Insulin Down-regulated Genes - GO Cellular Component Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Cellular Component)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Cellular Component)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
5.30E-04 3 3 115 12 8247 5.30E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0008091 spectrin 2 2 115 8 8247 5.11E-03
GO:0030864 cortical actin cytoskeleton 3 2 115 10 8247 8.06E-03
GO:0008385 IkappaB kinase complex 10 1 115 2 8247 2.77E-02
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.35E-03 3 3 115 22 8247 3.35E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0000940 outer kinetochore of condensed chromosome 8 1 115 2 8247 2.77E-02
GO:0000777 condensed chromosome kinetochore 7 1 115 2 8247 2.77E-02
GO:0019717 synaptosome 12 2 115 20 8247 3.11E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.39E-02 1 1 115 1 8247 1.39E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0009348 ornithine carbamoyltransferase complex 4 1 115 1 8247 1.39E-02
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.76E-02 4 15 115 594 8247 1.76E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005819 spindle 1 3 115 25 8247 4.86E-03
GO:0015630 microtubule cytoskeleton 6 6 115 163 8247 2.62E-02
GO:0005874 microtubule 13 5 115 130 8247 3.50E-02
GO:0043232 intracellular non-membrane-bound organelle 14 12 115 488 8247 3.89E-02
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.77E-02 2 1 115 2 8247 2.77E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0043226 organelle 5 1 115 1 8247 1.39E-02
GO:0043229 intracellular organelle 11 1 115 2 8247 2.77E-02
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.77E-02 1 1 115 2 8247 2.77E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005958 DNA-dependent protein kinase complex 9 1 115 2 8247 2.77E-02
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.13E-02 1 1 115 3 8247 4.13E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005594 collagen type IX 15 1 115 3 8247 4.13E-02