Insulin Up-regulated Genes - GO Cellular Component Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Cellular Component)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Cellular Component)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.93E-17 7 66 645 276 8247 3.93E-17
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005839 proteasome core complex (sensu Eukaryota) 2 10 645 18 8247 1.97E-07
GO:0005840 ribosome 4 21 645 98 8247 1.68E-05
GO:0005743 mitochondrial inner membrane 6 10 645 40 8247 7.84E-04
GO:0005884 actin filament 7 5 645 13 8247 2.18E-03
GO:0043234 protein complex 9 8 645 35 8247 4.74E-03
GO:0005777 peroxisome 17 9 645 50 8247 1.43E-02
GO:0016469 proton-transporting two-sector ATPase complex 27 6 645 31 8247 3.05E-02
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.99E-15 3 188 645 1422 8247 3.99E-15
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005739 mitochondrion 1 78 645 465 8247 3.71E-11
GO:0005829 cytosol 3 35 645 188 8247 1.01E-06
GO:0005737 cytoplasm 12 79 645 786 8247 1.04E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.99E-12 10 35 645 120 8247 2.99E-12
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005786 signal recognition particle (sensu Eukaryota) 8 4 645 9 8247 3.40E-03
GO:0005842 cytosolic large ribosomal subunit (sensu Eukaryota) 13 5 645 18 8247 1.05E-02
GO:0005746 mitochondrial electron transport chain 14 4 645 12 8247 1.10E-02
GO:0016529 sarcoplasmic reticulum 16 3 645 7 8247 1.31E-02
GO:0008305 integrin complex 18 7 645 34 8247 1.45E-02
GO:0005750 respiratory chain complex III (sensu Eukaryota) 22 2 645 3 8247 1.74E-02
GO:0005753 proton-transporting ATP synthase complex (sensu Eukaryota) 26 3 645 9 8247 2.80E-02
GO:0030119 membrane coat adaptor complex 29 2 645 4 8247 3.29E-02
GO:0030125 clathrin vesicle coat 32 4 645 17 8247 3.89E-02
GO:0005740 mitochondrial envelope 33 3 645 11 8247 4.89E-02
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
5.24E-06 4 17 645 64 8247 5.24E-06
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005838 proteasome regulatory particle (sensu Eukaryota) 15 3 645 7 8247 1.31E-02
GO:0005768 endosome 19 7 645 35 8247 1.69E-02
GO:0000159 protein phosphatase type 2A complex 24 4 645 14 8247 1.97E-02
GO:0005852 eukaryotic translation initiation factor 3 complex 25 3 645 8 8247 1.98E-02
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
9.69E-06 3 7 645 12 8247 9.69E-06
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0043034 costamere 10 2 645 2 8247 6.11E-03
GO:0016272 prefoldin complex 11 3 645 6 8247 7.96E-03
GO:0031965 nuclear membrane 30 2 645 4 8247 3.29E-02
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.21E-04 2 17 645 84 8247 2.21E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030530 heterogeneous nuclear ribonucleoprotein complex 5 6 645 15 8247 6.06E-04
GO:0015629 actin cytoskeleton 20 11 645 69 8247 1.73E-02
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.10E-02 2 4 645 12 8247 1.10E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0000793 condensed chromosome 21 2 645 3 8247 1.74E-02
GO:0000228 nuclear chromosome 31 3 645 10 8247 3.77E-02
 
 
 
Cluster 8 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.74E-02 1 2 645 3 8247 1.74E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0016599

caveolar membrane

 23 2 645 3 8247 1.74E-02
 
 
 
Cluster 9 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.29E-02 1 2 645 4 8247 3.29E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005912 adherens junction 28 2 645 4 8247 3.29E-02