SVF Genes - GO Cellular Component Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Cellular Component)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Cellular Component)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.10E-16 3 363 1500 1256 7420 3.10E-16
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005576 extracellular region 1 181 1500 555 7420 5.83E-13
GO:0005887 integral to plasma membrane 8 196 1500 738 7420 6.92E-06
GO:0031226 intrinsic to plasma membrane 16 167 1500 642 7420 1.18E-04
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.37E-07 3 41 1500 93 7420 1.37E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005764 lysosome 5 37 1500 87 7420 1.63E-06
GO:0000323 lytic vacuole 6 35 1500 81 7420 1.99E-06
GO:0005885 Arp2/3 protein complex 28 4 1500 6 7420 1.76E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
9.63E-07 4 68 1500 195 7420 9.63E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0031012 extracellular matrix 4 51 1500 125 7420 9.23E-08
GO:0005578 extracellular matrix (sensu Metazoa) 11 60 1500 183 7420 3.61E-05
GO:0009897 external side of plasma membrane 30 4 1500 6 7420 1.76E-02
GO:0005945 6-phosphofructokinase complex 43 2 1500 2 7420 4.08E-02
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.04E-06 3 188 1500 691 7420 2.04E-06
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005615 extracellular space 2 88 1500 254 7420 3.41E-08
GO:0000267 cell fraction 35 112 1500 470 7420 2.68E-02
GO:0005625 soluble fraction 45 39 1500 150 7420 4.96E-02
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.74E-06 2 24 1500 48 7420 3.74E-06
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0043235 receptor complex 7 24 1500 48 7420 3.74E-06
GO:0008305 integrin complex 18 14 1500 28 7420 4.08E-04
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
6.34E-05 3 517 1500 2251 7420 6.34E-05
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005886 plasma membrane 9 113 1500 385 7420 7.34E-06
GO:0016021 integral to membrane 17 482 1500 2104 7420 1.77E-04
GO:0031224 intrinsic to membrane 32 338 1500 1527 7420 2.03E-02
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
8.34E-05 2 8 1500 10 7420 8.34E-05
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0001772 immunological synapse 13 8 1500 10 7420 8.34E-05
GO:0042101 T cell receptor complex 22 5 1500 7 7420 4.89E-03
 
 
 
Cluster 8 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.89E-04 2 643 1500 2890 7420 2.89E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0016020 membrane 10 593 1500 2601 7420 2.96E-05
GO:0005623 cell 31 550 1500 2551 7420 2.01E-02
 
 
 
Cluster 9 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.15E-04 4 45 1500 137 7420 3.15E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005830 cytosolic ribosome (sensu Eukaryota) 3 18 1500 26 7420 8.54E-08
GO:0016282 eukaryotic 43S preinitiation complex 19 10 1500 17 7420 5.31E-04
GO:0005840 ribosome 23 36 1500 118 7420 4.94E-03
GO:0008290 F-actin capping protein complex 29 4 1500 6 7420 1.76E-02
 
 
 
Cluster 10 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.87E-04 4 18 1500 41 7420 4.87E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030173 integral to Golgi membrane 26 12 1500 31 7420 1.37E-02
GO:0031228 intrinsic to Golgi membrane 27 13 1500 35 7420 1.53E-02
GO:0016605 PML body 37 3 1500 4 7420 2.80E-02
GO:0005602 complement component C1q complex 41 2 1500 2 7420 4.08E-02
 
 
 
Cluster 11 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.05E-03 2 11 1500 21 7420 1.05E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005842 cytosolic large ribosomal subunit (sensu Eukaryota) 12 11 1500 17 7420 8.20E-05
GO:0015934 large ribosomal subunit 20 11 1500 21 7420 1.05E-03
 
 
 
Cluster 12 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.58E-03 3 9 1500 16 7420 1.58E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0016283 eukaryotic 48S initiation complex 15 7 1500 8 7420 8.99E-05
GO:0005843 cytosolic small ribosomal subunit (sensu Eukaryota) 14 7 1500 8 7420 8.99E-05
GO:0015935 small ribosomal subunit 21 9 1500 16 7420 1.58E-03
 
 
 
Cluster 13 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
6.57E-03 3 10 1500 22 7420 6.57E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005581 collagen 39 8 1500 20 7420 3.39E-02
GO:0005583 fibrillar collagen 40 5 1500 10 7420 3.41E-02
GO:0005791 rough endoplasmic reticulum 42 2 1500 2 7420 4.08E-02
 
 
 
Cluster 14 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
8.25E-03 2 3 1500 3 7420 8.25E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0043205 fibril 25 3 1500 3 7420 8.25E-03
GO:0001527 microfibril 24 3 1500 3 7420 8.25E-03
 
 
 
Cluster 15 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.03E-02 2 6 1500 12 7420 2.03E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0042612 MHC class I protein complex 34 6 1500 12 7420 2.03E-02
GO:0042611 MHC protein complex 33 6 1500 12 7420 2.03E-02
 
 
 
Cluster 16 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.80E-02 2 3 1500 4 7420 2.80E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0031229 intrinsic to nuclear inner membrane 38 3 1500 4 7420 2.80E-02
GO:0005639 integral to nuclear inner membrane 36 3 1500 4 7420 2.80E-02
 
 
 
Cluster 17 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.08E-02 1 2 1500 2 7420 4.08E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0042824 MHC class I peptide loading complex 44 2 1500 2 7420 4.08E-02