ECM related genes — summary of the three analyzed conditions
ECM component |
Gene ID |
Symbol |
Name |
Obese/lean |
After/before bypass |
AcMC |
Tissular fraction |
ECM role |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|
Fold |
q-value (%) |
Fold |
q-value (%) |
Fold |
q-value (%) |
||||||
Structural proteins |
|||||||||||
COL12A1 |
collagen, type XII, alpha 1 | 2.24 |
1.54 |
— |
— |
0.67 |
0.70 |
— |
proper matrix |
||
COL5A2 |
collagen, type V, alpha 2 | 1.79 |
1.67 |
— |
— |
1.64 |
0.26 |
SVF |
proper matrix |
||
COL4A1 |
collagen, type IV, alpha 1 | 1.77 |
0.39 |
0.75 |
1.93 |
0.61 |
0.37 |
SVF |
proper matrix |
||
COL1A1 |
collagen, type I, alpha 1 | 0.64 |
4.72 |
7.18 |
1.46 |
0.89 |
4.77 |
SVF |
proper matrix |
||
COL1A2 |
collagen, type I, alpha 2 | — |
— |
6.64 |
1.93 |
3.47 |
0.00 |
SVF |
proper matrix |
||
ELN |
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | — |
— |
3.64 |
2.96 |
0.26 |
0.00 |
SVF |
proper matrix |
||
COL6A3 |
collagen, type VI, alpha 3 | — |
— |
3.28 |
2.96 |
1.23 |
3.94 |
— |
proper matrix |
||
EMILIN2 |
elastin microfibril interfacer 2 | — |
— |
2.60 |
1.06 |
1.45 |
3.94 |
SVF |
proper matrix |
||
COL6A2 |
collagen, type VI, alpha 2 | — |
— |
2.24 |
0.19 |
3.68 |
0.00 |
SVF |
cell matrix adhesion |
||
COL6A1 |
collagen, type VI, alpha 1 | — |
— |
1.93 |
2.96 |
1.86 |
0.50 |
SVF |
cell matrix adhesion |
||
EMILIN1 |
elastin microfibril interfacer 1 | — |
— |
1.38 |
1.93 |
— |
— |
SVF |
proper matrix |
||
COL14A1 |
collagen, type XIV, alpha 1 (undulin) | — |
— |
1.36 |
2.96 |
— |
— |
— |
cell matrix adhesion |
||
COL5A3 |
collagen, type V, alpha 3 | — |
— |
1.28 |
0.48 |
— |
— |
Adipocyte |
proper matrix |
||
COL11A2 |
collagen, type XI, alpha 2 | — |
— |
0.78 |
3.61 |
— |
— |
SVF |
proper matrix |
||
COL15A1 |
collagen, type XV, alpha 1 | — |
— |
0.77 |
3.61 |
0.43 |
0.00 |
SVF |
proper matrix |
||
COL2A1 |
collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | — |
— |
0.76 |
2.59 |
— |
— |
— |
proper matrix |
||
COL24A1 |
collagen, type XXIV, alpha 1 | — |
— |
0.72 |
1.06 |
— |
— |
SVF |
proper matrix |
||
COL21A1 |
collagen, type XXI, alpha 1 | — |
— |
0.72 |
0.00 |
0.84 |
4.49 |
SVF |
proper matrix |
||
Glycoproteins |
|||||||||||
ITGAV |
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 2.01 |
2.44 |
0.72 |
1.06 |
1.25 |
3.24 |
Adipocyte |
cell matrix adhesion |
||
ITGB1 |
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 1.96 |
0.82 |
— |
— |
— |
— |
Adipocyte |
cell matrix adhesion |
||
CLEC4A |
C-type lectin domain family 4, member A | 1.81 |
3.07 |
— |
— |
— |
— |
SVF |
cell cell adhesion |
||
ITGAM |
integrin, alpha M (complement component 3 receptor 3 subunit) | 1.61 |
1.00 |
— |
— |
2.85 |
0.00 |
SVF |
cell matrix adhesion |
||
ITGB2 |
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 1.52 |
3.65 |
— |
— |
1.19 |
3.94 |
SVF |
cell matrix adhesion |
||
ITGB5 |
integrin, beta 5 | 1.48 |
3.65 |
— |
— |
— |
— |
— |
cell matrix adhesion |
||
LAMB1 |
laminin, beta 1 | 1.46 |
4.72 |
— |
— |
1.59 |
0.37 |
— |
cell matrix adhesion |
||
CNTNAP1 |
contactin associated protein 1 | 1.26 |
4.72 |
— |
— |
0.32 |
0.00 |
SVF |
cell matrix adhesion |
||
TNXB |
tenascin XB | 0.78 |
1.54 |
2.46 |
0.48 |
— |
— |
SVF |
cell matrix adhesion |
||
LGALS3BP |
lectin, galactoside-binding, soluble, 3 binding protein | 0.68 |
2.44 |
2.26 |
0.73 |
8.00 |
0.00 |
Adipocyte |
cell cell adhesion |
||
LGALS1 |
lectin, galactoside-binding, soluble, 1 (galectin 1) | 0.64 |
2.44 |
— |
— |
3.95 |
0.00 |
— |
cell matrix adhesion |
||
AZGP1 |
alpha-2-glycoprotein 1, zinc | 0.53 |
0.00 |
— |
— |
— |
— |
Adipocyte |
cell matrix adhesion |
||
SIGLEC1 |
sialic acid binding Ig-like lectin 1, sialoadhesin | — |
— |
4.13 |
0.33 |
— |
— |
SVF |
cell cell adhesion |
||
THBS2 |
thrombospondin 2 | — |
— |
3.49 |
0.66 |
2.54 |
1.25 |
SVF |
cell matrix adhesion |
||
POSTN |
periostin, osteoblast specific factor | — |
— |
2.14 |
4.32 |
0.34 |
0.00 |
SVF |
cell matrix adhesion |
||
CLEC3B |
C-type lectin domain family 3, member B | — |
— |
2.06 |
2.96 |
0.38 |
0.00 |
SVF |
cell cell adhesion |
||
LAMB2 |
laminin, beta 2 (laminin S) | — |
— |
2.00 |
0.00 |
3.31 |
0.00 |
— |
cell matrix adhesion |
||
THBS3 |
thrombospondin 3 | — |
— |
2.00 |
1.93 |
0.40 |
0.00 |
SVF |
cell matrix adhesion |
||
OLR1 |
oxidised low density lipoprotein (lectin-like) receptor 1 | — |
— |
1.46 |
1.93 |
— |
— |
— |
cell cell adhesion |
||
CDH7 |
cadherin 7, type 2 | — |
— |
1.41 |
1.46 |
— |
— |
— |
cell cell adhesion |
||
LMAN2L |
lectin, mannose-binding 2-like | — |
— |
1.36 |
1.46 |
1.73 |
0.11 |
SVF |
cell cell adhesion |
||
LAMA5 |
laminin, alpha 5 | — |
— |
1.34 |
0.33 |
— |
— |
SVF |
cell matrix adhesion |
||
ITGBL1 |
integrin, beta-like 1 (with EGF-like repeat domains) | — |
— |
1.25 |
3.61 |
1.53 |
0.26 |
— |
cell matrix adhesion |
||
RECK |
reversion-inducing-cysteine-rich protein with kazal motifs | — |
— |
1.19 |
1.69 |
3.42 |
0.02 |
— |
remodeling |
||
SIGLEC6 |
sialic acid binding Ig-like lectin 6 | — |
— |
0.90 |
2.23 |
2.49 |
0.00 |
— |
cell cell adhesion |
||
MAG |
myelin associated glycoprotein | — |
— |
0.89 |
3.61 |
— |
— |
— |
cell matrix adhesion |
||
CDH26 |
cadherin-like 26 | — |
— |
0.85 |
4.32 |
— |
— |
SVF |
cell cell adhesion |
||
NTN1 |
netrin 1 | — |
— |
0.79 |
4.32 |
— |
— |
— |
cell matrix adhesion |
||
CDH18 |
cadherin 18, type 2 | — |
— |
0.80 |
1.46 |
— |
— |
— |
cell cell adhesion |
||
PCDH19 |
protocadherin 19 | — |
— |
0.78 |
4.32 |
— |
— |
SVF |
cell cell adhesion |
||
LAMA3 |
laminin, alpha 3 | — |
— |
0.77 |
3.61 |
1.21 |
3.94 |
Adipocyte |
cell matrix adhesion |
||
LAMA4 |
laminin, alpha 4 | — |
— |
0.76 |
2.59 |
1.05 |
3.94 |
SVF |
cell matrix adhesion |
||
LAMA2 |
laminin, alpha 2 (merosin, congenital muscular dystrophy) | — |
— |
0.73 |
0.48 |
1.06 |
3.94 |
SVF |
cell matrix adhesion |
||
TREH |
trehalase (brush-border membrane glycoprotein) | — |
— |
0.72 |
0.45 |
— |
— |
SVF |
remodeling |
||
THBS1 |
thrombospondin 1 | — |
— |
0.72 |
1.06 |
— |
— |
Adipocyte |
cell matrix adhesion |
||
ITGB4 |
integrin, beta 4 | — |
— |
0.72 |
1.20 |
— |
— |
— |
cell matrix adhesion |
||
LGALS8 |
lectin, galactoside-binding, soluble, 8 (galectin 8) | — |
— |
0.70 |
1.06 |
2.42 |
0.00 |
SVF |
cell cell adhesion |
||
CDH13 |
cadherin 13, H-cadherin (heart) | — |
— |
0.70 |
0.48 |
1.95 |
0.70 |
SVF |
cell cell adhesion |
||
CDH17 |
cadherin 17, LI cadherin (liver-intestine) | — |
— |
0.66 |
1.46 |
— |
— |
SVF |
cell cell adhesion |
||
OMG |
oligodendrocyte myelin glycoprotein | — |
— |
0.66 |
0.00 |
— |
— |
— |
cell matrix adhesion |
||
MUCDHL |
mucin and cadherin-like | — |
— |
0.63 |
0.33 |
— |
— |
— |
cell cell adhesion |
||
ITGB6 |
integrin, beta 6 | — |
— |
0.60 |
1.46 |
— |
— |
SVF |
cell matrix adhesion |
||
NID2 |
nidogen 2 (osteonidogen) | — |
— |
0.60 |
1.06 |
1.51 |
3.94 |
SVF |
cell matrix adhesion |
||
GP9 |
glycoprotein IX (platelet) | — |
— |
0.53 |
1.46 |
— |
— |
SVF |
cell matrix adhesion |
||
LGALS4 |
lectin, galactoside-binding, soluble, 4 (galectin 4) | — |
— |
0.50 |
0.33 |
— |
— |
SVF |
cell cell adhesion |
||
CELSR2 |
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | — |
— |
0.50 |
0.00 |
— |
— |
SVF |
cell matrix adhesion |
||
SELL |
selectin L (lymphocyte adhesion molecule 1) | — |
— |
0.31 |
0.00 |
— |
— |
SVF |
cell cell adhesion |
||
SELE |
selectin E (endothelial adhesion molecule 1) | — |
— |
0.28 |
0.00 |
— |
— |
SVF |
cell cell adhesion |
||
ITGA5 |
integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | — |
— |
— |
— |
7.18 |
0.00 |
— |
cell matrix adhesion |
||
LMAN1 |
lectin, mannose-binding, 1 | — |
— |
— |
— |
3.10 |
0.00 |
— |
cell cell adhesion |
||
FN1 |
fibronectin 1 | — |
— |
— |
— |
2.28 |
0.03 |
SVF |
cell matrix adhesion |
||
CD44 |
CD44 molecule (Indian blood group) | — |
— |
— |
— |
1.44 |
0.37 |
SVF |
cell matrix adhesion |
||
Glycosaminoglycans and proteoglycans |
|||||||||||
SDCBP |
syndecan binding protein (syntenin) | 2.48 |
0.28 |
— |
— |
0.55 |
0.01 |
— |
cell cell adhesion |
||
LUM |
lumican | 1.67 |
2.44 |
— |
— |
2.86 |
0.00 |
SVF |
proper matrix |
||
PIGT |
phosphatidylinositol glycan anchor biosynthesis, class T | — |
— |
2.00 |
0.73 |
2.41 |
0.03 |
— |
remodeling |
||
DAG1 |
dystroglycan 1 (dystrophin-associated glycoprotein 1) | — |
— |
1.93 |
2.23 |
0.66 |
0.92 |
SVF |
cell matrix adhesion |
||
HAPLN3 |
hyaluronan and proteoglycan link protein 3 | — |
— |
1.87 |
1.06 |
2.81 |
0.00 |
— |
cell matrix adhesion |
||
SDC3 |
syndecan 3 (N-syndecan) | — |
— |
1.59 |
0.33 |
0.76 |
3.24 |
SVF |
cell matrix adhesion |
||
PIGM |
phosphatidylinositol glycan anchor biosynthesis, class M | — |
— |
1.55 |
1.93 |
— |
— |
— |
remodeling |
||
SDC2 |
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | — |
— |
1.32 |
2.23 |
1.41 |
2.11 |
— |
cell matrix adhesion |
||
SPOCK1 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | — |
— |
1.15 |
3.61 |
0.60 |
0.37 |
SVF |
proper matrix |
||
GPC3 |
glypican 3 | — |
— |
0.92 |
2.96 |
0.64 |
0.26 |
SVF |
cell matrix adhesion |
||
PIGL |
phosphatidylinositol glycan anchor biosynthesis, class L | — |
— |
0.91 |
3.61 |
— |
— |
— |
remodeling |
||
SPARCL1 |
SPARC-like 1 (mast9, hevin) | — |
— |
0.88 |
2.59 |
— |
— |
SVF |
proper matrix |
||
PIGK |
phosphatidylinositol glycan anchor biosynthesis, class K | — |
— |
0.85 |
1.93 |
1.33 |
0.70 |
— |
remodeling |
||
PODN |
podocan | — |
— |
0.68 |
0.00 |
— |
— |
— |
proper matrix |
||
PIGF |
phosphatidylinositol glycan anchor biosynthesis, class F | — |
— |
0.67 |
0.45 |
0.63 |
0.01 |
— |
remodeling |
||
SDC1 |
syndecan 1 | — |
— |
0.63 |
0.00 |
— |
— |
SVF |
cell matrix adhesion |
||
DMP1 |
dentin matrix acidic phosphoprotein | — |
— |
— |
— |
1.97 |
0.00 |
— |
cell matrix adhesion |
||
SGCB |
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | — |
— |
— |
— |
1.90 |
0.00 |
Adipocyte |
cell matrix adhesion |
||
Enzymes |
|||||||||||
TFPI2 |
tissue factor pathway inhibitor 2 | 1.74 |
0.00 |
— |
— |
7.06 |
0.00 |
SVF |
remodeling |
||
RPN1 |
ribophorin I | 1.61 |
0.00 |
1.18 |
2.59 |
1.88 |
0.00 |
— |
remodeling |
||
ADAM12 |
ADAM metallopeptidase domain 12 (meltrin alpha) | 1.61 |
0.00 |
— |
— |
1.14 |
3.94 |
Adipocyte |
remodeling |
||
LOX |
lysyl oxidase | 1.53 |
3.07 |
— |
— |
— |
— |
SVF |
remodeling |
||
CTSS |
cathepsin S | 1.49 |
3.07 |
— |
— |
1.80 |
0.04 |
SVF |
remodeling |
||
P4HA2 |
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II | 1.47 |
0.00 |
— |
— |
5.42 |
0.00 |
— |
remodeling |
||
CHSY1 |
carbohydrate (chondroitin) synthase 1 | 1.44 |
3.65 |
— |
— |
— |
— |
— |
remodeling |
||
OMA1 |
OMA1 homolog, zinc metallopeptidase (S. cerevisiae) | 1.42 |
0.28 |
0.92 |
3.61 |
0.27 |
0.00 |
— |
remodeling |
||
ADAM9 |
ADAM metallopeptidase domain 9 (meltrin gamma) | 1.41 |
1.00 |
— |
— |
1.42 |
0.50 |
SVF |
remodeling |
||
GALNACT |
chondroitin sulfate GalNAcT-2 | 1.40 |
1.29 |
0.77 |
1.93 |
— |
— |
SVF |
remodeling |
||
ADAM17 |
ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) | 0.79 |
2.44 |
— |
— |
1.48 |
3.94 |
SVF |
remodeling |
||
ST3GAL6 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.77 |
3.65 |
— |
— |
— |
— |
— |
remodeling |
||
ST6GALN |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 | 0.76 |
3.07 |
— |
— |
— |
— |
— |
remodeling |
||
PLOD1 |
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 | 0.76 |
3.07 |
2.48 |
3.61 |
3.49 |
0.00 |
Adipocyte |
remodeling |
||
ADAM15 |
ADAM metallopeptidase domain 15 (metargidin) | 0.71 |
0.82 |
1.40 |
0.29 |
2.34 |
0.02 |
SVF |
remodeling |
||
CPM |
carboxypeptidase M | 0.63 |
1.00 |
— |
— |
2.63 |
0.00 |
Adipocyte |
remodeling |
||
CTSG |
cathepsin G | — |
— |
2.75 |
0.29 |
— |
— |
SVF |
remodeling |
||
GUSB |
glucuronidase, beta | — |
— |
2.73 |
2.23 |
0.70 |
1.63 |
SVF |
remodeling |
||
FUCA1 |
fucosidase, alpha-L- 1, tissue | — |
— |
2.62 |
1.20 |
0.60 |
0.00 |
SVF |
remodeling |
||
TIMP1 |
TIMP metallopeptidase inhibitor 1 | — |
— |
2.45 |
1.69 |
8.10 |
0.00 |
SVF |
remodeling |
||
IDUA |
iduronidase, alpha-L- | — |
— |
2.30 |
1.46 |
— |
— |
— |
remodeling |
||
HS3ST2 |
heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | — |
— |
2.24 |
2.96 |
— |
— |
SVF |
remodeling |
||
P4HB |
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | — |
— |
2.17 |
1.69 |
1.28 |
3.94 |
— |
remodeling |
||
CTSD |
cathepsin D (lysosomal aspartyl peptidase) | — |
— |
2.15 |
1.69 |
1.20 |
3.94 |
Adipocyte |
remodeling |
||
DPP8 |
dipeptidyl-peptidase 8 | — |
— |
2.14 |
1.46 |
1.25 |
3.94 |
— |
remodeling |
||
PLOD3 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | — |
— |
2.12 |
2.59 |
1.12 |
3.94 |
SVF |
remodeling |
||
MMP2 |
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | — |
— |
2.11 |
0.00 |
3.49 |
0.00 |
SVF |
remodeling |
||
CD37 |
CD37 molecule | — |
— |
2.04 |
2.59 |
1.23 |
3.94 |
SVF |
remodeling |
||
ST3GAL5 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | — |
— |
2.02 |
1.93 |
1.24 |
3.94 |
SVF |
remodeling |
||
NAGPA |
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | — |
— |
1.94 |
4.32 |
— |
— |
— |
remodeling |
||
CD209 |
CD209 molecule | — |
— |
1.91 |
0.19 |
— |
— |
SVF |
remodeling |
||
GBGT1 |
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 | — |
— |
1.89 |
2.59 |
— |
— |
— |
remodeling |
||
IDS |
iduronate 2-sulfatase (Hunter syndrome) | — |
— |
1.79 |
0.66 |
— |
— |
Adipocyte |
remodeling |
||
STT3B |
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) | — |
— |
1.78 |
1.46 |
1.31 |
3.94 |
— |
remodeling |
||
FLJ21865 |
endo-beta-N-acetylglucosaminidase | — |
— |
1.76 |
1.20 |
— |
— |
SVF |
remodeling |
||
TPSG1 |
tryptase gamma 1 | — |
— |
1.74 |
0.73 |
— |
— |
SVF |
remodeling |
||
MGAT5 |
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | — |
— |
1.73 |
2.96 |
0.24 |
0.00 |
— |
remodeling |
||
CTSF |
cathepsin F | — |
— |
1.72 |
4.32 |
1.45 |
3.24 |
Adipocyte |
remodeling |
||
BMP1 |
bone morphogenetic protein 1 | — |
— |
1.72 |
1.93 |
3.21 |
0.00 |
— |
remodeling |
||
HPSE2 |
heparanase 2 | — |
— |
1.72 |
3.61 |
— |
— |
Adipocyte |
remodeling |
||
PCOLCE |
procollagen C-endopeptidase enhancer | — |
— |
1.70 |
2.96 |
4.89 |
0.00 |
SVF |
remodeling |
||
TIMP2 |
TIMP metallopeptidase inhibitor 2 | — |
— |
1.68 |
0.66 |
1.45 |
0.92 |
SVF |
remodeling |
||
GYLTL1B |
glycosyltransferase-like 1B | — |
— |
1.67 |
0.00 |
— |
— |
— |
remodeling |
||
HEXA |
hexosaminidase A (alpha polypeptide) | — |
— |
1.62 |
0.85 |
3.14 |
0.00 |
SVF |
remodeling |
||
B4GALT4 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | — |
— |
1.62 |
1.46 |
0.66 |
0.50 |
— |
remodeling |
||
GAL3ST1 |
galactose-3-O-sulfotransferase 1 | — |
— |
1.56 |
2.59 |
1.26 |
3.94 |
SVF |
remodeling |
||
HS3ST5 |
heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | — |
— |
1.49 |
2.23 |
— |
— |
SVF |
remodeling |
||
ST8SIA5 |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | — |
— |
1.48 |
0.33 |
2.29 |
0.00 |
— |
remodeling |
||
B3GALT6 |
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 | — |
— |
1.46 |
0.33 |
1.20 |
3.94 |
SVF |
remodeling |
||
MAN1B1 |
mannosidase, alpha, class 1B, member 1 | — |
— |
1.45 |
0.33 |
— |
— |
— |
remodeling |
||
NANS |
N-acetylneuraminic acid synthase (sialic acid synthase) | — |
— |
1.40 |
4.32 |
2.01 |
0.01 |
SVF |
remodeling |
||
ST6GAL1 |
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | — |
— |
1.33 |
1.46 |
1.55 |
0.37 |
SVF |
remodeling |
||
XPNPEP2 |
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | — |
— |
1.31 |
2.96 |
— |
— |
SVF |
remodeling |
||
HABP2 |
hyaluronan binding protein 2 | — |
— |
1.28 |
4.32 |
— |
— |
Adipocyte |
remodeling |
||
SLC35A2 |
solute carrier family 35 (UDP-galactose transporter), member A2 | — |
— |
1.27 |
2.96 |
— |
— |
— |
remodeling |
||
PIGQ |
phosphatidylinositol glycan anchor biosynthesis, class Q | — |
— |
1.26 |
1.69 |
— |
— |
SVF |
remodeling |
||
HS3ST4 |
heparan sulfate (glucosamine) 3-O-sulfotransferase 4 | — |
— |
1.26 |
3.61 |
0.48 |
0.00 |
Adipocyte |
remodeling |
||
ADAM11 |
ADAM metallopeptidase domain 11 | — |
— |
1.26 |
2.96 |
— |
— |
Adipocyte |
cell matrix adhesion |
||
MAN2B2 |
mannosidase, alpha, class 2B, member 2 | — |
— |
1.25 |
0.29 |
1.85 |
0.11 |
— |
remodeling |
||
POMT1 |
protein-O-mannosyltransferase 1 | — |
— |
1.22 |
0.29 |
2.00 |
0.00 |
— |
remodeling |
||
B3GALT4 |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 | — |
— |
1.20 |
0.33 |
1.56 |
0.18 |
— |
remodeling |
||
DPP9 |
dipeptidyl-peptidase 9 | — |
— |
1.18 |
2.96 |
3.27 |
0.50 |
— |
remodeling |
||
NPEPL1 |
aminopeptidase-like 1 | — |
— |
1.16 |
0.66 |
0.67 |
0.11 |
Adipocyte |
remodeling |
||
CHST10 |
carbohydrate sulfotransferase 10 | — |
— |
1.16 |
4.32 |
— |
— |
— |
cell matrix adhesion |
||
CHST12 |
carbohydrate (chondroitin 4) sulfotransferase 12 | — |
— |
1.16 |
2.59 |
1.73 |
0.00 |
SVF |
remodeling |
||
PIGB |
phosphatidylinositol glycan anchor biosynthesis, class B | — |
— |
1.15 |
1.20 |
0.74 |
3.89 |
Adipocyte |
remodeling |
||
ChGn |
chondroitin beta1,4 N-acetylgalactosaminyltransferase | — |
— |
1.14 |
0.73 |
2.24 |
0.00 |
— |
remodeling |
||
ARSB |
arylsulfatase B | — |
— |
1.12 |
1.46 |
1.09 |
3.94 |
— |
remodeling |
||
MGAT4B |
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | — |
— |
1.10 |
1.06 |
— |
— |
Adipocyte |
remodeling |
||
CPD |
carboxypeptidase D | — |
— |
0.91 |
2.59 |
— |
— |
SVF |
remodeling |
||
ADAM22 |
ADAM metallopeptidase domain 22 | — |
— |
0.89 |
1.93 |
1.30 |
3.24 |
SVF |
cell matrix adhesion |
||
ADAM7 |
ADAM metallopeptidase domain 7 | — |
— |
0.87 |
2.59 |
— |
— |
— |
remodeling |
||
PLAU |
plasminogen activator, urokinase | — |
— |
0.86 |
4.32 |
1.90 |
1.25 |
SVF |
remodeling |
||
SLC35A3 |
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | — |
— |
0.86 |
2.59 |
— |
— |
— |
remodeling |
||
ST3GAL4 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | — |
— |
0.85 |
2.59 |
2.48 |
0.01 |
— |
remodeling |
||
PPP2R1A |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | — |
— |
0.85 |
2.59 |
1.05 |
3.94 |
— |
cell matrix adhesion |
||
ADAMTS1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 13 | — |
— |
0.85 |
3.61 |
— |
— |
— |
remodeling |
||
B4GALT3 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | — |
— |
0.83 |
1.06 |
— |
— |
SVF |
remodeling |
||
TMPRSS2 |
transmembrane protease, serine 2 | — |
— |
0.83 |
2.59 |
1.40 |
0.50 |
— |
remodeling |
||
MMP14 |
matrix metallopeptidase 14 (membrane-inserted) | — |
— |
0.81 |
0.73 |
— |
— |
SVF |
remodeling |
||
SLC35D1 |
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 | — |
— |
0.81 |
3.61 |
2.65 |
0.00 |
— |
remodeling |
||
FUT10 |
fucosyltransferase 10 (alpha (1,3) fucosyltransferase) | — |
— |
0.79 |
0.56 |
— |
— |
— |
remodeling |
||
PI3 |
peptidase inhibitor 3, skin-derived (SKALP) | — |
— |
0.79 |
0.85 |
— |
— |
SVF |
remodeling |
||
ST6GALN |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3) -N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | — |
— |
0.78 |
2.23 |
0.12 |
0.00 |
SVF |
remodeling |
||
SULF1 |
sulfatase 1 | — |
— |
0.76 |
3.61 |
1.85 |
0.92 |
SVF |
remodeling |
||
EXTL2 |
exostoses (multiple)-like 2 | — |
— |
0.76 |
1.46 |
1.30 |
0.26 |
SVF |
remodeling |
||
LARGE |
like-glycosyltransferase | — |
— |
0.75 |
1.06 |
1.29 |
2.11 |
SVF |
remodeling |
||
MGAT2 |
mannosyl (alpha-1,6-) -glycoprotein beta-1,2-N-acetylglucosaminyltransferase | — |
— |
0.74 |
1.06 |
1.95 |
0.01 |
SVF |
remodeling |
||
ALG6 |
asparagine-linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase) | — |
— |
0.73 |
2.23 |
— |
— |
— |
remodeling |
||
HS6ST2 |
heparan sulfate 6-O-sulfotransferase 2 | — |
— |
0.73 |
1.20 |
— |
— |
— |
remodeling |
||
MMP7 |
matrix metallopeptidase 7 (matrilysin, uterine) | — |
— |
0.73 |
0.25 |
1.67 |
0.50 |
SVF |
remodeling |
||
ACHE |
acetylcholinesterase (Yt blood group) | — |
— |
0.72 |
1.46 |
0.52 |
0.00 |
— |
cell cell adhesion |
||
ADAM19 |
ADAM metallopeptidase domain 19 (meltrin beta) | — |
— |
0.72 |
0.00 |
0.84 |
4.77 |
SVF |
remodeling |
||
MGAT3 |
mannosyl (beta-1,4-) -glycoprotein beta-1,4-N-acetylglucosaminyltransferase | — |
— |
0.71 |
0.00 |
1.09 |
3.94 |
SVF |
remodeling |
||
MMP11 |
matrix metallopeptidase 11 (stromelysin 3) | — |
— |
0.69 |
0.33 |
— |
— |
SVF |
remodeling |
||
B4GALNT |
beta-1,4-N-acetyl-galactosaminyl transferase 1 | — |
— |
0.68 |
0.48 |
— |
— |
SVF |
remodeling |
||
EXT2 |
exostoses (multiple) 2 | — |
— |
0.67 |
0.56 |
0.72 |
2.11 |
— |
remodeling |
||
MMP13 |
matrix metallopeptidase 13 (collagenase 3) | — |
— |
0.66 |
4.32 |
— |
— |
— |
remodeling |
||
B3GALT2 |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 | — |
— |
0.62 |
0.45 |
— |
— |
— |
remodeling |
||
ECEL1 |
endothelin converting enzyme-like 1 | — |
— |
0.54 |
0.73 |
— |
— |
— |
remodeling |
||
PLAUR |
plasminogen activator, urokinase receptor | — |
— |
0.53 |
0.33 |
1.07 |
3.94 |
SVF |
remodeling |
||
ADAMTS1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 | — |
— |
0.43 |
0.25 |
0.74 |
2.63 |
SVF |
remodeling |
||
MMP15 |
matrix metallopeptidase 15 (membrane-inserted) | — |
— |
0.35 |
0.33 |
— |
— |
— |
remodeling |
||
MMP3 |
matrix metallopeptidase 3 (stromelysin 1, progelatinase) | — |
— |
— |
— |
37.99 |
0.00 |
— |
remodeling |
||
MMP1 |
matrix metallopeptidase 1 (interstitial collagenase) | — |
— |
— |
— |
22.76 |
0.00 |
Adipocyte |
remodeling |
||
MMP9 |
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | — |
— |
— |
— |
7.06 |
0.00 |
SVF |
remodeling |
||
LOXL1 |
lysyl oxidase-like 1 | — |
— |
— |
— |
2.34 |
0.01 |
SVF |
remodeling |
||
Other components |
|||||||||||
DCBLD2 |
discoidin, CUB and LCCL domain containing 2 | 1.87 |
1.00 |
0.84 |
2.23 |
1.50 |
0.11 |
— |
cell matrix adhesion |
||
ESM1 |
endothelial cell-specific molecule 1 | 1.38 |
0.28 |
— |
— |
2.50 |
0.01 |
— |
proper matrix |
||
MAGI1 |
membrane associated guanylate kinase, WW and PDZ domain containing 1 | 0.76 |
1.67 |
— |
— |
0.55 |
0.00 |
Adipocyte |
cell matrix adhesion |
||
SYMPK |
symplekin | 0.76 |
3.07 |
— |
— |
0.40 |
0.00 |
Adipocyte |
cell cell adhesion |
||
GJA12 |
gap junction protein, alpha 12, 47kDa | 0.75 |
1.00 |
— |
— |
0.44 |
0.00 |
SVF |
cell cell adhesion |
||
GJA4 |
gap junction protein, alpha 4, 37kDa (connexin 37) | 0.74 |
1.00 |
— |
— |
— |
— |
SVF |
cell cell adhesion |
||
PRELP |
proline/arginine-rich end leucine-rich repeat protein | 0.73 |
3.07 |
— |
— |
— |
— |
Adipocyte |
cell matrix adhesion |
||
F3 |
coagulation factor III (thromboplastin, tissue factor) | 0.72 |
1.54 |
0.63 |
1.06 |
3.51 |
0.00 |
— |
remodeling |
||
CEECAM1 |
cerebral endothelial cell adhesion molecule 1 | — |
— |
2.67 |
2.96 |
— |
— |
Adipocyte |
cell cell adhesion |
||
CD34 |
CD34 molecule | — |
— |
2.20 |
1.69 |
— |
— |
SVF |
cell matrix adhesion |
||
F13A1 |
coagulation factor XIII, A1 polypeptide | — |
— |
2.03 |
3.61 |
1.55 |
0.08 |
SVF |
remodeling |
||
WISP2 |
WNT1 inducible signaling pathway protein 2 | — |
— |
1.94 |
1.93 |
1.33 |
3.94 |
SVF |
cell matrix adhesion |
||
EFEMP2 |
EGF-containing fibulin-like extracellular matrix protein 2 | — |
— |
1.83 |
1.46 |
3.07 |
0.00 |
Adipocyte |
proper matrix |
||
ECM1 |
extracellular matrix protein 1 | — |
— |
1.68 |
3.61 |
2.06 |
0.70 |
SVF |
proper matrix |
||
CGN |
cingulin | — |
— |
1.63 |
4.32 |
— |
— |
— |
cell cell adhesion |
||
DCHS1 |
dachsous 1 (Drosophila) | — |
— |
1.57 |
0.56 |
— |
— |
SVF |
cell matrix adhesion |
||
TMEM16G |
transmembrane protein 16G | — |
— |
1.54 |
1.20 |
— |
— |
Adipocyte |
cell matrix adhesion |
||
TYRO3 |
TYRO3 protein tyrosine kinase | — |
— |
1.53 |
2.96 |
— |
— |
Adipocyte |
cell matrix adhesion |
||
FSTL1 |
follistatin-like 1 | — |
— |
1.32 |
3.61 |
1.21 |
3.94 |
SVF |
cell matrix adhesion |
||
PGM5 |
phosphoglucomutase 5 | — |
— |
1.30 |
2.23 |
— |
— |
SVF |
cell cell adhesion |
||
DCBLD1 |
discoidin, CUB and LCCL domain containing 1 | — |
— |
1.30 |
2.96 |
— |
— |
— |
cell matrix adhesion |
||
CNTN2 |
contactin 2 (axonal) | — |
— |
1.24 |
0.45 |
2.10 |
0.00 |
— |
cell matrix adhesion |
||
BSG |
basigin (Ok blood group) | — |
— |
1.24 |
0.00 |
1.95 |
0.18 |
Adipocyte |
cell matrix adhesion |
||
CNTN5 |
contactin 5 | — |
— |
1.24 |
0.85 |
— |
— |
— |
cell matrix adhesion |
||
F11R |
F11 receptor | — |
— |
1.22 |
2.59 |
— |
— |
— |
cell cell adhesion |
||
CEACAM1 |
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | — |
— |
1.21 |
0.00 |
2.10 |
0.00 |
— |
cell matrix adhesion |
||
SPG7 |
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) | — |
— |
1.17 |
0.73 |
2.45 |
0.01 |
— |
cell matrix adhesion |
||
VASN |
vasorin | — |
— |
1.16 |
2.59 |
— |
— |
SVF |
cell matrix adhesion |
||
LRRC4B |
leucine rich repeat containing 4B | — |
— |
1.16 |
4.32 |
— |
— |
Adipocyte |
cell matrix adhesion |
||
ADRM1 |
adhesion regulating molecule 1 | — |
— |
1.15 |
4.32 |
2.38 |
0.00 |
— |
cell matrix adhesion |
||
PARD6G |
par-6 partitioning defective 6 homolog gamma (C. elegans) | — |
— |
1.11 |
2.96 |
— |
— |
— |
cell cell adhesion |
||
VEZT |
vezatin, adherens junctions transmembrane protein | — |
— |
0.89 |
0.56 |
0.72 |
1.25 |
— |
cell cell adhesion |
||
JAM2 |
junctional adhesion molecule 2 | — |
— |
0.86 |
3.61 |
— |
— |
SVF |
cell cell adhesion |
||
CEACAM4 |
carcinoembryonic antigen-related cell adhesion molecule 4 | — |
— |
0.85 |
3.61 |
— |
— |
SVF |
cell cell adhesion |
||
FAT2 |
FAT tumor suppressor homolog 2 (Drosophila) | — |
— |
0.84 |
2.23 |
— |
— |
— |
cell matrix adhesion |
||
CLDN7 |
claudin 7 | — |
— |
0.81 |
3.61 |
— |
— |
SVF |
cell cell adhesion |
||
GJC1 |
gap junction protein, chi 1, 31.9kDa (connexin 31.9) | — |
— |
0.80 |
2.23 |
— |
— |
SVF |
cell cell adhesion |
||
MPZL1 |
myelin protein zero-like 1 | — |
— |
0.80 |
0.66 |
1.50 |
1.25 |
SVF |
cell matrix adhesion |
||
ICAM3 |
intercellular adhesion molecule 3 | — |
— |
0.80 |
1.69 |
0.86 |
4.06 |
— |
cell cell adhesion |
||
CLDN12 |
claudin 12 | — |
— |
0.79 |
2.96 |
— |
— |
— |
cell cell adhesion |
||
PKHD1 |
polycystic kidney and hepatic disease 1 (autosomal recessive) | — |
— |
0.79 |
1.69 |
— |
— |
— |
cell cell adhesion |
||
CLDN8 |
claudin 8 | — |
— |
0.78 |
1.46 |
— |
— |
— |
cell cell adhesion |
||
RELN |
reelin | — |
— |
0.78 |
0.33 |
1.76 |
0.00 |
— |
cell matrix adhesion |
||
MATN3 |
matrilin 3 | — |
— |
0.78 |
2.59 |
— |
— |
SVF |
proper matrix |
||
ASTN1 |
astrotactin 1 | — |
— |
0.74 |
4.32 |
— |
— |
SVF |
cell cell adhesion |
||
ROBO1 |
roundabout, axon guidance receptor, homolog 1 (Drosophila) | — |
— |
0.73 |
0.45 |
1.83 |
0.50 |
— |
cell matrix adhesion |
||
GJA1 |
gap junction protein, alpha 1, 43kDa (connexin 43) | — |
— |
0.71 |
0.33 |
1.32 |
3.89 |
SVF |
cell cell adhesion |
||
PANX1 |
pannexin 1 | — |
— |
0.70 |
0.45 |
2.06 |
0.06 |
SVF |
cell cell adhesion |
||
ICAM1 |
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | — |
— |
0.66 |
0.56 |
1.86 |
0.02 |
SVF |
cell cell adhesion |
||
MADCAM1 |
mucosal vascular addressin cell adhesion molecule 1 | — |
— |
0.61 |
0.25 |
— |
— |
SVF |
cell matrix adhesion |
||
AMIGO2 |
adhesion molecule with Ig-like domain 2 | — |
— |
0.59 |
3.61 |
— |
— |
SVF |
cell cell adhesion |
||
VNN2 |
vanin 2 | — |
— |
0.54 |
0.73 |
— |
— |
SVF |
cell matrix adhesion |
||
ICAM5 |
intercellular adhesion molecule 5, telencephalin | — |
— |
0.47 |
0.00 |
— |
— |
Adipocyte |
cell cell adhesion |
||
CEACAM6 |
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | — |
— |
0.43 |
0.00 |
— |
— |
SVF |
cell cell adhesion |
||
CYR61 |
cysteine-rich, angiogenic inducer, 61 | — |
— |
0.23 |
0.00 |
3.42 |
0.00 |
Adipocyte |
cell cell adhesion |
||
CRISPLD2 |
cysteine-rich secretory protein LCCL domain containing 2 | — |
— |
— |
— |
4.01 |
0.00 |
SVF |
cell cell adhesion |
||
TNC |
tenascin C (hexabrachion) | — |
— |
— |
— |
3.57 |
0.00 |
SVF |
cell matrix adhesion |
||
CD99 |
CD99 molecule | — |
— |
— |
— |
2.24 |
0.00 |
SVF |
cell matrix adhesion |
||
SVF = Stroma Vascular Fraction
The indicated fold variations were measured in the cDNA microarray experiments. Differential expression q-values (expressed as percentages of false positive results) were computed with the SAM algorithm.