Insulin Up-regulated Genes - KEGG Annotation Clusters
 
Used notations:
 
  • "List Hits" - the number of genes annotated by the considered KEGG category or annotation cluster within the analyzed list of target genes
  • "List Total" - the number of genes within the analyzed list of target genes having at least one KEGG annotation
  • "Population Hits" - the number of genes, available on the entire microarray, annotated by the considered KEGG category or annotation cluster
  • "Population Total" - the number of genes available on the entire microarray and having at least one KEGG annotation
  • "P-value" - the significance p-value of the gene enrichment of the considered KEGG category or annotation cluster, calculated with a unilateral Fisher exact test
  • "FDR (q-value)" - the estimated value of the false discovery rate (FDR) by using the Benjamini & Hochberg (2001) method
 
 
Cluster 1 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
1.52E-13 6 61 190 180 1729 5.06E-14
ID Term Rank List Hits List Total Population Hits Population Total P-values
3050 Proteasome 1 14 190 27 1729 1.31E-07
190 Oxidative phosphorylation 2 27 190 95 1729 1.07E-06
20 Citrate cycle (TCA cycle) 3 8 190 19 1729 4.77E-04
3060 Protein export 4 5 190 10 1729 2.42E-03
272 Cysteine metabolism 9 4 190 13 1729 4.56E-02
30 Pentose phosphate pathway 10 5 190 19 1729 4.90E-02
 
 
 
Cluster 2 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
6.99E-04 2 19 190 78 1729 4.66E-04
ID Term Rank List Hits List Total Population Hits Population Total P-values
3010 Ribosome 5 14 190 61 1729 4.82E-03
710 Carbon fixation 6 5 190 17 1729 3.12E-02
 
 
 
Cluster 3 FDR (q-value) Terms List Hits List Total Population Hits Population Total P-value
7.11E-03 2 9 190 33 1729 7.11E-03
ID Term Rank List Hits List Total Population Hits Population Total P-values
362 Benzoate degradation via hydroxylation 7 2 190 3 1729 3.34E-02
640 Propanoate metabolism 8 7 190 30 1729 3.91E-02