cellular defense response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; physiological process; circulation; response to wounding; response to pest/pathogen/parasite; cellular process; response to chemical substance; taxis; innate immune response; | |
| IMAGE:46213 | Hs.110713 | 7913 | DEK | DEK oncogene (DNA binding) | -0.436 | 0.026 | - | - | regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; cotranslational membrane targeting; SRP-dependent cotranslational membrane targeting; cell communication; signal transduction; physiological process; cell growth and/or maintenance; cellular process; viral infectious cycle; viral genome replication; | |
| IMAGE:767176 | Hs.54673 | 8741 | TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | -0.404 | 0.026 | - | - | defense response; immune response; cell communication; signal transduction; positive regulation of cell proliferation; regulation of cell proliferation; | |
| IMAGE:258860 | Hs.387679 | 3117 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.369 | 0.026 | - | - | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; regulation of transcription; | |
| IMAGE:123730 | Hs.411942 | 8631 | SCAP1 | src family associated phosphoprotein 1 | -0.166 | 0.026 | - | - | defense response; immune response; cell communication; signal transduction; | |
| IMAGE:289496 | Hs.169274 | 3433 | IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.718 | 0.034 | - | - | defense response; immune response; | |
| IMAGE:2458975 | Hs.727 | 3624 | INHBA | inhibin, beta A (activin A, activin AB alpha polypeptide) | -0.659 | 0.034 | - | - | regulation of cell cycle; skeletal development; ovarian follicle development; protein biosynthesis; induction of apoptosis; defense response; cell cycle arrest; cell communication; signal transduction; cell surface receptor linked signal transduction; cell-cell signaling; development; neurogenesis; mesoderm development; physiological process; cell growth and/or maintenance; female gonad development; response to external stimulus; response to biotic stimulus; organogenesis; histogenesis; cellular process; induction of programmed cell death; hemoglobin metabolism; myeloid blood cell differentiation; cell differentiation; erythrocyte differentiation; growth; negative regulation of cytokine biosynthesis; regulation of phosphorylation; negative regulation of phosphorylation; hemoglobin biosynthesis; menstrual cycle; positive regulation of apoptosis; regulation of interferon-gamma biosynthesis; negative regulation of interferon-gamma biosynthesis; regulation of B-cell differentiation; negative regulation of B-cell differentiation; negative regulation of lymphocyte differentiation; negative regulation of myeloid blood cell differentiation; regulation of macrophage differentiation; negative regulation of macrophage differentiation; negative regulation of cell cycle; negative regulation of phosphate metabolism; regulation of follicle-stimulating hormone secretion; positive regulation of follicle-stimulating hormone secretion; negative regulation of follicle-stimulating hormone secretion; positive regulation of hormone secretion; negative regulation of hormone secretion; | |
| IMAGE:1634832 | Hs.132781 | 9466 | IL27RA | interleukin 27 receptor, alpha | -0.537 | 0.034 | - | - | defense response; immune response; signal transduction; cell surface receptor linked signal transduction; | |
| IMAGE:2550047 | Hs.20315 | 3434 | IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.407 | 0.079 | - | - | defense response; immune response; | |
| IMAGE:447509 | Hs.351874 | 3111 | HLA-DOA | major histocompatibility complex, class II, DO alpha | -0.948 | 0.083 | - | - | defense response; immune response; antigen presentation; antigen presentation\, exogenous antigen; antigen processing\, exogenous antigen via MHC class II; antigen processing; | |
| IMAGE:825330 | Hs.199248 | 5734 | PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.527 | 0.083 | - | - | defense response; immune response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to cyclic nucleotide second messenger; G-protein signaling\, coupled to cAMP nucleotide second messenger; cAMP-mediated signaling; | |
| IMAGE:767765 | Hs.79022 | 2669 | GEM | GTP binding protein overexpressed in skeletal muscle | -0.781 | 0.121 | - | - | defense response; immune response; signal transduction; cell surface receptor linked signal transduction; intracellular signaling cascade; small GTPase mediated signal transduction; physiological process; cell growth and/or maintenance; cellular process; | |
| IMAGE:853456 | Hs.109058 | 9252 | RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.462 | 0.121 | - | - | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; protein amino acid phosphorylation; response to stress; transmembrane receptor protein tyrosine kinase signaling pathway; epidermal growth factor receptor signaling pathway; intracellular signaling cascade; protein kinase cascade; physiological process; response to external stimulus; response to abiotic stimulus; histone modification; histone phosphorylation; response to chemical substance; regulation of transcription; | |
| IMAGE:884606 | Hs.6019 | 5611 | DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.312 | 0.121 | - | - | regulation of translation; defense response; response to biotic stimulus; translation; | |
| IMAGE:1159963 | Hs.166120 | 3665 | IRF7 | interferon regulatory factor 7 | -0.847 | 0.154 | - | - | negative regulation of transcription from Pol II promoter; transcription\, DNA-dependent; transcription initiation; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; transcription initiation from Pol II promoter; response to stress; inflammatory response; response to DNA damage stimulus; response to wounding; response to pest/pathogen/parasite; response to virus; response to endogenous stimulus; innate immune response; regulation of transcription; negative regulation of transcription\, DNA-dependent; viral induction of host immune response; passive viral induction of host immune response; | |
| IMAGE:2392841 | Hs.159543 | 8698 | EDG6 | endothelial differentiation, G-protein-coupled receptor 6 | -0.286 | 0.154 | - | - | defense response; immune response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); phospholipase C activation; cytosolic calcium ion concentration elevation; | |
| IMAGE:327079 | Hs.177136 | 944 | TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | -0.751 | 0.190 | - | - | induction of apoptosis; defense response; immune response; cell communication; signal transduction; cell-cell signaling; cell growth and/or maintenance; cell proliferation; induction of programmed cell death; positive regulation of apoptosis; | |
| IMAGE:2556649 | Hs.18858 | 8605 | PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | -0.545 | 0.190 | - | - | fatty acid metabolism; glycerophospholipid metabolism; inflammatory response; signal transduction; intracellular signaling cascade; parturition; physiological process; phospholipid catabolism; response to wounding; response to pest/pathogen/parasite; arachidonic acid metabolism; innate immune response; glycerophospholipid catabolism; | |
| IMAGE:138369 | Hs.126384 | 2213 | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | -0.756 | 0.234 | - | - | defense response; immune response; cell communication; signal transduction; physiological process; cell growth and/or maintenance; cellular process; | |
| IMAGE:138369 | Hs.126384 | 9103 | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor for (CD32) | -0.756 | 0.234 | - | - | defense response; immune response; | |
| IMAGE:624361 | Hs.170087 | 196 | AHR | aryl hydrocarbon receptor | -0.380 | 0.234 | - | - | transcription\, DNA-dependent; regulation of transcription\, DNA-dependent; transcription from Pol II promoter; apoptosis; response to stress; cell cycle; cell communication; signal transduction; physiological process; cell proliferation; response to xenobiotic stimulus; programmed cell death; response to chemical substance; regulation of transcription; | |
| IMAGE:488751 | Hs.511916 | 2029 | ENSA | endosulfine alpha | -0.285 | 0.298 | - | - | transport; response to nutrients; cell growth and/or maintenance; response to extracellular stimulus; response to chemical substance; | |
| IMAGE:485989 | Hs.251526 | 6354 | CCL7 | chemokine (C-C motif) ligand 7 | -0.798 | 0.503 | - | - | calcium ion homeostasis; metal ion homeostasis; chemotaxis; defense response; inflammatory response; immune response; cell communication; signal transduction; cell-cell signaling; response to wounding; response to pest/pathogen/parasite; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); di-\, tri-valent inorganic cation homeostasis; response to chemical substance; taxis; innate immune response; | |
| IMAGE:853906 | Hs.181244 | 3105 | HLA-A | major histocompatibility complex, class I, A | -0.568 | 0.503 | - | - | defense response; immune response; antigen presentation; antigen presentation\, endogenous antigen; antigen processing\, endogenous antigen via MHC class I; antigen processing; | |
| IMAGE:841008 | Hs.62661 | 2633 | GBP1 | guanylate binding protein 1, interferon-inducible, 67kDa | -0.271 | 0.503 | - | - | defense response; immune response; | |
| IMAGE:1675957 | Hs.54517 | 2220 | FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) | -0.156 | 0.503 | - | - | phagocytosis; heterophilic cell adhesion; opsonization; humoral defense mechanism (sensu Vertebrata); cell-cell adhesion; antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:450193 | Hs.58831 | 9214 | TOSO | regulator of Fas-induced apoptosis | -0.537 | 0.632 | - | - | anti-apoptosis; immune response; cellular defense response; response to wounding; response to pest/pathogen/parasite; negative regulation of apoptosis; | |
| IMAGE:1456757 | Hs.201300 | 10800 | CYSLTR1 | cysteinyl leukotriene receptor 1 | -0.501 | 0.632 | - | - | defense response; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway; G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating); cytosolic calcium ion concentration elevation; physiological process; respiratory gaseous exchange; response to biotic stimulus; | |
| IMAGE:2049835 | Hs.440898 | 2219 | FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.577 | 1.412 | - | - | phagocytosis; heterophilic cell adhesion; opsonization; cell-cell adhesion; | |
| IMAGE:269269 | Hs.342874 | 7049 | TGFBR3 | transforming growth factor, beta receptor III (betaglycan, 300kDa) | -0.337 | 1.412 | - | - | cell communication; signal transduction; transmembrane receptor protein serine/threonine kinase signaling pathway; transforming growth factor beta receptor signaling pathway; development; biological_process; | |
| IMAGE:450358 | Hs.181244 | 3105 | HLA-A | major histocompatibility complex, class I, A | -0.298 | 1.412 | - | - | defense response; immune response; antigen presentation; antigen presentation\, endogenous antigen; antigen processing\, endogenous antigen via MHC class I; antigen processing; | |
| IMAGE:771240 | Hs.54673 | 8741 | TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | -0.207 | 1.412 | - | - | defense response; immune response; cell communication; signal transduction; positive regulation of cell proliferation; regulation of cell proliferation; | |
| IMAGE:589630 | Hs.444105 | 953 | ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.486 | 2.344 | - | - | cell communication; cell adhesion; cell-cell signaling; blood coagulation; hemostasis; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); coagulation; | |
| IMAGE:840460 | Hs.362807 | 3575 | IL7R | interleukin 7 receptor | -0.455 | 2.344 | - | - | regulation of DNA recombination; DNA recombination; defense response; immune response; signal transduction; cell surface receptor linked signal transduction; humoral defense mechanism (sensu Vertebrata); antimicrobial humoral response; antimicrobial humoral response (sensu Vertebrata); | |
| IMAGE:811015 | Hs.25647 | 2353 | FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | -0.414 | 2.344 | - | - | DNA alkylation; DNA methylation; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; transcription from Pol II promoter; inflammatory response; physiological process; cell growth and/or maintenance; response to wounding; response to pest/pathogen/parasite; cellular process; regulation of gene expression\, epigenetic; innate immune response; | |
| IMAGE:1622149 | Hs.105407 | 1896 | ED1 | ectodermal dysplasia 1, anhidrotic | -0.287 | 2.344 | - | - | defense response; immune response; cell communication; signal transduction; development; ectoderm development; morphogenesis; histogenesis; cellular process; cell differentiation; | |
| IMAGE:1967591 | Hs.87205 | 4064 | LY64 | lymphocyte antigen 64 homolog, radioprotective 105kDa (mouse) | -0.252 | 2.344 | - | - | defense response; inflammatory response; immune response; response to wounding; response to pest/pathogen/parasite; innate immune response; | |
| IMAGE:135941 | Hs.24640 | 8482 | SEMA7A | sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A | -0.187 | 2.344 | - | - | defense response; immune response; development; neurogenesis; biological_process; organogenesis; |