Genes DOWN -
KEGG Annotations
Used notations:
List Hits - the number of genes
annotated by the considered KEGG category or annotation cluster within
the analyzed list of target genes
List Total
- the number of genes within the analyzed list of target genes
having at least one KEGG annotation
Population Hits
- the number of genes, available on the entire microarray, annotated
by the considered KEGG category or annotation cluster
Population Total - the number of genes available on the
entire microarray and having at least one KEGG annotation
P-value - the significance p-value of
the gene enrichment of the considered KEGG category or annotation
cluster, calculated with a unilateral Fisher exact test
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Rank
ID
Term
List
Hits
List
Total
Population
Hits
Population
Total
P-value
Genes ID's
Genes Names
1
00350
Tyrosine metabolism
9
295
22
1328
3.69e-02
alcohol dehydrogenase IB (class I), beta polypeptide alcohol dehydrogenase 5 (class III), chi polypeptide glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) aldehyde oxidase 1 4-hydroxyphenylpyruvate dioxygenase monoamine oxidase A SH3-domain GRB2-like endophilin B1 ARD1 homolog A, N-acetyltransferase (S. cerevisiae) amine oxidase, copper containing 3 (vascular adhesion protein 1)
2
04070
Phosphatidylinositol signaling system
9
295
23
1328
4.91e-02
diacylglycerol kinase, eta inositol polyphosphate-1-phosphatase phosphoinositide-3-kinase, class 2, beta polypeptide phosphoinositide-3-kinase, catalytic, gamma polypeptide phosphatidylinositol 4-kinase, catalytic, beta polypeptide phosphatidylinositol-4-phosphate 5-kinase, type II, alpha phospholipase C, beta 3 (phosphatidylinositol-specific) inositol polyphosphate-5-phosphatase, 72 kDa calmodulin 3 (phosphorylase kinase, delta)
3
00360
Phenylalanine metabolism
6
295
12
1328
3.12e-02
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 4-hydroxyphenylpyruvate dioxygenase monoamine oxidase A SH3-domain GRB2-like endophilin B1 ARD1 homolog A, N-acetyltransferase (S. cerevisiae) amine oxidase, copper containing 3 (vascular adhesion protein 1)
4
00960
Alkaloid biosynthesis II
4
295
7
1328
4.72e-02
lipase A, lysosomal acid, cholesterol esterase (Wolman disease) SH3-domain GRB2-like endophilin B1 ARD1 homolog A, N-acetyltransferase (S. cerevisiae) amine oxidase, copper containing 3 (vascular adhesion protein 1)
5
05060
Prion disease
4
295
6
1328
2.45e-02
heat shock 60kDa protein 1 (chaperonin) laminin, gamma 1 (formerly LAMB2) nuclear factor (erythroid-derived 2)-like 2 prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
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