Genes DOWN -
KEGG Annotations
Used notations:
List Hits - the number of genes
annotated by the considered KEGG category or annotation cluster within
the analyzed list of target genes
List Total
- the number of genes within the analyzed list of target genes
having at least one KEGG annotation
Population Hits
- the number of genes, available on the entire microarray, annotated
by the considered KEGG category or annotation cluster
Population Total - the number of genes available on the
entire microarray and having at least one KEGG annotation
P-value - the significance p-value of
the gene enrichment of the considered KEGG category or annotation
cluster, calculated with a unilateral Fisher exact test
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Rank ID Term
List
Hits
List
Total
Population
Hits
Population
Total
P-value Genes ID's Genes Names
1
04910
Insulin signaling pathway
11 152 12 253 1.77e-02 ELK1, member of ETS oncogene family MAP kinase interacting serine/threonine kinase 2 acetyl-Coenzyme A carboxylase beta insulin receptor lipase, hormone-sensitive phosphorylase kinase, alpha 1 (muscle) phosphorylase kinase, alpha 2 (liver) protein kinase, AMP-activated, beta 2 non-catalytic subunit protein tyrosine phosphatase, receptor type, F v-raf-1 murine leukemia viral oncogene homolog 1 insulin receptor substrate 2
2
00071
Fatty acid metabolism
8 152 8 253 1.57e-02 alcohol dehydrogenase 1C (class I), gamma polypeptide carnitine palmitoyltransferase 1A (liver) carnitine palmitoyltransferase 1B (muscle) dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase) hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A dehydrogenase acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)
3
04920
Adipocytokine signaling pathway
7 152 7 253 2.67e-02 carnitine palmitoyltransferase 1A (liver) carnitine palmitoyltransferase 1B (muscle) acetyl-Coenzyme A carboxylase beta nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha protein kinase, AMP-activated, beta 2 non-catalytic subunit insulin receptor substrate 2 TNFRSF1A-associated via death domain
4
00310
Lysine degradation
6 152 6 253 4.52e-02 hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A dehydrogenase acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) retinol dehydrogenase 11 (all-trans/9-cis/11-cis) procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 serine hydroxymethyltransferase 1 (soluble)
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