..........................................................................................................................
Rank ID Term
List
Hits
List
Total
Population
Hits
Population
Total
P-value Genes ID's Genes Names
1
GO:0030528
transcription regulator activity
124 1181 216 2421 4.82e-03 mediator of RNA polymerase II transcription, subunit 6 homolog (S. cerevisiae) tripartite motif-containing 28 tripartite motif-containing 22 caudal type homeobox transcription factor 1 Kruppel-like factor 1 (erythroid) AT rich interactive domain 5A (MRF1-like) transcription elongation regulator 1 trinucleotide repeat containing 4 zinc fingers and homeoboxes 1 POU domain, class 6, transcription factor 2 zinc finger protein 452 GLIS family zinc finger 1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 AT rich interactive domain 3A (BRIGHT- like) early growth response 1 E74-like factor 1 (ets domain transcription factor) ELK4, ETS-domain protein (SRF accessory protein 1) engrailed homolog 2 estrogen receptor 2 (ER beta) estrogen-related receptor alpha ets variant gene 4 (E1A enhancer binding protein, E1AF) forkhead box F2 forkhead box D1 forkhead box I1 forkhead box M1 forkhead box O3A v-fos FBJ murine osteosarcoma viral oncogene homolog zinc finger protein 95 homolog (mouse) v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) zinc finger and BTB domain containing 38 general transcription factor IIE, polypeptide 2, beta 34kDa host cell factor C2 host cell factor C1 (VP16-accessory protein) Kv channel interacting protein 3, calsenilin hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) forkhead box A1 homeobox A1 homeobox A9 homeobox A13 homeobox B3 interferon regulatory factor 8 forkhead box K2 interferon regulatory factor 5 interferon regulatory factor 6 ISL1 transcription factor, LIM/homeodomain, (islet-1) jun oncogene jun B proto-oncogene zinc finger protein 307 MAX dimerization protein 1 nuclear receptor subfamily 3, group C, member 2 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 myogenic factor 6 (herculin) myogenic differentiation 1 myogenin (myogenic factor 4) activating transcription factor 1 activating transcription factor 3 nuclear factor (erythroid-derived 2), 45kDa nuclear factor (erythroid-derived 2)-like 2 nuclear factor, interleukin 3 regulated nuclear factor I/X (CCAAT-binding transcription factor) nuclear transcription factor Y, alpha nuclear transcription factor Y, beta paired box gene 6 (aniridia, keratitis) polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa hairy and enhancer of split 2 (Drosophila) PPAR binding protein RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) BCL6 co-repressor hairy and enhancer of split 6 (Drosophila) hairless homolog (mouse) NF-kappaB repressing factor tubby like protein 4 PHD finger protein 12 zinc finger protein 71 retinoic acid receptor, beta v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) regulatory factor X, 2 (influences HLA class II expression) regulatory factor X, 3 (influences HLA class II expression) BTB and CNC homology 1, basic leucine zipper transcription factor 2 sal-like 2 (Drosophila) sal-like 1 (Drosophila) PR domain containing 16 sine oculis homeobox homolog 1 (Drosophila) SRY (sex determining region Y)-box 15 Sp3 transcription factor Spi-B transcription factor (Spi-1/PU.1 related) signal transducer and activator of transcription 4 signal transducer and activator of transcription 6, interleukin-4 induced Kruppel-like factor 9 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa TATA box binding protein transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) transcription factor 7 (T-cell specific, HMG-box) transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) vacuolar protein sorting 72 (S. cerevisiae) TEA domain family member 4 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) transcription factor AP-4 (activating enhancer binding protein 4) tumor protein p73 vitamin D (1,25- dihydroxyvitamin D3) receptor Wilms tumor 1 zinc finger protein, X-linked zinc finger protein 131 zinc finger protein 140 zinc finger protein 217 BTG family, member 2 nuclear receptor subfamily 4, group A, member 3 FOS-like antigen 1 nuclear receptor interacting protein 1 runt-related transcription factor 2 Cas-Br-M (murine) ecotropic retroviral transforming sequence cellular repressor of E1A-stimulated genes 1 Sin3A-associated protein, 30kDa tripartite motif-containing 15 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae) metastasis associated 1 Kruppel-like factor 4 (gut) general transcription factor IIIC, polypeptide 4, 90kDa cAMP responsive element binding protein 5 nuclear factor (erythroid-derived 2)-like 3 TSC22 domain family, member 2 thyroid hormone receptor associated protein 1
2
GO:0004872
receptor activity
109 1181 178 2421 3.57e-04 mediator of RNA polymerase II transcription, subunit 6 homolog (S. cerevisiae) glycoprotein A33 (transmembrane) opioid receptor, sigma 1 gonadotropin-releasing hormone (type 2) receptor 2 anthrax toxin receptor 2 chemokine (C-C motif) receptor 7 leukotriene B4 receptor interleukin-1 receptor-associated kinase 1 binding protein 1 nuclear receptor coactivator 7 colony stimulating factor 3 receptor (granulocyte) adrenergic, alpha-2B-, receptor B and T lymphocyte associated chemokine (C-X3-C motif) receptor 1 progestin and adipoQ receptor family member III hypothetical protein FLJ31951 G protein-coupled receptor 156 angiotensin II receptor, type 1 Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 endothelial differentiation, sphingolipid G-protein-coupled receptor, 3 endothelin receptor type B cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) EPH receptor A2 EPH receptor A1 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) coagulation factor II (thrombin) receptor coagulation factor II (thrombin) receptor-like 1 olfactory receptor, family 9, subfamily Q, member 1 G protein-coupled receptor 115 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) CD93 molecule formyl peptide receptor 1 protein kinase D3 interleukin 17 receptor A MAM domain containing 2 natural cytotoxicity triggering receptor 3 G protein-coupled receptor 137C G protein-coupled receptor 17 G protein-coupled receptor 35 glutamate receptor, ionotrophic, AMPA 3 glutamate receptor, metabotropic 2 low density lipoprotein-related protein 12 deoxynucleotidyltransferase, terminal, interacting protein 2 5-hydroxytryptamine (serotonin) receptor 2B 5-hydroxytryptamine (serotonin) receptor 6 G protein-coupled receptor 109A olfactory receptor, family 10, subfamily R, member 2 interferon gamma receptor 1 interleukin 2 receptor, alpha interleukin 10 receptor, beta integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, beta 4 integrin, beta 6 inositol 1,4,5-triphosphate receptor, type 3 leukocyte-associated immunoglobulin-like receptor 1 leukemia inhibitory factor receptor alpha low density lipoprotein receptor-related protein 4 tumor-associated calcium signal transducer 2 CD46 molecule, complement regulatory protein macrophage stimulating 1 receptor (c-met-related tyrosine kinase) natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) neuropeptide Y receptor Y1 receptor tyrosine kinase-like orphan receptor 2 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) opioid receptor, kappa 1 purinergic receptor P2Y, G-protein coupled, 1 tumor necrosis factor receptor superfamily, member 12A chemokine (C-C motif) receptor-like 1 polycystic kidney and hepatic disease 1 (autosomal recessive) plasminogen activator, urokinase receptor fibroblast growth factor receptor-like 1 triggering receptor expressed on myeloid cells 1 PPAR binding protein arginine vasopressin receptor 1A protein kinase C, alpha protein kinase C, beta 1 protein kinase C, epsilon protein kinase C, iota protein kinase D1 prolactin receptor plexin domain containing 1 patched homolog 1 (Drosophila) prostaglandin E receptor 2 (subtype EP2), 53kDa brain-specific angiogenesis inhibitor 2 protein tyrosine phosphatase, non-receptor type 2 retinal G protein coupled receptor tumor necrosis factor receptor superfamily, member 17 roundabout, axon guidance receptor, homolog 1 (Drosophila) limb region 1 homolog (mouse) reticulon 4 receptor solute carrier family 20 (phosphate transporter), member 2 somatostatin receptor 1 transforming growth factor, beta receptor II (70/80kDa) interleukin 1 receptor, type II frizzled homolog 5 (Drosophila) olfactory receptor, family 2, subfamily A, member 4 calcitonin receptor killer cell lectin-like receptor subfamily C, member 4 interleukin 18 receptor 1 G protein-coupled receptor, family C, group 5, member A activin A receptor, type IIA CD8b molecule pleckstrin homology, Sec7 and coiled-coil domains 3 G protein-coupled receptor 56 membrane-spanning 4-domains, subfamily A, member 1 activin A receptor type II-like 1 CD28 molecule CD80 molecule thyroid hormone receptor associated protein 1
3
GO:0001584
rhodopsin-like receptor activity
29 1181 40 2421 1.86e-03 gonadotropin-releasing hormone (type 2) receptor 2 chemokine (C-C motif) receptor 7 leukotriene B4 receptor adrenergic, alpha-2B-, receptor chemokine (C-X3-C motif) receptor 1 angiotensin II receptor, type 1 Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 endothelial differentiation, sphingolipid G-protein-coupled receptor, 3 endothelin receptor type B coagulation factor II (thrombin) receptor coagulation factor II (thrombin) receptor-like 1 olfactory receptor, family 9, subfamily Q, member 1 formyl peptide receptor 1 G protein-coupled receptor 17 G protein-coupled receptor 35 5-hydroxytryptamine (serotonin) receptor 2B 5-hydroxytryptamine (serotonin) receptor 6 G protein-coupled receptor 109A olfactory receptor, family 10, subfamily R, member 2 neuropeptide Y receptor Y1 opioid receptor, kappa 1 purinergic receptor P2Y, G-protein coupled, 1 chemokine (C-C motif) receptor-like 1 arginine vasopressin receptor 1A prostaglandin E receptor 2 (subtype EP2), 53kDa retinal G protein coupled receptor somatostatin receptor 1 olfactory receptor, family 2, subfamily A, member 4
4
GO:0005125
cytokine activity
29 1181 42 2421 5.96e-03 chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) colony stimulating factor 3 (granulocyte) CKLF-like MARVEL transmembrane domain containing 2 sprouty-related, EVH1 domain containing 1 endothelial cell growth factor 1 (platelet-derived) sprouty-related, EVH1 domain containing 2 cardiotrophin-like cytokine factor 1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) chemokine (C-X-C motif) ligand 3 interleukin 1, alpha interleukin 6 (interferon, beta 2) interleukin 11 amphiregulin (schwannoma-derived growth factor) leukemia inhibitory factor (cholinergic differentiation factor) tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) chemokine (C-C motif) ligand 28 chemokine (C-C motif) ligand 2 chemokine (C-C motif) ligand 11 chemokine (C-C motif) ligand 20 chemokine (C motif) ligand 1 chemokine (C-X3-C motif) ligand 1 transforming growth factor, beta 2 thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) secretoglobin, family 1A, member 1 (uteroglobin) vascular endothelial growth factor A secretogranin II (chromogranin C) tyrosyl-tRNA synthetase growth differentiation factor 15 brain and reproductive organ-expressed (TNFRSF1A modulator)
5
GO:0008083
growth factor activity
21 1181 29 2421 8.2e-03 chondroitin sulfate proteoglycan 5 (neuroglycan C) colony stimulating factor 3 (granulocyte) endothelial cell growth factor 1 (platelet-derived) epidermal growth factor (beta-urogastrone) epiregulin cardiotrophin-like cytokine factor 1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) interleukin 1, alpha interleukin 6 (interferon, beta 2) interleukin 11 amphiregulin (schwannoma-derived growth factor) leukemia inhibitory factor (cholinergic differentiation factor) Norrie disease (pseudoglioma) nerve growth factor, beta polypeptide transforming growth factor, beta 2 thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) vascular endothelial growth factor A vascular endothelial growth factor C 26 serine protease growth differentiation factor 15 neuregulin 2
6
GO:0008528
peptide receptor activity, G-protein coupled
11 1181 13 2421 8.77e-03 angiotensin II receptor, type 1 endothelin receptor type B coagulation factor II (thrombin) receptor coagulation factor II (thrombin) receptor-like 1 sortilin-related VPS10 domain containing receptor 3 formyl peptide receptor 1 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) neuropeptide Y receptor Y1 opioid receptor, kappa 1 arginine vasopressin receptor 1A somatostatin receptor 1
7
GO:0004896
hematopoietin/interferon-class (D200-domain) cytokine receptor activity
10 1181 12 2421 1.55e-02 colony stimulating factor 3 receptor (granulocyte) interleukin 17 receptor A interferon gamma receptor 1 interleukin 1 receptor, type I interleukin 2 receptor, alpha interleukin 10 receptor, beta leukemia inhibitory factor receptor alpha prolactin receptor interleukin 1 receptor, type II interleukin 18 receptor 1
8
GO:0015276
ligand-gated ion channel activity
8 1181 10 2421 4.63e-02 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) inositol 1,4,5-triphosphate receptor, type 3 cyclic nucleotide gated channel beta 3 sodium channel, nonvoltage-gated 1 alpha sodium channel, nonvoltage-gated 1, delta transient receptor potential cation channel, subfamily C, member 1 transient receptor potential cation channel, subfamily C, member 6 amiloride-sensitive cation channel 3
9
GO:0015370
solute:sodium symporter activity
5 1181 5 2421 2.75e-02 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 solute carrier family 5 (sodium-dependent vitamin transporter), member 6
10
GO:0043176
amine binding
5 1181 5 2421 2.75e-02 cholinergic receptor, nicotinic, alpha 3 cholinergic receptor, nicotinic, delta acetylcholinesterase (Yt blood group) ornithine carbamoyltransferase phenylalanine hydroxylase
..........................................................................................................................