|
SVF Genes -
KEGG Annotation Clusters |
| |
| Used notations: |
| |
-
"List Hits" - the number of genes annotated by the
considered GO category or annotation cluster within the analyzed list of
target genes
|
- "List Total" - the number of genes
within the analyzed list of target genes having at least one GO annotation
(KEGG)
|
- "Population Hits" - the number of genes, available on
the entire microarray, annotated by the considered GO category or annotation
cluster
|
- "Population Total" - the number of genes available on
the entire microarray and having at least one GO annotation (KEGG)
|
- "P-value" - the significance p-value of the gene
enrichment of the considered GO category or annotation cluster, calculated
with a unilateral Fisher exact test
|
- "FDR (q-value)" - the estimated value of the false
discovery rate (FDR) by using the Benjamini & Hochberg (2001)
method
|
| |
| |
| Cluster 1 |
FDR (q-value) |
Terms |
List Hits |
List Total |
Population Hits |
Population Total |
P-value |
| 1.57E-21 |
7 |
179 |
638 |
416 |
2682 |
1.57E-21 |
| ID |
Term |
Rank |
List Hits |
List Total |
Population Hits |
Population Total |
P-values |
| 4612 |
Antigen processing and
presentation |
1 |
30 |
638 |
46 |
2682 |
2.06E-09 |
| 4940 |
Type I diabetes mellitus |
2 |
25 |
638 |
35 |
2682 |
2.67E-09 |
| 4640 |
Hematopoietic cell lineage |
3 |
37 |
638 |
65 |
2682 |
6.57E-09 |
| 4514 |
Cell adhesion molecules (CAMs) |
4 |
49 |
638 |
101 |
2682 |
2.95E-08 |
| 4060 |
Cytokine-cytokine receptor
interaction |
6 |
65 |
638 |
152 |
2682 |
8.05E-08 |
| 4670 |
Leukocyte transendothelial
migration |
7 |
39 |
638 |
92 |
2682 |
4.66E-05 |
| 4650 |
Natural killer cell mediated
cytotoxicity |
8 |
32 |
638 |
80 |
2682 |
7.84E-04 |
| |
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|
| Cluster 2 |
FDR (q-value) |
Terms |
List Hits |
List Total |
Population Hits |
Population Total |
P-value |
| 2.49E-09 |
5 |
145 |
638 |
406 |
2682 |
2.49E-09 |
| ID |
Term |
Rank |
List Hits |
List Total |
Population Hits |
Population Total |
P-values |
| 4610 |
Complement and coagulation
cascades |
9 |
23 |
638 |
52 |
2682 |
8.47E-04 |
| 4010 |
MAPK signaling pathway |
10 |
58 |
638 |
169 |
2682 |
9.06E-04 |
| 4810 |
Regulation of actin cytoskeleton |
12 |
46 |
638 |
144 |
2682 |
1.36E-02 |
| 4350 |
TGF-beta signaling pathway |
13 |
23 |
638 |
64 |
2682 |
1.83E-02 |
| 532 |
Chondroitin / Heparan sulfate
biosynthesis |
14 |
10 |
638 |
24 |
2682 |
3.95E-02 |
| |
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|
|
| Cluster 3 |
FDR (q-value) |
Terms |
List Hits |
List Total |
Population Hits |
Population Total |
P-value |
| 1.18E-08 |
2 |
57 |
638 |
122 |
2682 |
1.18E-08 |
| ID |
Term |
Rank |
List Hits |
List Total |
Population Hits |
Population Total |
P-values |
| 3010 |
Ribosome |
5 |
34 |
638 |
60 |
2682 |
3.24E-08 |
| 4512 |
ECM-receptor interaction |
11 |
23 |
638 |
62 |
2682 |
1.21E-02 |