Insulin Down-regulated Genes - KEGG Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered KEGG category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one KEGG annotation
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered KEGG category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one KEGG annotation
  • "P-value" - the significance p-value of the gene enrichment of the considered KEGG category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
9.68E-02 1 2 20 31 1729 4.84E-02
ID Term Rank List Hits List Total Population Hits Population Total P-values
120 Bile acid biosynthesis 6 2 20 31 1729 4.84E-02
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
2.01E-01 5 4 20 203 1729 2.01E-01
ID Term Rank List Hits List Total Population Hits Population Total P-values
632 Benzoate degradation via CoA ligation 1 4 20 96 1729 2.18E-02
600 Sphingoglycolipid metabolism 2 4 20 101 1729 2.58E-02
760 Nicotinate and nicotinamide metabolism 3 4 20 102 1729 2.66E-02
562 Inositol phosphate metabolism 4 4 20 104 1729 2.84E-02
500 Starch and sucrose metabolism 5 4 20 110 1729 3.40E-02