Genes UP -
KEGG Annotations
Used notations:
List Hits - the number of genes
annotated by the considered KEGG category or annotation cluster within
the analyzed list of target genes
List Total
- the number of genes within the analyzed list of target genes
having at least one KEGG annotation
Population Hits
- the number of genes, available on the entire microarray, annotated
by the considered KEGG category or annotation cluster
Population Total - the number of genes available on the
entire microarray and having at least one KEGG annotation
P-value - the significance p-value of
the gene enrichment of the considered KEGG category or annotation
cluster, calculated with a unilateral Fisher exact test
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Rank ID Term
List
Hits
List
Total
Population
Hits
Population
Total
P-value Genes ID's Genes Names
1
04810
Regulation of actin cytoskeleton
9 101 11 253 4.95e-03 actin related protein 2/3 complex, subunit 5, 16kDa actin related protein 2/3 complex, subunit 1B, 41kDa IQ motif containing GTPase activating protein 2 fibroblast growth factor 1 (acidic) integrin, alpha M (complement component 3 receptor 3 subunit) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) integrin, beta 5
2
04514
Cell adhesion molecules (CAMs)
8 101 10 253 1.07e-02 major histocompatibility complex, class II, DQ alpha 1 HLA-G histocompatibility antigen, class I, G integrin, alpha M (complement component 3 receptor 3 subunit) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) protein tyrosine phosphatase, receptor type, C contactin associated protein 1
3
04512
ECM-receptor interaction
7 101 9 253 2.27e-02 collagen, type IV, alpha 1 collagen, type V, alpha 2 integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) integrin, beta 5 laminin, beta 1 secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)
4
04612
Antigen processing and presentation
7 101 8 253 7.56e-03 interferon, gamma-inducible protein 30 cathepsin B cathepsin S protein disulfide isomerase family A, member 3 major histocompatibility complex, class II, DQ alpha 1 HLA-G histocompatibility antigen, class I, G heat shock 70kDa protein 8
5
04650
Natural killer cell mediated cytotoxicity
6 101 8 253 4.66e-02 Fc fragment of IgG, low affinity IIIa, receptor (CD16a) FYN oncogene related to SRC, FGR, YES HLA-G histocompatibility antigen, class I, G integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) CD247 molecule
6
04640
Hematopoietic cell lineage
5 101 5 253 9.54e-03 Fc fragment of IgG, high affinity Ia, receptor (CD64) interleukin 1 receptor, type I integrin, alpha M (complement component 3 receptor 3 subunit) transferrin receptor (p90, CD71) CD9 molecule
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