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Rank ID Term
List
Hits
List
Total
Population
Hits
Population
Total
P-value Genes ID's Genes Names
1
GO:0005198
structural molecule activity
79 1240 127 2421 6.87e-03 actin related protein 2/3 complex, subunit 3, 21kDa actin related protein 2/3 complex, subunit 1B, 41kDa actin related protein 2/3 complex, subunit 2, 34kDa sorbin and SH3 domain containing 3 tubulin, beta 2C mitochondrial ribosomal protein L28 nestin actin-like 7B elastin microfibril interfacer 1 ribosomal protein L35 alpha-tubulin isotype H2-alpha adducin 1 (alpha) heat shock protein, alpha-crystallin-related, B6 collagen, type I, alpha 1 collagen, type I, alpha 2 collagen, type VI, alpha 1 collagen, type VI, alpha 2 collagen, type VI, alpha 3 ribosomal protein L10-like adaptor-related protein complex 2, alpha 2 subunit elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) tubulin, beta erythrocyte membrane protein band 4.1-like 1 erythrocyte membrane protein band 4.1-like 2 gamma tubulin ring complex protein (76p gene) ankyrin 1, erythrocytic mitochondrial ribosomal protein S18B mitochondrial ribosomal protein L18 EGF-containing fibulin-like extracellular matrix protein 2 laminin, alpha 5 laminin, beta 2 (laminin S) lens intrinsic membrane protein 2, 19kDa moesin ribosomal protein L10a nuclear mitotic apparatus protein 1 collagen, type V, alpha 3 villin-like mitochondrial ribosomal protein S7 mitochondrial ribosomal protein L27 phosphoglucomutase 5 periplakin mitochondrial ribosomal protein L16 mitochondrial ribosomal protein S18A actin, alpha 2, smooth muscle, aorta ribosomal protein L3-like ribosomal protein L5 ribosomal protein L6 ribosomal protein L10 ribosomal protein L11 ribosomal protein L12 ribosomal protein L15 ribosomal protein L18 ribosomal protein L27a ribosomal protein L28 ribosomal protein L32 mitochondrial ribosomal protein L12 ribosomal protein S3 ribosomal protein S4, X-linked ribosomal protein S10 ribosomal protein S12 ribosomal protein S16 ribosomal protein S23 ribosomal protein S24 ribosome binding protein 1 homolog 180kDa (dog) mitochondrial ribosomal protein S14 smoothelin spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) spectrin, beta, erythrocytic (includes spherocytosis, clinical type I) thrombospondin 2 thrombospondin 3 tenascin XB tropomyosin 2 (beta) titin collagen, type XIV, alpha 1 (undulin) vimentin mitochondrial ribosomal protein L24 talin 2 elastin microfibril interfacer 2 ribosomal protein L23
2
GO:0003723
RNA binding
67 1240 112 2421 3.82e-02 snurportin 1 leucine-rich PPR-motif containing RNA binding motif protein 6 nucleolar protein 5A (56kDa with KKE/D repeat) hexamethylene bis-acetamide inducible 1 KH domain containing, RNA binding, signal transduction associated 1 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) thioredoxin-like 4A DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 ribosomal protein L35 exosome component 8 cold inducible RNA binding protein alanyl-tRNA synthetase chromosome 14 open reading frame 21 eukaryotic translation initiation factor 4 gamma, 1 RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) solute carrier family 4 (anion exchanger), member 1, adaptor protein U2-associated SR140 protein PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) ribonuclease H1 RNA pseudouridylate synthase domain containing 2 polymerase I and transcript release factor heterogeneous nuclear ribonucleoprotein A1 lysyl-tRNA synthetase methionine-tRNA synthetase heterogeneous nuclear ribonucleoprotein M nuclear cap binding protein subunit 1, 80kDa neuro-oncological ventral antigen 1 poly(rC) binding protein 2 nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs) DiGeorge syndrome critical region gene 8 nuclear RNA export factor 3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 RNA binding motif protein 25 RNA binding motif (RNP1, RRM) protein 3 RNA binding motif, single stranded interacting protein 2 ribonuclease, RNase A family, 1 (pancreatic) apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G ribosomal protein L3-like ribosomal protein L5 ribosomal protein L6 ribosomal protein L11 ribosomal protein L12 ribosomal protein L18 ribosomal protein L27a ribosomal protein L28 mitochondrial ribosomal protein L12 ribophorin I ribosomal protein S3 ribosomal protein S4, X-linked ribosomal protein S10 ribosomal protein S12 RNA binding motif protein 26 superkiller viralicidic activity 2-like (S. cerevisiae) spleen focus forming virus (SFFV) proviral integration oncogene spi1 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 RD RNA binding protein poly(A) binding protein, nuclear 1 RNA binding motif protein 10 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa splicing factor, arginine/serine-rich 9 poly(A) binding protein, cytoplasmic 4 (inducible form) translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) KIAA0430 pumilio homolog 1 (Drosophila) SET domain containing 1A
3
GO:0016874
ligase activity
29 1240 44 2421 3.39e-02 STIP1 homology and U-box containing protein 1 ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) solute carrier family 27 (fatty acid transporter), member 4 solute carrier family 27 (fatty acid transporter), member 3 WW domain containing E3 ubiquitin protein ligase 2 ring finger protein 139 alanyl-tRNA synthetase MYC binding protein 2 tubulin tyrosine ligase-like family, member 12 mahogunin, ring finger 1 prolyl-tRNA synthetase (mitochondrial)(putative) glycyl-tRNA synthetase histidyl-tRNA synthetase lysyl-tRNA synthetase methionine-tRNA synthetase nuclear transcription factor, X-box binding 1 pyruvate carboxylase phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) ubiquitin-conjugating enzyme E2Q (putative) 1 glutaminyl-tRNA synthetase methylcrotonoyl-Coenzyme A carboxylase 2 (beta) ubiquitin-activating enzyme E1-like ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) valyl-tRNA synthetase HECT domain containing 3 threonyl-tRNA synthetase-like 1 acyl-CoA synthetase short-chain family member 1 tripartite motif-containing 5 ring finger protein 40
4
GO:0009055
electron carrier activity
27 1240 40 2421 2.67e-02 aldo-keto reductase family 1, member A1 (aldehyde reductase) protein disulfide isomerase family A, member 5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa cytochrome b-561 cytochrome c-1 electron-transfer-flavoprotein, beta polypeptide aldo-keto reductase family 1, member B1 (aldose reductase) 3-hydroxyanthranilate 3,4-dioxygenase thioredoxin 2 protein disulfide isomerase family A, member 3 isocitrate dehydrogenase 3 (NAD+) beta NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) NAD(P)H dehydrogenase, quinone 2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide phytanoyl-CoA 2-hydroxylase NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa tissue specific transplantation antigen P35B thioredoxin reductase 1 threonyl-tRNA synthetase-like 1 thioredoxin-like 5 protein disulfide isomerase family A, member 4
5
GO:0016779
nucleotidyltransferase activity
18 1240 23 2421 7.12e-03 polymerase (RNA) III (DNA directed) polypeptide C (62kD) polymerase (DNA directed) sigma polymerase (DNA directed), alpha 2 (70kD subunit) DNA directed RNA polymerase II polypeptide J-related gene polymerase (RNA) I polypeptide A, 194kDa GDP-mannose pyrophosphorylase B zinc ribbon domain containing 1 proliferating cell nuclear antigen phosphate cytidylyltransferase 1, choline, alpha polymerase (DNA directed), epsilon 3 (p17 subunit) N-acetylneuraminic acid synthase (sialic acid synthase) polymerase (DNA directed), delta 2, regulatory subunit 50kDa polymerase (DNA directed), epsilon polymerase (RNA) II (DNA directed) polypeptide H polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa polymerase (DNA-directed), epsilon 4 (p12 subunit) replication factor C (activator 1) 3, 38kDa 3'-phosphoadenosine 5'-phosphosulfate synthase 1
6
GO:0008324
cation transporter activity
16 1240 22 2421 3.34e-02 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d solute carrier family 12 (potassium/chloride transporters), member 7 ATPase, Class VI, type 11A solute carrier family 13 (sodium/sulfate symporters), member 4 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide ATPase, Na+/K+ transporting, beta 3 polypeptide ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E ATPase, H+ transporting, lysosomal accessory protein 1 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) solute carrier family 12 (potassium/chloride transporters), member 9 solute carrier family 12 (potassium/chloride transporters), member 4 ATPase, Class I, type 8B, member 4
7
GO:0016651
oxidoreductase activity, acting on NADH or NADPH
15 1240 19 2421 1.24e-02 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa cytochrome b-561 isocitrate dehydrogenase 3 (NAD+) beta isocitrate dehydrogenase 3 (NAD+) gamma NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) NAD(P)H dehydrogenase, quinone 2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa thioredoxin reductase 1 NADPH oxidase, EF-hand calcium binding domain 5
8
GO:0004553
hydrolase activity, hydrolyzing O-glycosyl compounds
14 1240 17 2421 8.18e-03 mannosidase, alpha, class 1B, member 1 glucosidase, alpha; neutral AB mannosidase, alpha, class 2B, member 2 fucosidase, alpha-L- 1, tissue glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) glucuronidase, beta hexosaminidase A (alpha polypeptide) iduronidase, alpha-L- oviductal glycoprotein 1, 120kDa (mucin 9, oviductin) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase SET domain containing 5 hypothetical protein FLJ10081 prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) similar to bK246H3.1 (immunoglobulin lambda-like polypeptide 1, pre-B-cell specific)
9
GO:0008238
exopeptidase activity
14 1240 18 2421 1.95e-02 N-acetylated alpha-linked acidic dipeptidase-like 1 dipeptidyl-peptidase 3 suppressor of Ty 16 homolog (S. cerevisiae) carboxypeptidase A3 (mast cell) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 AE binding protein 1 dipeptidyl-peptidase 7 dipeptidyl-peptidase 8 prolylcarboxypeptidase (angiotensinase C) X-prolyl aminopeptidase (aminopeptidase P) 1, soluble X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound aminopeptidase-like 1 dipeptidyl-peptidase 9 secernin 1
10
GO:0015399
primary active transporter activity
13 1240 17 2421 3.04e-02 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d ATPase, Class VI, type 11A Sec61 alpha 1 subunit (S. cerevisiae) DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide ATPase, Na+/K+ transporting, beta 3 polypeptide ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E ATPase, H+ transporting, lysosomal accessory protein 1 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) ATPase, Class I, type 8B, member 4
11
GO:0016875
ligase activity, forming carbon-oxygen bonds
12 1240 15 2421 2.17e-02 alanyl-tRNA synthetase prolyl-tRNA synthetase (mitochondrial)(putative) glycyl-tRNA synthetase histidyl-tRNA synthetase lysyl-tRNA synthetase methionine-tRNA synthetase Rho GTPase activating protein 17 nuclear receptor coactivator 5 glutaminyl-tRNA synthetase valyl-tRNA synthetase threonyl-tRNA synthetase-like 1 alanyl-tRNA synthetase domain containing 1
12
GO:0016782
transferase activity, transferring sulfur-containing groups
7 1240 7 2421 9.17e-03 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 F11 receptor carbohydrate (chondroitin 4) sulfotransferase 12 carbohydrate sulfotransferase 10 galactose-3-O-sulfotransferase 1 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
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