Insulin Up-regulated Genes - GO Cellular Component Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered GO category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one GO annotation (Cellular Component)
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered GO category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one GO annotation (Cellular Component)
  • "P-value" - the significance p-value of the gene enrichment of the considered GO category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
6.51E-12 2 180 496 1468 6440 5.92E-13
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005737 cytoplasm 1 175 496 1442 6440 5.99E-12
GO:0005739 mitochondrion 2 64 496 362 6440 9.82E-11
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.05E-09 7 42 496 196 6440 5.55E-10
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030529 ribonucleoprotein complex 3 30 496 151 6440 9.92E-07
GO:0005840 ribosome 6 17 496 75 6440 3.99E-05
GO:0005830 cytosolic ribosome (sensu Eukarya) 10 6 496 23 6440 6.59E-03
GO:0016282 eukaryotic 43S preinitiation complex 11 6 496 23 6440 6.59E-03
GO:0005884 actin filament 12 4 496 11 6440 7.41E-03
GO:0030530 heterogeneous nuclear ribonucleoprotein complex 13 4 496 11 6440 7.41E-03
GO:0000119 mediator complex 36 3 496 11 6440 4.70E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.13E-07 3 15 496 37 6440 3.09E-08
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0000502 proteasome complex (sensu Eukarya) 4 11 496 30 6440 7.18E-06
GO:0005839 proteasome core complex (sensu Eukarya) 7 7 496 15 6440 5.75E-05
GO:0005786 signal recognition particle 8 4 496 7 6440 1.01E-03
 
 
 
Cluster 4 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.62E-07 5 66 496 441 6440 5.90E-08
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0005829 cytosol 5 26 496 141 6440 2.15E-05
GO:0005743 mitochondrial inner membrane 9 12 496 60 6440 1.75E-03
GO:0005868 cytoplasmic dynein complex 14 3 496 6 6440 7.61E-03
GO:0005768 endosome 19 7 496 35 6440 1.56E-02
GO:0005856 cytoskeleton 34 24 496 214 6440 3.89E-02
 
 
 
Cluster 5 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.89E-04 4 17 496 82 6440 1.31E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0008305 integrin complex 15 7 496 31 6440 7.96E-03
GO:0042579 microbody 23 7 496 37 6440 2.09E-02
GO:0005777 peroxisome 31 7 496 41 6440 3.51E-02
GO:0005744 mitochondrial inner membrane presequence translocase complex 32 3 496 10 6440 3.62E-02
 
 
 
Cluster 6 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.74E-04 5 12 496 48 6440 2.04E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0030120 vesicle coat 17 5 496 19 6440 1.25E-02
GO:0030118 clathrin coat 24 4 496 15 6440 2.40E-02
GO:0005746 mitochondrial electron transport chain 25 3 496 9 6440 2.69E-02
GO:0000151 ubiquitin ligase complex 33 4 496 17 6440 3.70E-02
GO:0030125 clathrin vesicle coat 35 4 496 18 6440 4.47E-02
 
 
 
Cluster 7 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.64E-02 2 4 496 12 6440 1.04E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0015934 large ribosomal subunit 16 4 496 12 6440 1.04E-02
GO:0005842 cytosolic large ribosomal subunit (sensu Eukarya) 37 3 496 11 6440 4.70E-02
 
 
 
Cluster 8 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.73E-02 2 3 496 7 6440 1.26E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0016010 dystrophin-associated glycoprotein complex 28 2 496 4 6440 3.20E-02
GO:0005901 caveola 26 2 496 4 6440 3.20E-02
 
 
 
Cluster 9 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.32E-02 3 3 496 8 6440 1.90E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0045255 hydrogen-translocating F-type ATPase complex 21 3 496 8 6440 1.90E-02
GO:0005753 proton-transporting ATP synthase complex (sensu Eukarya) 20 3 496 8 6440 1.90E-02
GO:0045259 proton-transporting ATP synthase complex 22 3 496 8 6440 1.90E-02
 
 
 
Cluster 10 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.32E-02 2 2 496 4 6440 3.20E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0045285 ubiquinol-cytochrome-c reductase complex 29 2 496 4 6440 3.20E-02
GO:0015008 ubiquinol-cytochrome-c reductase complex (sensu Eukarya) 27 2 496 4 6440 3.20E-02
 
 
 
Cluster 11 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
3.32E-02 2 5 496 24 6440 3.32E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
GO:0000159 protein phosphatase type 2A complex 18 4 496 13 6440 1.42E-02
GO:0008287 protein serine/threonine phosphatase complex 30 5 496 24 6440 3.32E-02