Adipocytes Genes - GO Biological Process Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Biological Process)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Biological Process)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.93E-08 3 19 2018 23 7792 1.93E-08
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 3 14 2018 17 7792 1.76E-06
GO:0042775 ATP synthesis coupled electron transport (sensu Eukaryota) 4 15 2018 19 7792 1.96E-06
GO:0030516 regulation of axon extension 24 4 2018 4 7792 4.49E-03
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.80E-08 6 150 2018 393 7792 2.80E-08
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006092 main pathways of carbohydrate metabolism 5 32 2018 59 7792 3.14E-06
GO:0007582 physiological process 12 95 2018 266 7792 2.01E-04
GO:0008152 metabolism 13 104 2018 299 7792 3.20E-04
GO:0051262 protein tetramerization 50 5 2018 7 7792 1.50E-02
GO:0042770 DNA damage response, signal transduction 51 7 2018 12 7792 1.73E-02
GO:0016126 sterol biosynthesis 65 10 2018 21 7792 2.61E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.96E-07 6 110 2018 281 7792 4.96E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006631

fatty acid metabolism

 6 41 2018 84 7792 4.95E-06
GO:0044255 cellular lipid metabolism 11 42 2018 94 7792 5.69E-05
GO:0006100 tricarboxylic acid cycle intermediate metabolism 38 8 2018 13 7792 7.08E-03
GO:0019752 carboxylic acid metabolism 40 36 2018 98 7792 1.12E-02
GO:0006379 mRNA cleavage 55 4 2018 5 7792 1.78E-02
GO:0030036 actin cytoskeleton organization and biogenesis 60 31 2018 85 7792 1.98E-02
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
6.40E-07 6 41 2018 79 7792 6.40E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0046394 carboxylic acid biosynthesis 15 16 2018 31 7792 1.91E-03
GO:0006633 fatty acid biosynthesis 19 14 2018 27 7792 3.44E-03
GO:0051090 regulation of transcription factor activity 54 3 2018 3 7792 1.74E-02
GO:0051649 establishment of cellular localization 67 7 2018 13 7792 2.92E-02
GO:0019318 hexose metabolism 77 12 2018 28 7792 3.78E-02
GO:0046822 regulation of nucleocytoplasmic transport 83 4 2018 6 7792 4.25E-02
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
7.11E-07 4 380 2018 1201 7792 7.11E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006091 generation of precursor metabolites and energy 1 109 2018 268 7792 5.55E-08
GO:0006810 transport 7 331 2018 1057 7792 1.23E-05
GO:0006118 electron transport 10 86 2018 224 7792 2.10E-05
GO:0044237 cellular metabolism 16 61 2018 170 7792 2.31E-03
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.59E-06 3 19 2018 27 7792 1.59E-06
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0009060 aerobic respiration 2 19 2018 27 7792 1.59E-06
GO:0006099 tricarboxylic acid cycle 8 15 2018 21 7792 1.58E-05
GO:0046356 acetyl-CoA catabolism 9 15 2018 21 7792 1.58E-05
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.31E-05 5 56 2018 132 7792 2.31E-05
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0045045 secretory pathway 18 43 2018 113 7792 2.83E-03
GO:0051291 protein heterooligomerization 25 4 2018 4 7792 4.49E-03
GO:0048193 Golgi vesicle transport 30 32 2018 81 7792 4.84E-03
GO:0006887 exocytosis 45 19 2018 45 7792 1.23E-02
GO:0006888 ER to Golgi vesicle-mediated transport 63 22 2018 57 7792 2.36E-02
 
 
 
Cluster 8 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.21E-04 4 153 2018 457 7792 1.21E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0015031 protein transport 26 113 2018 352 7792 4.55E-03
GO:0045184 establishment of protein localization 39 80 2018 243 7792 7.86E-03
GO:0006886 intracellular protein transport 41 57 2018 168 7792 1.18E-02
GO:0007017 microtubule-based process 48 29 2018 77 7792 1.49E-02
 
 
 
Cluster 9 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.59E-04 5 31 2018 69 7792 4.59E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006417

regulation of protein biosynthesis

 36 16 2018 34 7792 6.21E-03
GO:0017148 negative regulation of protein biosynthesis 44 6 2018 9 7792 1.20E-02
GO:0009083 branched chain family amino acid catabolism 49 5 2018 7 7792 1.50E-02
GO:0045947 negative regulation of translational initiation 59 4 2018 5 7792 1.78E-02
GO:0006445 regulation of translation 64 20 2018 51 7792 2.51E-02
 
 
 
Cluster 10 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
5.59E-04 4 28 2018 61 7792 5.59E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006979 response to oxidative stress 29 17 2018 36 7792 4.63E-03
GO:0007040 lysosome organization and biogenesis 57 4 2018 5 7792 1.78E-02
GO:0006800 oxygen and reactive oxygen species metabolism 66 16 2018 39 7792 2.77E-02
GO:0008104 protein localization 78 6 2018 11 7792 4.03E-02
 
 
 
Cluster 11 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
7.55E-04 3 14 2018 24 7792 7.55E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030163 protein catabolism 21 10 2018 17 7792 4.06E-03
GO:0043285 biopolymer catabolism 46 8 2018 14 7792 1.28E-02
GO:0006282 regulation of DNA repair 82 4 2018 6 7792 4.25E-02
 
 
 
Cluster 12 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.34E-03 4 20 2018 41 7792 1.34E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006725 aromatic compound metabolism 47 11 2018 22 7792 1.30E-02
GO:0006558 L-phenylalanine metabolism 68 5 2018 8 7792 3.16E-02
GO:0006559 L-phenylalanine catabolism 69 5 2018 8 7792 3.16E-02
GO:0006732 coenzyme metabolism 84 7 2018 14 7792 4.56E-02
 
 
 
Cluster 13 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.62E-03 2 15 2018 28 7792 1.62E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0009416 response to light stimulus 34 5 2018 6 7792 5.46E-03
GO:0007265 Ras protein signal transduction 76 10 2018 22 7792 3.70E-02
 
 
 
Cluster 14 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.74E-03 4 13 2018 23 7792 1.74E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0007007 inner mitochondrial membrane organization and biogenesis 32 5 2018 6 7792 5.46E-03
GO:0045039 protein import into mitochondrial inner membrane 58 4 2018 5 7792 1.78E-02
GO:0006626 protein targeting to mitochondrion 71 8 2018 16 7792 3.31E-02
GO:0000209 protein polyubiquitination 81 4 2018 6 7792 4.25E-02
 
 
 
Cluster 15 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.39E-03 2 18 2018 37 7792 2.39E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006096 glycolysis 20 15 2018 30 7792 3.91E-03
GO:0006007 glucose catabolism 35 16 2018 34 7792 6.21E-03
 
 
 
Cluster 16 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.57E-03 2 118 2018 367 7792 3.57E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006629 lipid metabolism 14 64 2018 173 7792 7.49E-04
GO:0044238 primary metabolism 17 111 2018 339 7792 2.41E-03
 
 
 
Cluster 17 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.67E-03 2 19 2018 41 7792 3.67E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0009070 serine family amino acid biosynthesis 43 6 2018 9 7792 1.20E-02
GO:0015986 ATP synthesis coupled proton transport 87 13 2018 32 7792 4.87E-02
 
 
 
Cluster 18 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.49E-03 2 4 2018 4 7792 4.49E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006069 ethanol oxidation 23 4 2018 4 7792 4.49E-03
GO:0006067 ethanol metabolism 22 4 2018 4 7792 4.49E-03
 
 
 
Cluster 19 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.90E-03 3 18 2018 39 7792 4.90E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006119 oxidative phosphorylation 27 17 2018 36 7792 4.63E-03
GO:0006754 ATP biosynthesis 85 14 2018 35 7792 4.74E-02
GO:0015985 energy coupled proton transport, down electrochemical gradient 86 13 2018 32 7792 4.87E-02
 
 
 
Cluster 20 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
5.46E-03 2 5 2018 6 7792 5.46E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0009072 aromatic amino acid family metabolism 33 5 2018 6 7792 5.46E-03
GO:0006572 tyrosine catabolism 56 4 2018 5 7792 1.78E-02
 
 
 
Cluster 21 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
9.03E-03 2 17 2018 38 7792 9.03E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006818 hydrogen transport 28 17 2018 36 7792 4.63E-03
GO:0015992 proton transport 37 17 2018 37 7792 6.54E-03
 
 
 
Cluster 22 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.28E-02 4 8 2018 14 7792 1.28E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0006779 porphyrin biosynthesis 42 6 2018 9 7792 1.20E-02
GO:0046148 pigment biosynthesis 62 6 2018 10 7792 2.34E-02
GO:0006783 heme biosynthesis 70 5 2018 8 7792 3.16E-02
GO:0042168 heme metabolism 79 6 2018 11 7792 4.03E-02
 
 
 
Cluster 23 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.56E-02 2 9 2018 17 7792 1.56E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0048278 vesicle docking 31 9 2018 15 7792 5.37E-03
GO:0006904 vesicle docking during exocytosis 72 8 2018 16 7792 3.31E-02
 
 
 
Cluster 24 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.31E-02 2 8 2018 16 7792 3.31E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0051693 actin filament capping 74 8 2018 16 7792 3.31E-02
GO:0051016 barbed-end actin filament capping 73 8 2018 16 7792 3.31E-02
 
 
 
Cluster 25 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.55E-02 2 9 2018 19 7792 3.55E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0007004 telomerase-dependent telomere maintenance 61 6 2018 10 7792 2.34E-02
GO:0000723 telomere maintenance 75 9 2018 19 7792 3.55E-02
 
 
 
Cluster 26 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.03E-02 3 6 2018 11 7792 4.03E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030970 retrograde protein transport, ER to cytosol 53 3 2018 3 7792 1.74E-02
GO:0006984 ER-nuclear signaling pathway 52 3 2018 3 7792 1.74E-02
GO:0043161 proteasomal ubiquitin-dependent protein catabolism 80 6 2018 11 7792 4.03E-02