Insulin Up-regulated Genes - KEGG Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered KEGG category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one KEGG annotation
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered KEGG category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one KEGG annotation
  • "P-value" - the significance p-value of the gene enrichment of the considered KEGG category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
6.07E-10 2 41 281 163 3040 6.07E-10
ID Term Rank List Hits List Total Population Hits Population Total P-values
190 Oxidative phosphorylation 2 27 281 98 3040 8.77E-08
3010 Ribosome 6 14 281 65 3040 1.92E-03
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.89E-07 5 38 281 179 3040 3.89E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
3060

Protein export

 4 6 281 11 3040 1.83E-04
4720 Long-term potentiation 8 12 281 61 3040 8.56E-03
4520 Adherens junction 12 12 281 70 3040 2.47E-02
62 Fatty acid elongation in mitochondria 15 3 281 8 3040 3.08E-02
640 Propanoate metabolism 17 7 281 34 3040 3.26E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.03E-05 3 51 281 307 3040 1.03E-05
ID Term Rank List Hits List Total Population Hits Population Total P-values
3050 Proteasome 1 14 281 27 3040 1.62E-08
4810 Regulation of actin cytoskeleton 5 30 281 170 3040 2.88E-04
4510 Focal adhesion 20 25 281 193 3040 4.83E-02
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.35E-05 3 23 281 100 3040 2.35E-05
ID Term Rank List Hits List Total Population Hits Population Total P-values
20 Citrate cycle (TCA cycle) 3 8 281 19 3040 1.47E-04
10 Glycolysis / Gluconeogenesis 14 9 281 48 3040 2.89E-02
193 ATP synthesis 16 7 281 34 3040 3.26E-02
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.31E-02 3 13 281 72 3040 1.31E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
4612 Antigen processing and presentation 9 10 281 50 3040 1.41E-02
4940 Type I diabetes mellitus 10 8 281 38 3040 2.02E-02
362 Benzoate degradation via hydroxylation 11 2 281 3 3040 2.40E-02
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.73E-02 2 8 281 37 3040 1.73E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
710 Carbon fixation 13 5 281 19 3040 2.56E-02
252 Alanine and aspartate metabolism 19 5 281 22 3040 4.62E-02
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.51E-02 2 2 281 4 3040 4.51E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
401 Novobiocin biosynthesis 7 2 281 2 3040 8.52E-03
950 Alkaloid biosynthesis I 18 2 281 4 3040 4.51E-02