..........................................................................................................................
Rank
ID
Term
List
Hits
List
Total
Population
Hits
Population
Total
P-value
Genes ID's
Genes Names
1
04010
MAPK signaling pathway
37
418
60
868
2.07e-02
growth arrest and DNA-damage-inducible, gamma dual specificity phosphatase 10 dual specificity phosphatase 1 dual specificity phosphatase 2 dual specificity phosphatase 5 epidermal growth factor (beta-urogastrone) ELK4, ETS-domain protein (SRF accessory protein 1) fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) v-fos FBJ murine osteosarcoma viral oncogene homolog interleukin 1, alpha interleukin 1 receptor, type I jun oncogene v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog mitogen-activated protein kinase kinase kinase 5 growth arrest and DNA-damage-inducible, beta nerve growth factor, beta polypeptide protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) protein kinase C, alpha protein kinase C, beta 1 mitogen-activated protein kinase 8 mitogen-activated protein kinase kinase 1 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) RAS p21 protein activator (GTPase activating protein) 1 mitogen-activated protein kinase kinase 4 v-raf murine sarcoma viral oncogene homolog B1 serine/threonine kinase 4 transforming growth factor, beta 2 transforming growth factor, beta receptor II (70/80kDa) calcium channel, voltage-dependent, beta 4 subunit interleukin 1 receptor, type II caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) caspase 4, apoptosis-related cysteine peptidase caspase 8, apoptosis-related cysteine peptidase mitogen-activated protein kinase kinase kinase 13 ribosomal protein S6 kinase, 90kDa, polypeptide 5 calcium channel, voltage-dependent, alpha 2/delta subunit 2 cell division cycle 42 (GTP binding protein, 25kDa)
2
04310
Wnt signaling pathway
18
418
27
868
3.87e-02
F-box and WD-40 domain protein 11 dickkopf homolog 2 (Xenopus laevis) glycogen synthase kinase 3 beta adenomatosis polyposis coli jun oncogene matrix metallopeptidase 7 (matrilysin, uterine) protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) protein kinase C, alpha protein kinase C, beta 1 mitogen-activated protein kinase 8 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) SUMO1/sentrin/SMT3 specific peptidase 2 transcription factor 7 (T-cell specific, HMG-box) wingless-type MMTV integration site family, member 5A frizzled homolog 5 (Drosophila) transducin (beta)-like 1X-linked receptor 1 FOS-like antigen 1
3
05210
Colorectal cancer
16
418
19
868
1.20e-03
v-fos FBJ murine osteosarcoma viral oncogene homolog glycogen synthase kinase 3 beta adenomatosis polyposis coli baculoviral IAP repeat-containing 5 (survivin) jun oncogene v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog phosphoinositide-3-kinase, catalytic, gamma polypeptide cytochrome c, somatic mitogen-activated protein kinase 8 mitogen-activated protein kinase kinase 1 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) v-raf murine sarcoma viral oncogene homolog B1 transcription factor 7 (T-cell specific, HMG-box) transforming growth factor, beta 2 transforming growth factor, beta receptor II (70/80kDa) frizzled homolog 5 (Drosophila)
4
04610
Complement and coagulation cascades
15
418
22
868
4.51e-02
carboxypeptidase B2 (plasma, carboxypeptidase U) coagulation factor II (thrombin) receptor coagulation factor III (thromboplastin, tissue factor) complement factor I CD46 molecule, complement regulatory protein serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 plasminogen activator, urokinase plasminogen activator, urokinase receptor mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) thrombomodulin complement component 1, r subcomponent complement component 4 binding protein, alpha complement component 6 complement component 8, alpha polypeptide complement component 8, beta polypeptide
5
04660
T cell receptor signaling pathway
15
418
19
868
5.74e-03
mucosa associated lymphoid tissue lymphoma translocation gene 1 v-fos FBJ murine osteosarcoma viral oncogene homolog jun oncogene v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha phosphoinositide-3-kinase, catalytic, gamma polypeptide protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) protein kinase C, theta vav 2 oncogene caspase recruitment domain family, member 11 Cas-Br-M (murine) ecotropic retroviral transforming sequence Cas-Br-M (murine) ecotropic retroviral transforming sequence b CD8b molecule CD28 molecule cell division cycle 42 (GTP binding protein, 25kDa)
6
04662
B cell receptor signaling pathway
15
418
18
868
2.16e-03
mucosa associated lymphoid tissue lymphoma translocation gene 1 v-fos FBJ murine osteosarcoma viral oncogene homolog glycogen synthase kinase 3 beta jun oncogene v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha phosphoinositide-3-kinase, catalytic, gamma polypeptide protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) protein kinase C, beta 1 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) spleen tyrosine kinase vav 2 oncogene caspase recruitment domain family, member 11 CD22 molecule CD79b molecule, immunoglobulin-associated beta
7
05220
Chronic myeloid leukemia
14
418
20
868
3.92e-02
cyclin-dependent kinase inhibitor 1A (p21, Cip1) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha phosphoinositide-3-kinase, catalytic, gamma polypeptide SHC (Src homology 2 domain containing) transforming protein 3 mitogen-activated protein kinase kinase 1 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) breakpoint cluster region v-raf murine sarcoma viral oncogene homolog B1 transforming growth factor, beta 2 transforming growth factor, beta receptor II (70/80kDa) Cas-Br-M (murine) ecotropic retroviral transforming sequence Cas-Br-M (murine) ecotropic retroviral transforming sequence b
8
05212
Pancreatic cancer
13
418
16
868
6.73e-03
epidermal growth factor (beta-urogastrone) v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog phosphoinositide-3-kinase, catalytic, gamma polypeptide mitogen-activated protein kinase 8 mitogen-activated protein kinase kinase 1 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) v-raf murine sarcoma viral oncogene homolog B1 transforming growth factor, beta 2 transforming growth factor, beta receptor II (70/80kDa) vascular endothelial growth factor A vascular endothelial growth factor C cell division cycle 42 (GTP binding protein, 25kDa)
9
00350
Tyrosine metabolism
10
418
12
868
1.35e-02
alcohol dehydrogenase 6 (class V) catechol-O-methyltransferase methyltransferase like 6 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) aldehyde oxidase 1 N-acetyltransferase 5 protein arginine methyltransferase 6 tyrosine hydroxylase tyrosinase (oculocutaneous albinism IA) tyrosinase-related protein 1
10
04150
mTOR signaling pathway
10
418
13
868
3.36e-02
rapamycin-insensitive companion of mTOR hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) insulin phosphoinositide-3-kinase, catalytic, gamma polypeptide protein kinase, AMP-activated, alpha 1 catalytic subunit ribosomal protein S6 kinase, 70kDa, polypeptide 1 v-raf murine sarcoma viral oncogene homolog B1 tuberous sclerosis 2 vascular endothelial growth factor A vascular endothelial growth factor C
11
04520
Adherens junction
9
418
10
868
7.61e-03
synovial sarcoma, X breakpoint 2 interacting protein protein tyrosine phosphatase, non-receptor type 1 protein tyrosine phosphatase, receptor type, B ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) snail homolog 1 (Drosophila) transcription factor 7 (T-cell specific, HMG-box) transforming growth factor, beta receptor II (70/80kDa) actinin, alpha 2 cell division cycle 42 (GTP binding protein, 25kDa)
12
04930
Type II diabetes mellitus
7
418
8
868
2.73e-02
insulin insulin receptor substrate 1 phosphoinositide-3-kinase, catalytic, gamma polypeptide protein kinase C, epsilon mitogen-activated protein kinase 8 solute carrier family 2 (facilitated glucose transporter), member 2 suppressor of cytokine signaling 3
..........................................................................................................................