Insulin Up-regulated Genes - GO Cellular Component Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Cellular Component)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Cellular Component)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
6.27E-16 2 160 645 1115 8247 6.27E-16
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005739 mitochondrion 2 81 645 476 8247 6.91E-12
GO:0043234 protein complex 8 85 645 694 8247 1.33E-05
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
5.94E-11 5 27 645 83 8247 5.94E-11
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0000502

proteasome complex (sensu Eukaryota)

 4 15 645 37 8247 3.94E-08
GO:0005839 proteasome core complex (sensu Eukaryota) 6 10 645 18 8247 1.97E-07
GO:0030530 heterogeneous nuclear ribonucleoprotein complex 13 6 645 15 8247 6.06E-04
GO:0005838 proteasome regulatory particle (sensu Eukaryota) 27 3 645 7 8247 1.31E-02
GO:0016469 proton-transporting two-sector ATPase complex 40 6 645 31 8247 3.05E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
9.71E-11 2 402 645 4146 8247 9.71E-11
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005737 cytoplasm 1 254 645 1959 8247 2.21E-20
GO:0043231 intracellular membrane-bound organelle 10 306 645 3335 8247 1.04E-04
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
8.71E-09 3 86 645 596 8247 8.71E-09
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005829 cytosol 3 43 645 228 8247 3.90E-08
GO:0015629 actin cytoskeleton 16 22 645 143 8247 1.59E-03
GO:0005856 cytoskeleton 25 38 645 328 8247 8.89E-03
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
7.11E-07 4 23 645 95 8247 7.11E-07
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005743 mitochondrial inner membrane 7 18 645 70 8247 4.59E-06
GO:0031966 mitochondrial membrane 12 13 645 59 8247 5.08E-04
GO:0005746 mitochondrial electron transport chain 14 6 645 16 8247 9.06E-04
GO:0019866 organelle inner membrane 15 10 645 43 8247 1.43E-03
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.38E-06 4 84 645 646 8247 1.38E-06
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030529 ribonucleoprotein complex 5 44 645 246 8247 1.35E-07
GO:0005840 ribosome 9 22 645 110 8247 3.33E-05
GO:0043232 intracellular non-membrane-bound organelle 11 59 645 488 8247 4.29E-04
GO:0005884 actin filament 17 5 645 14 8247 3.18E-03
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.28E-06 6 21 645 87 8247 2.28E-06
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0015934 large ribosomal subunit 20 6 645 21 8247 4.38E-03
GO:0005830 cytosolic ribosome (sensu Eukaryota) 22 7 645 30 8247 7.19E-03
GO:0016282 eukaryotic 43S preinitiation complex 24 6 645 24 8247 8.89E-03
GO:0005842 cytosolic large ribosomal subunit (sensu Eukaryota) 26 5 645 18 8247 1.05E-02
GO:0005761 mitochondrial ribosome 47 5 645 24 8247 3.52E-02
GO:0005740 mitochondrial envelope 49 4 645 17 8247 3.89E-02
 
 
 
Cluster 8 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
5.21E-04 3 5 645 10 8247 5.21E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0043034 costamere 21 2 645 2 8247 6.11E-03
GO:0016272 prefoldin complex 23 3 645 6 8247 7.96E-03
GO:0030016 myofibril 41 2 645 4 8247 3.29E-02
 
 
 
Cluster 9 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.40E-03 2 4 645 9 8247 3.40E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0048500 signal recognition particle 19 4 645 9 8247 3.40E-03
GO:0005786 signal recognition particle (sensu Eukaryota) 18 4 645 9 8247 3.40E-03
 
 
 
Cluster 10 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.44E-03 3 13 645 74 8247 4.44E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0042579 microbody 30 9 645 50 8247 1.43E-02
GO:0045259 proton-transporting ATP synthase complex 34 4 645 14 8247 1.97E-02
GO:0005777 peroxisome 52 9 645 60 8247 4.22E-02
 
 
 
Cluster 11 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
5.24E-03 3 12 645 67 8247 5.24E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0008305 integrin complex 31 7 645 34 8247 1.45E-02
GO:0005852 eukaryotic translation initiation factor 3 complex 35 3 645 8 8247 1.98E-02
GO:0043235 receptor complex 48 9 645 59 8247 3.84E-02
 
 
 
Cluster 12 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.31E-02 2 3 645 7 8247 1.31E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0016529 sarcoplasmic reticulum 29 3 645 7 8247 1.31E-02
GO:0016528 sarcoplasm 28 3 645 7 8247 1.31E-02
 
 
 
Cluster 13 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.80E-02 2 3 645 9 8247 2.80E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0045255 hydrogen-translocating F-type ATPase complex 39 3 645 9 8247 2.80E-02
GO:0005753 proton-transporting ATP synthase complex (sensu Eukaryota) 38 3 645 9 8247 2.80E-02
 
 
 
Cluster 14 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.05E-02 3 6 645 31 8247 3.05E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030120 vesicle coat 37 6 645 30 8247 2.63E-02
GO:0030118 clathrin coat 50 4 645 17 8247 3.89E-02
GO:0030665 clathrin coated vesicle membrane 53 4 645 18 8247 4.70E-02
 
 
 
Cluster 15 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.29E-02 3 2 645 4 8247 3.29E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005750 respiratory chain complex III (sensu Eukaryota) 32 2 645 3 8247 1.74E-02
GO:0045275 respiratory chain complex III 45 2 645 4 8247 3.29E-02
GO:0045285 ubiquinol-cytochrome-c reductase complex 46 2 645 4 8247 3.29E-02
 
 
 
Cluster 16 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.29E-02 2 2 645 4 8247 3.29E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030119 membrane coat adaptor complex 44 2 645 4 8247 3.29E-02
GO:0030117 membrane coat 43 2 645 4 8247 3.29E-02
 
 
 
Cluster 17 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.77E-02 2 3 645 10 8247 3.77E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005912 adherens junction 36 3 645 8 8247 1.98E-02
GO:0030055 cell-matrix junction 42 2 645 4 8247 3.29E-02
 
 
 
Cluster 18 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
4.13E-02 2 5 645 25 8247 4.13E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0000159 protein phosphatase type 2A complex 33 4 645 14 8247 1.97E-02
GO:0008287 protein serine/threonine phosphatase complex 51 5 645 25 8247 4.13E-02