Adipocytes Genes - GO Molecular Function Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Molecular Function)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Molecular Function)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
7.21E-14 8 98 2183 193 8424 7.21E-14
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0003954 NADH dehydrogenase activity 2 27 2183 31 8424 1.31E-12
GO:0008137 NADH dehydrogenase (ubiquinone) activity 3 27 2183 32 8424 6.31E-12
GO:0000339 RNA cap binding 6 5 2183 5 8424 1.16E-03
GO:0017111 nucleoside-triphosphatase activity 11 18 2183 39 8424 4.94E-03
GO:0051287 NAD binding 13 9 2183 16 8424 9.53E-03
GO:0046961 hydrogen-transporting ATPase activity, rotational mechanism 34 13 2183 31 8424 3.78E-02
GO:0008034 lipoprotein binding 36 4 2183 6 8424 4.26E-02
GO:0016887 ATPase activity 38 24 2183 67 8424 4.62E-02
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.01E-11 4 170 2183 418 8424 1.01E-11
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005489 electron transporter activity 4 62 2183 138 8424 8.79E-07
GO:0016874 ligase activity 5 62 2183 159 8424 1.80E-04
GO:0005506 iron ion binding 7 56 2183 155 8424 2.94E-03
GO:0005159 insulin-like growth factor receptor binding 32 5 2183 8 8424 3.17E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.94E-11 3 521 2183 1599 8424 1.94E-11
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0016491 oxidoreductase activity 1 144 2183 293 8424 3.43E-18
GO:0005524 ATP binding 26 251 2183 871 8424 2.23E-02
GO:0005554 molecular function unknown 29 138 2183 464 8424 3.12E-02
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.74E-09 9 77 2183 163 8424 2.74E-09
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0009055 electron carrier activity 8 7 2183 10 8424 4.35E-03
GO:0008339 MP kinase activity 18 3 2183 3 8424 1.74E-02
GO:0019787 ubiquitin-like-protein ligase activity 19 3 2183 3 8424 1.74E-02
GO:0008307 structural constituent of muscle 23 11 2183 23 8424 1.93E-02
GO:0019899 enzyme binding 27 10 2183 21 8424 2.62E-02
GO:0003707 steroid hormone receptor activity 28 14 2183 33 8424 2.85E-02
GO:0008121 ubiquinol-cytochrome-c reductase activity 33 5 2183 8 8424 3.17E-02
GO:0003777 microtubule motor activity 35 19 2183 50 8424 4.01E-02
GO:0003950 NAD+ ADP-ribosyltransferase activity 37 7 2183 14 8424 4.58E-02
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
8.87E-09 6 31 2183 47 8424 8.87E-09
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0004459 L-lactate dehydrogenase activity 9 4 2183 4 8424 4.50E-03
GO:0004332 fructose-bisphosphate aldolase activity 15 3 2183 3 8424 1.74E-02
GO:0004300 enoyl-CoA hydratase activity 22 4 2183 5 8424 1.78E-02
GO:0004029 aldehyde dehydrogenase (NAD) activity 21 4 2183 5 8424 1.78E-02
GO:0004722 protein serine/threonine phosphatase activity 25 8 2183 15 8424 2.14E-02
GO:0004601 peroxidase activity 24 8 2183 15 8424 2.14E-02
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.01E-04 2 6 2183 6 8424 3.01E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 20 3 2183 3 8424 1.74E-02
GO:0004886 retinoid-X receptor activity 17 3 2183 3 8424 1.74E-02
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.64E-04 2 10 2183 14 8424 4.64E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0004022 alcohol dehydrogenase activity 12 5 2183 6 8424 5.48E-03
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 30 5 2183 8 8424 3.17E-02
 
 
 
Cluster 8 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.16E-03 2 5 2183 5 8424 1.16E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0009374 biotin binding 10 4 2183 4 8424 4.50E-03
GO:0004075 biotin carboxylase activity 14 3 2183 3 8424 1.74E-02
 
 
 
Cluster 9 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.52E-03 2 8 2183 11 8424 1.52E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0004449 isocitrate dehydrogenase (NAD+) activity 16 3 2183 3 8424 1.74E-02
GO:0005095 GTPase inhibitor activity 31 5 2183 8 8424 3.17E-02